11UF
GluA2-y5-CNIH1 open state + RR2b + Glu (LBD-TMD)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-5 subunit | polymer | 1049 | 117490.0 | 4 | UniProt (P19491) UniProt (Q8VHW4) | Rattus norvegicus (Norway rat) | GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,Neuronal voltage-gated calcium channel gamma-5 subunit,Transmembrane AMPAR regulatory protein gamma-5,TARP gamma-5 |
| 2 | E, F (E, F) | Protein cornichon homolog 1 | polymer | 144 | 16707.9 | 2 | UniProt (O95406) | Homo sapiens (human) | CNIH-1,Cornichon family AMPA receptor auxiliary protein 1,Protein cornichon homolog,T-cell growth-associated molecule 77,TGAM77 |
| 3 | G, H, J, K (A, B, C, D) | GLUTAMIC ACID | non-polymer | 147.1 | 4 | Chemie (GLU) PubChem (33032) | |||
| 4 | I, L (B, D) | N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dipropane-2-sulfonamide | non-polymer | 480.7 | 2 | Chemie (FWF) PubChem (44468130) |
Sequence modifications
A, B, C, D: -14 - 826 (UniProt: P19491)
A, B, C, D: 830 - 1034 (UniProt: Q8VHW4)
| PDB | External Database | Details |
|---|---|---|
| Glu 241 | Asn 256 | conflict |
| Leu 382 | Val 397 | conflict |
| - | Leu 399 | deletion |
| - | Thr 400 | deletion |
| - | Glu 401 | deletion |
| - | Leu 402 | deletion |
| - | Pro 403 | deletion |
| - | Ser 404 | deletion |
| Glu 384 | Gly 405 | conflict |
| Asp 385 | Asn 406 | conflict |
| Gln 392 | Asn 413 | conflict |
| Gly 827 | - | linker |
| Thr 828 | - | linker |
| Gly 829 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 503375.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1549.9 | |
| All* | Total formula weight | 504925.5 |
