11OP
Crystal Structure of M. tuberculosis ClpP1P2 bound to ONC201
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | ATP-dependent Clp protease proteolytic subunit 2 | polymer | 214 | 23650.9 | 7 | UniProt (P9WPC3) Pfam (PF00574) | Mycobacterium tuberculosis H37Rv | Endopeptidase Clp 2 |
| 2 | H, I, J, K, L... (H, I, J, K, L...) | ATP-dependent Clp protease proteolytic subunit 1 | polymer | 194 | 21065.9 | 7 | UniProt (P9WPC5) Pfam (PF00574) | Mycobacterium tuberculosis H37Rv | Endopeptidase Clp 1 |
| 3 | GA, MA, O, TA, U... (D, E, A, F, B...) | BENZOIC ACID | non-polymer | 122.1 | 7 | Chemie (BEZ) | |||
| 4 | AA, AB, BA, HA, IA... (C, G, D, E, A...) | LEUCINE | non-polymer | 131.2 | 14 | Chemie (LEU) PubChem (6106) | |||
| 5 | BB, CA, EB, FB, GB... (G, C, H, I, J...) | Dordaviprone | non-polymer | 386.5 | 14 | Chemie (A1C98) | |||
| 6 | DB, FA, KA, QA, S... (G, C, D, E, A...) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 7 | Chemie (DMS) PubChem (679) | |||
| 7 | LA, T (D, A) | 2-(2-ETHOXYETHOXY)ETHANOL | non-polymer | 134.2 | 2 | Chemie (AE3) PubChem (8146) | |||
| 8 | DA (C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) PubChem (8117) | |||
| 9 | EA (C) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) PubChem (8200) | |||
| 10 | SA (E) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 11 | CB, WA (G, F) | 2-(2-METHOXYETHOXY)ETHANOL | non-polymer | 120.1 | 2 | Chemie (PG0) PubChem (8134) | |||
| 12 | LB, MB, NB, OB, PB... (A, B, C, D, E...) | water | water | 18.0 | 74 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G: 13 - 214 (UniProt: P9WPC3)
| PDB | External Database | Details |
|---|---|---|
| Met 12 | - | initiating methionine |
| Ala 215 | - | expression tag |
| Ala 216 | - | expression tag |
| Ala 217 | - | expression tag |
| Leu 218 | - | expression tag |
| Glu 219 | - | expression tag |
| His 220 | - | expression tag |
| His 221 | - | expression tag |
| His 222 | - | expression tag |
| His 223 | - | expression tag |
| His 224 | - | expression tag |
| His 225 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 14 |
| Total formula weight | 313017.9 | |
| Non-Polymers* | Number of molecules | 49 |
| Total formula weight | 9608.2 | |
| All* | Total formula weight | 322626.1 |
