12CL
Crystal structure of canine myeloperoxidase inhibited by SPIN from Staphylococcus delphini
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Myeloperoxidase | polymer | 741 | 83687.0 | 2 | UniProt (A0A8I3P7A7) Pfam (PF03098) | Canis lupus familiaris (dog) | |
| 2 | C, D (C, D) | SPIN family peroxidase inhibitor | polymer | 77 | 8611.5 | 2 | UniProt (A0A2A4GXB5) | Staphylococcus delphini | |
| 3 | E, H (F, I) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 4 | F, G (E, H) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1057.0 | 2 | In PDB GlyTouCan (G82348BZ) | |||
| 5 | EA, I (B, A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) PubChem (271) | |||
| 6 | FA, J (B, A) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 7 | GA, K (B, A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) PubChem (312) | |||
| 8 | HA, L, Y (B, A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) PubChem (24139) | |||
| 9 | IA, JA, M, N, P... (B, A) | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) PubChem (753) | |||
| 10 | KA, O, R, S (B, A) | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) PubChem (175) | |||
| 11 | AA, BA, CA, DA, LA... (B, A) | SULFATE ION | non-polymer | 96.1 | 10 | Chemie (SO4) | |||
| 12 | MA, NA, OA, PA (A, B, C, D) | water | water | 18.0 | 866 | Chemie (HOH) |
Sequence modifications
C, D: 28 - 99 (UniProt: A0A2A4GXB5)
| PDB | External Database | Details |
|---|---|---|
| Gly 23 | - | expression tag |
| Ser 24 | - | expression tag |
| Thr 25 | - | expression tag |
| Gly 26 | - | expression tag |
| Ser 27 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 184596.8 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 3287.0 | |
| Non-Polymers* | Number of molecules | 30 |
| Total formula weight | 3889.1 | |
| All* | Total formula weight | 191772.9 |
