10YH
DNA Ligase IIIa bound to a nucleosome containing a nick at SHL-6 (composite)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, E) | Histone H3.2 | polymer | 97 | 11385.3 | 2 | UniProt (Q71DI3) Pfam (PF00125) | Homo sapiens (human) | H3-clustered histone 13,H3-clustered histone 14,H3-clustered histone 15,Histone H3/m,Histone H3/o |
| 2 | B, F (B, F) | Histone H4 | polymer | 80 | 9123.7 | 2 | UniProt (P62805) Pfam (PF15511) | Homo sapiens (human) | |
| 3 | C, G (C, G) | Histone H2A type 1-H | polymer | 107 | 11692.7 | 2 | UniProt (Q96KK5) Pfam (PF00125) Pfam (PF16211) | Homo sapiens (human) | H2A-clustered histone 12,Histone H2A/s |
| 4 | D, H (D, H) | Histone H2B type 1-M | polymer | 93 | 10336.8 | 2 | UniProt (Q99879) Pfam (PF00125) | Homo sapiens (human) | Histone H2B.e,H2B/e |
| 5 | I (I) | 601 I strand (non-damaged strand) | polymer | 147 | 45138.8 | 1 | synthetic construct | ||
| 6 | J (J) | 601 J strand (damaged strand 1) | polymer | 15 | 4623.0 | 1 | synthetic construct | ||
| 7 | K (K) | 601 K strand (damaged strand 2) | polymer | 132 | 40942.1 | 1 | synthetic construct | ||
| 8 | L (L) | DNA ligase 3 | polymer | 208 | 23847.9 | 1 | UniProt (P49916) Pfam (PF01068) | Homo sapiens (human) | DNA ligase III,Polydeoxyribonucleotide synthase [ATP] 3 |
| 9 | M (L) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) PubChem (16397049) PubChem (16760266) PubChem (224) PubChem (34768) PubChem (83862) PubChem (40467049) PubChem (40469468) PubChem (446048) PubChem (44348067) PubChem (45358029) PubChem (40459109) PubChem (515384) PubChem (46874558) PubChem (638042) PubChem (46875232) PubChem (57358045) PubChem (57879893) PubChem (57879902) PubChem (5316444) PubChem (5742864) PubChem (177678969) PubChem (6083) PubChem (1549371) PubChem (12163610) PubChem (12358355) PubChem (92144436) PubChem (122197642) PubChem (12358354) PubChem (162290139) PubChem (162946266) PubChem (171699505) |
Sequence modifications
A, E: 38 - 134 (UniProt: Q71DI3)
| PDB | External Database | Details |
|---|---|---|
| Ala 110 | Cys 111 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 199628.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 347.2 | |
| All* | Total formula weight | 199975.9 |
