12AZ
Human Ornithine Aminotransferase cocrystallized with its inhibitor, (3S,4R)-3-amino-4-cyanocyclopent-1-ene-1-carboxylic acid
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Ornithine aminotransferase, mitochondrial | polymer | 439 | 48593.7 | 3 | UniProt (P04181) Pfam (PF00202) | Homo sapiens (human) | Ornithine delta-aminotransferase,Ornithine--oxo-acid aminotransferase |
| 2 | D, J (A, C) | (3Z,4R)-4-cyano-3-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]cyclopent-1-ene-1-carboxylic acid | non-polymer | 381.3 | 2 | Chemie (A1DBG) | |||
| 3 | E (B) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 1 | Chemie (PLP) PubChem (1051) | |||
| 4 | F, G, H, I (B, C) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) PubChem (753) | |||
| 5 | K, L, M (A, B, C) | water | water | 18.0 | 873 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 145781.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1378.1 | |
| All* | Total formula weight | 147159.1 |
