10YF
DNA Ligase IIIa bound to nucleosome containing a nick at SHL-2 (composite)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, E) | Histone H3.2 | polymer | 96 | 11228.1 | 2 | UniProt (Q71DI3) Pfam (PF00125) | Homo sapiens (human) | H3-clustered histone 13,H3-clustered histone 14,H3-clustered histone 15,Histone H3/m,Histone H3/o |
| 2 | B, F (B, F) | Histone H4 | polymer | 80 | 9123.7 | 2 | UniProt (P62805) Pfam (PF15511) | Homo sapiens (human) | |
| 3 | C, G (C, G) | Histone H2A type 1-H | polymer | 107 | 11692.7 | 2 | UniProt (Q96KK5) Pfam (PF00125) Pfam (PF16211) | Homo sapiens (human) | H2A-clustered histone 12,Histone H2A/s |
| 4 | D, H (D, H) | Histone H2B type 2-F | polymer | 92 | 10249.7 | 2 | UniProt (Q5QNW6) Pfam (PF00125) | Homo sapiens (human) | Histone H2B.e,H2B/e |
| 5 | I (I) | 601 I strand (non-damaged strand) | polymer | 147 | 45138.8 | 1 | synthetic construct | ||
| 6 | J (J) | 601 J strand (damaged strand 1) | polymer | 56 | 17352.1 | 1 | synthetic construct | ||
| 7 | K (K) | 601 K strand (damaged strand 2) | polymer | 91 | 28213.0 | 1 | synthetic construct | ||
| 8 | L (L) | DNA ligase 3 | polymer | 208 | 23847.9 | 1 | UniProt (P49916) Pfam (PF01068) | Homo sapiens (human) | DNA ligase III,Polydeoxyribonucleotide synthase [ATP] 3 |
| 9 | M (L) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) PubChem (6083) |
Sequence modifications
A, E: 38 - 133 (UniProt: Q71DI3)
| PDB | External Database | Details |
|---|---|---|
| Ala 110 | Cys 111 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 199140.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 347.2 | |
| All* | Total formula weight | 199487.4 |
