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12AR

Cryo-EM structure of alpha-synuclein filaments (singlet) from M83(+/+) mouse brains with A53T mutation

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Alpha-synucleinpolymer14014506.11UniProt (P37840)Homo sapiens (human)Non-A beta component of AD amyloid,Non-A4 component of amyloid precursor,NACP
Sequence modifications
A: 1 - 140 (UniProt: P37840)
PDBExternal DatabaseDetails
Thr 53Ala 53engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight14506.1
All*Total formula weight14506.1
*Water molecules are not included.

260626

PDB entries from 2026-10-07

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