11MG
Cryo-EM Structure of Human C3 Pro-Convertase bound to the Compstatin Analog Cp60, TED Conformation 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Complement C3 beta chain | polymer | 645 | 71393.3 | 1 | UniProt (P01024) | Homo sapiens (human) | |
| 2 | B (B) | Complement C3b alpha' chain | polymer | 915 | 104073.2 | 1 | UniProt (P01024) | Homo sapiens (human) | |
| 3 | C (C) | Compstatin Cp60 | polymer | 16 | 2066.5 | 1 | synthetic construct | ||
| 4 | D (D) | Complement factor B | polymer | 739 | 83109.8 | 1 | UniProt (P00751) | Homo sapiens (human) | C3/C5 convertase,Glycine-rich beta glycoprotein,GBG,PBF2,Properdin factor B |
| 5 | E, F (E, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 6 | G, H (A, D) | NICKEL (II) ION | non-polymer | 58.7 | 2 | Chemie (NI) PubChem (934) | |||
| 7 | I, J (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) PubChem (24139) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 260642.7 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 559.8 | |
| All* | Total formula weight | 262051.3 |
