11SU

Structure of Yarrowia lipolytica ORC-Cdc6 bound to 60bp segment of OriA-006 DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Origin recognition complex subunit 1 (Orc1)	polymer	861	96564.9	1	UniProt (Q6C9L7)	Yarrowia lipolytica
2	B (B)	Origin recognition complex subunit 2 (Orc2)	polymer	509	57479.1	1	UniProt (Q6C865)	Yarrowia lipolytica
3	C (C)	Origin recognition complex subunit 3 (Orc3)	polymer	685	78749.5	1	UniProt (Q6C1N4)	Yarrowia lipolytica	YALI0F14773p
4	D (D)	Origin recognition complex subunit 4 (Orc4)	polymer	511	57684.3	1	UniProt (Q6C5R0)	Yarrowia lipolytica
5	E (E)	Origin recognition complex subunit 5 (Orc5)	polymer	465	52939.5	1	UniProt (Q6CG25)	Yarrowia lipolytica	YALI0B01452p
6	F (F)	Origin recognition complex subunit 6 (Orc6)	polymer	365	41218.4	1	UniProt (Q6BZQ7)	Yarrowia lipolytica	YALI0F31647p
7	G, J, K (G, K, L)	Cell division control protein 6 (Cdc6)	polymer	605	66907.1	3	UniProt (Q6CDG7)	Yarrowia lipolytica
8	H (X)	DNA (60-MER)	polymer	60	18255.7	1		Yarrowia lipolytica
9	I (Y)	DNA (60-MER)	polymer	60	18730.9	1		Yarrowia lipolytica
10	L, O, P, R (A, D, E, G)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG) PubChem (888)
11	M, N, Q, S (A, D, E, G)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	4	Chemie (ATP)
12	T, U, V, W, X... (A, C, D, E, G...)	water	water		18.0	55	Chemie (HOH)

Sequence modifications

A: 1 - 718 (UniProt: Q6C9L7)

PDB	External Database	Details
Met -142	-	initiating methionine
Ser -141	-	expression tag
Ala -140	-	expression tag
Trp -139	-	expression tag
Ser -138	-	expression tag
His -137	-	expression tag
Pro -136	-	expression tag
Gln -135	-	expression tag
Phe -134	-	expression tag
Glu -133	-	expression tag
Lys -132	-	expression tag
Gly -131	-	expression tag
Gly -130	-	expression tag
Gly -129	-	expression tag
Ser -128	-	expression tag
Gly -127	-	expression tag
Gly -126	-	expression tag
Gly -125	-	expression tag
Ser -124	-	expression tag
Gly -123	-	expression tag
Gly -122	-	expression tag
Ser -121	-	expression tag
Ala -120	-	expression tag
Trp -119	-	expression tag
Ser -118	-	expression tag
His -117	-	expression tag
Pro -116	-	expression tag
Gln -115	-	expression tag
Phe -114	-	expression tag
Glu -113	-	expression tag
Lys -112	-	expression tag
Thr -111	-	expression tag
Gly -110	-	expression tag
Ser -109	-	expression tag
Leu -108	-	expression tag
Gln -107	-	expression tag
Asp -106	-	expression tag
Ser -105	-	expression tag
Glu -104	-	expression tag
Val -103	-	expression tag
Asn -102	-	expression tag
Gln -101	-	expression tag
Glu -100	-	expression tag
Ala -99	-	expression tag
Lys -98	-	expression tag
Pro -97	-	expression tag
Glu -96	-	expression tag
Val -95	-	expression tag
Lys -94	-	expression tag
Pro -93	-	expression tag
Glu -92	-	expression tag
Val -91	-	expression tag
Lys -90	-	expression tag
Pro -89	-	expression tag
Glu -88	-	expression tag
Thr -87	-	expression tag
His -86	-	expression tag
Ile -85	-	expression tag
Asn -84	-	expression tag
Leu -83	-	expression tag
Lys -82	-	expression tag
Val -81	-	expression tag
Ser -80	-	expression tag
Asp -79	-	expression tag
Gly -78	-	expression tag
Ser -77	-	expression tag
Ser -76	-	expression tag
Glu -75	-	expression tag
Ile -74	-	expression tag
Phe -73	-	expression tag
Phe -72	-	expression tag
Lys -71	-	expression tag
Ile -70	-	expression tag
Lys -69	-	expression tag
Lys -68	-	expression tag
Thr -67	-	expression tag
Thr -66	-	expression tag
Pro -65	-	expression tag
Leu -64	-	expression tag
Arg -63	-	expression tag
Arg -62	-	expression tag
Leu -61	-	expression tag
Met -60	-	expression tag
Glu -59	-	expression tag
Ala -58	-	expression tag
Phe -57	-	expression tag
Ala -56	-	expression tag
Lys -55	-	expression tag
Arg -54	-	expression tag
Gln -53	-	expression tag
Gly -52	-	expression tag
Lys -51	-	expression tag
Glu -50	-	expression tag
Met -49	-	expression tag
Asp -48	-	expression tag
Ser -47	-	expression tag
Leu -46	-	expression tag
Thr -45	-	expression tag
Phe -44	-	expression tag
Leu -43	-	expression tag
Tyr -42	-	expression tag
Asp -41	-	expression tag
Gly -40	-	expression tag
Ile -39	-	expression tag
Glu -38	-	expression tag
Ile -37	-	expression tag
Gln -36	-	expression tag
Ala -35	-	expression tag
Asp -34	-	expression tag
Gln -33	-	expression tag
Thr -32	-	expression tag
Pro -31	-	expression tag
Glu -30	-	expression tag
Asp -29	-	expression tag
Leu -28	-	expression tag
Asp -27	-	expression tag
Met -26	-	expression tag
Glu -25	-	expression tag
Asp -24	-	expression tag
Asn -23	-	expression tag
Asp -22	-	expression tag
Ile -21	-	expression tag
Ile -20	-	expression tag
Glu -19	-	expression tag
Ala -18	-	expression tag
His -17	-	expression tag
Arg -16	-	expression tag
Glu -15	-	expression tag
Gln -14	-	expression tag
Ile -13	-	expression tag
Gly -12	-	expression tag
Gly -11	-	expression tag
Ile -10	-	expression tag
Pro -9	-	expression tag
Thr -8	-	expression tag
Thr -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag

D: 1 - 511 (UniProt: Q6C5R0)

PDB	External Database	Details
Glu 18	Lys 18	conflict

G, K, L: 1 - 604 (UniProt: Q6CDG7)

PDB	External Database	Details
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	11
	Total formula weight	622343.8
Non-Polymers*	Number of molecules	8
	Total formula weight	2125.9
All*	Total formula weight	624469.7

*Water molecules are not included.