11YV
Structure of Bacillus subtilis Nitric Oxide Synthase in complex with 7-((3-(((3-(6-aminopyridin-2-yl)propyl)amino)methyl)phenoxy)methyl)quinolin-2-amine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Nitric oxide synthase oxygenase | polymer | 363 | 41787.1 | 1 | UniProt (O34453) Pfam (PF02898) | Bacillus subtilis subsp. subtilis str. 168 | NOSoxy-like protein |
| 2 | B (A) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 3 | C (A) | 7-{[3-({[4-(6-aminopyridin-2-yl)butyl]amino}methyl)phenoxy]methyl}quinolin-2-amine | non-polymer | 427.5 | 1 | Chemie (V5D) PubChem (155926526) | |||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 5 | E (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) PubChem (8117) | |||
| 6 | F, G, H, I (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) PubChem (753) | |||
| 7 | J, K (A) | N-PROPANOL | non-polymer | 60.1 | 2 | Chemie (POL) PubChem (1031) | |||
| 8 | L (A) | water | water | 18.0 | 414 | Chemie (HOH) |
Sequence modifications
A: 1 - 363 (UniProt: O34453)
| PDB | External Database | Details |
|---|---|---|
| Ala 25 | Glu 25 | engineered mutation |
| Ala 26 | Glu 26 | engineered mutation |
| Ala 316 | Glu 316 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41787.1 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1674.2 | |
| All* | Total formula weight | 43461.2 |
