11GL
Crystal structure of mSTING in complex with 2'3'-cUMP-AMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Stimulator of interferon genes protein | polymer | 185 | 21173.0 | 2 | UniProt (Q3TBT3) Pfam (PF15009) | Mus musculus (house mouse) | mSTING,Endoplasmic reticulum interferon stimulator,ERIS,Mediator of IRF3 activation,MMITA,Transmembrane protein 173 |
| 2 | C (A) | 2'3'-cUA | non-polymer | 635.4 | 1 | Chemie (ZNT) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 34 | Chemie (HOH) |
Sequence modifications
A, B: 153 - 336 (UniProt: Q3TBT3)
| PDB | External Database | Details |
|---|---|---|
| Ser 152 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42346.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 635.4 | |
| All* | Total formula weight | 42981.4 |
