11BK

Crystal structure of radiolytically cleaved trabectedin-DNA complex

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (E, F)	12-mer double-stranded DNA	polymer	12	3646.4	2		synthetic construct
2	C, D (E, F)	[(6aS,7R,13S,14S,15S,16R)-5-(acetyloxy)-8,14-dihydroxy-9-methoxy-4,10,17-trimethyl-6,7,12,13,14,16-hexahydro-2H,6aH-7,13-epimino[1,3]dioxolo[7,8]isoquinolino[3,2-b][3]benzazocin-16-yl]methyl (1R)-6-hydroxy-7-methoxy-1-(sulfanylmethyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxylate	non-polymer		763.9	2	Chemie (A1DET)
3	E, F (E, F)	water	water		18.0	49	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	7292.8
Non-Polymers*	Number of molecules	2
	Total formula weight	1527.7
All*	Total formula weight	8820.5

*Water molecules are not included.