11OI
Cryo-EM structure of human DNMT3A homo-hexamer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (C, E, F, D, A...) | DNA (cytosine-5)-methyltransferase 3A | polymer | 633 | 72297.8 | 6 | UniProt (Q9Y6K1) Pfam (PF00855) Pfam (PF17980) Pfam (PF21255) Pfam (PF00145) | Homo sapiens (human) | Dnmt3a,Cysteine methyltransferase DNMT3A,DNA methyltransferase HsaIIIA,DNA MTase HsaIIIA,M.HsaIIIA |
| 2 | G, K, O, S (C, D, A, B) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 4 | Chemie (SAH) PubChem (439155) | |||
| 3 | H, I, J, L, M... (C, D, A, B) | ZINC ION | non-polymer | 65.4 | 12 | Chemie (ZN) PubChem (32051) |
Sequence modifications
C, E, F, D, A, B: 281 - 912 (UniProt: Q9Y6K1)
| PDB | External Database | Details |
|---|---|---|
| Ser 280 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 433786.8 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2322.6 | |
| All* | Total formula weight | 436109.3 |
