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10MG

CBR9379 bound Open2 Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with an open active site (open TL, SI3 and RH-FL)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(B)
template DNApolymer329706.31Escherichia coli
2B
(K)
DNA-directed RNA polymerase subunit omegapolymer9110249.51UniProt (P0A800)Escherichia coliRNAP omega subunit,RNA polymerase omega subunit,Transcriptase subunit omega
3C
(R)
RNApolymer196047.61Escherichia coli
4D
(A)
non-template DNApolymer329881.41Escherichia coli
5E, F
(G, H)
DNA-directed RNA polymerase subunit alphapolymer32936558.72UniProt (P0A7Z4)Escherichia coliRNAP subunit alpha,RNA polymerase subunit alpha,Transcriptase subunit alpha
6G
(I)
DNA-directed RNA polymerase subunit betapolymer1342150820.91UniProt (P0A8V2)Escherichia coliRNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta
7H
(J)
DNA-directed RNA polymerase subunit beta'polymer1407155366.81UniProt (P0A8T7)Escherichia coliRNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'
8I
(I)
CHAPSOnon-polymer631.91Chemie (1N7)
PubChem (90479263)
9J
(J)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
PubChem (888)
10K, L
(J)
ZINC IONnon-polymer65.42Chemie (ZN)
PubChem (32051)
11M
(J)
3-{[(2,6-dichlorophenyl)carbamoyl]amino}-N-hydroxy-N'-phenyl-5-(trifluoromethyl)benzenecarboximidamidenon-polymer483.31Chemie (42T)
12N, O, P, Q, R...
(B, K, R, A, G...)
waterwater18.0776Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight415189.8
Non-Polymers*Number of molecules5
Total formula weight1270.3
All*Total formula weight416460.1
*Water molecules are not included.

255615

PDB entries from 2026-06-24

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