11DC
Human Slo1-PenitremA complex under divalent chelated condition - gating-ring masked out
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Isoform 5 of Calcium-activated potassium channel subunit alpha-1 | polymer | 1065 | 119970.0 | 4 | UniProt (Q12791) | Homo sapiens (human) | BK channel,BKCA alpha,Calcium-activated potassium channel,subfamily M subunit alpha-1,K(VCA)alpha,KCa1.1,Maxi K channel,MaxiK,Slo-alpha,Slo1,Slowpoke homolog,Slo homolog,hSlo |
| 2 | E, F, G, H, I (A) | POTASSIUM ION | non-polymer | 39.1 | 5 | Chemie (K) PubChem (813) | |||
| 3 | DC, EC, FB, FC, GB... (D, C, B, A) | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine | non-polymer | 760.1 | 32 | Chemie (LBN) | |||
| 4 | AA, AB, AC, BA, BB... (A, B, C, D) | Digitonin | non-polymer | 1229.3 | 32 | Chemie (AJP) PubChem (6474107) | |||
| 5 | IC, JC, KB, KC, LB... (D, C, B, A) | CHOLESTEROL | non-polymer | 386.7 | 28 | Chemie (CLR) PubChem (5997) | |||
| 6 | AD, CC, EB, HA (D, C, B, A) | Penitrem A | non-polymer | 634.2 | 4 | Chemie (A1C9J) | |||
| 7 | BD, CD, DD, ED (A, B, C, D) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 1056 (UniProt: Q12791)
| PDB | External Database | Details |
|---|---|---|
| Ile 513 | Met 578 | engineered mutation |
| Ser 1057 | - | expression tag |
| Asn 1058 | - | expression tag |
| Ser 1059 | - | expression tag |
| Leu 1060 | - | expression tag |
| Glu 1061 | - | expression tag |
| Val 1062 | - | expression tag |
| Leu 1063 | - | expression tag |
| Phe 1064 | - | expression tag |
| Gln 1065 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 479880.1 | |
| Non-Polymers* | Number of molecules | 101 |
| Total formula weight | 77219.0 | |
| All* | Total formula weight | 557099.1 |
