11LZ
Crystal structure of Interferon alpha2 bound to IFA001 Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Interferon alpha-2 | polymer | 194 | 22396.8 | 2 | UniProt (P01563) | Homo sapiens (human) | IFN-alpha-2,Interferon alpha-A,LeIF A |
| 2 | C, F (C, L) | IFA001 Fab light chain | polymer | 216 | 23009.6 | 2 | Homo sapiens | ||
| 3 | D, E (D, H) | IFA001 Fab heavy chain | polymer | 230 | 24566.3 | 2 | Homo sapiens | ||
| 4 | G, H (D, H) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) PubChem (24139) |
Sequence modifications
A, B: -22 - 165 (UniProt: P01563)
| PDB | External Database | Details |
|---|---|---|
| Glu 166 | - | expression tag |
| Asn 167 | - | expression tag |
| Leu 168 | - | expression tag |
| Tyr 169 | - | expression tag |
| Phe 170 | - | expression tag |
| Gln 171 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 139945.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 442.4 | |
| All* | Total formula weight | 140387.9 |
