11EV
Cryo-EM structure of a bovine CLC-K S68N/R355K chloride channel with inhibitor P-BIM15
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Chloride voltage-gated channel Ka | polymer | 671 | 73520.5 | 2 | UniProt (E1B792) | Bos taurus (domestic cattle) | |
| 2 | C, F (A, B) | (1M)-6-chloro-1-(3-chloro[1,1'-biphenyl]-4-yl)-1H-1,3-benzimidazole-2-sulfonic acid | non-polymer | 419.3 | 2 | Chemie (A1C8L) | |||
| 3 | D, E, G, H (A, B) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) PubChem (312) |
Sequence modifications
A, B: 27 - 687 (UniProt: E1B792)
| PDB | External Database | Details |
|---|---|---|
| Met 26 | - | initiating methionine |
| Asn 68 | Ser 68 | engineered mutation |
| Lys 355 | Arg 355 | engineered mutation |
| Gln 373 | Asn 373 | engineered mutation |
| Ser 688 | - | expression tag |
| Asn 689 | - | expression tag |
| Ser 690 | - | expression tag |
| Leu 691 | - | expression tag |
| Glu 692 | - | expression tag |
| Val 693 | - | expression tag |
| Leu 694 | - | expression tag |
| Phe 695 | - | expression tag |
| Gln 696 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 147041.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 980.4 | |
| All* | Total formula weight | 148021.4 |
