10ND

Cryo-EM structure of human IL-10RA in complex with VHH E07

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Interleukin-10 receptor subunit alpha	polymer	227	25842.8	1	UniProt (Q13651) Pfam (PF01108)	Homo sapiens (human)	IL-10 receptor subunit alpha,IL-10R subunit alpha,IL-10RA,CDw210a,Interleukin-10 receptor subunit 1,IL-10R subunit 1,IL-10R1
2	B (B)	VHH antibody E07	polymer	132	14677.3	1		Lama glama
3	C, D (A, B)	water	water		18.0	24	Chemie (HOH)

Sequence modifications

A: 22 - 235 (UniProt: Q13651)

PDB	External Database	Details
Gly 236	-	expression tag
Gly 237	-	expression tag
Gly 238	-	expression tag
Gly 239	-	expression tag
Ser 240	-	expression tag
His 241	-	expression tag
His 242	-	expression tag
His 243	-	expression tag
His 244	-	expression tag
His 245	-	expression tag
His 246	-	expression tag
His 247	-	expression tag
His 248	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	40520.1
All*	Total formula weight	40520.1

*Water molecules are not included.