10TL
Cryo-EM structure of human MOR bound with DAMGO and BMS986187
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (R, F) | Mu-type opioid receptor | polymer | 388 | 43577.8 | 2 | UniProt (P35372) Pfam (PF00001) | Homo sapiens (human) | M-OR-1,MOR-1,Mu opiate receptor,Mu opioid receptor,MOP,hMOP |
| 2 | B, D (S, H) | TYR-DAL-GLY-MEA-ETA | polymer | 5 | 513.6 | 2 | BIRD (PRD_002308) | Homo sapiens | |
| 3 | E, F, G, I, J... (R, F) | CHOLESTEROL | non-polymer | 386.7 | 8 | Chemie (CLR) PubChem (5997) | |||
| 4 | H, N (R, F) | 3,3,6,6-tetramethyl-9-[4-[(2-methylphenyl)methoxy]phenyl]-4,5,7,9-tetrahydro-2~{H}-xanthene-1,8-dione | non-polymer | 470.6 | 2 | Chemie (A1D6B) PubChem (17379334) |
Sequence modifications
R, F: 1 - 388 (UniProt: P35372)
| PDB | External Database | Details |
|---|---|---|
| Trp 158 | Phe 158 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 88182.9 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 4034.4 | |
| All* | Total formula weight | 92217.3 |
