10OI
Structure of Clostridium difficile Toxin B (TcdB) glucosyltransferase in complex with UDP linked isofagomine analog 3-5
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Toxin B | polymer | 552 | 64313.8 | 2 | UniProt (P18177) | Clostridioides difficile | |
| 2 | C, F (A, B) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 2 | Chemie (UDP) | |||
| 3 | D, G (A, B) | 1-(5-O-{3-[(3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)piperidin-1-yl]propyl}-alpha-L-lyxofuranosyl)pyrimidine-2,4(1H,3H)-dione | non-polymer | 431.4 | 2 | Chemie (A1C96) | |||
| 4 | E, H (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) PubChem (27854) | |||
| 5 | I, J, K (B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) PubChem (753) | |||
| 6 | L, M (A, B) | water | water | 18.0 | 99 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 545 (UniProt: P18177)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | expression tag |
| Gly 1 | - | expression tag |
| Leu 544 | Gly 544 | conflict |
| His 546 | - | expression tag |
| His 547 | - | expression tag |
| His 548 | - | expression tag |
| His 549 | - | expression tag |
| His 550 | - | expression tag |
| His 551 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 128627.7 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2057.4 | |
| All* | Total formula weight | 130685.0 |
