10JZ

Structure of the human CHI3L1-LZ6 complex

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Chitinase-3-like protein 1	polymer	401	44839.7	4	UniProt (P36222)	Homo sapiens (human)	39 kDa synovial protein,Cartilage glycoprotein 39,CGP-39,GP-39,hCGP-39,YKL-40
2	E, F, G, H (E, F, G, H)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	4	In PDB GlyTouCan (G42666HT)
3	I, L (A, B)	DIMETHYL SULFOXIDE	non-polymer		78.1	2	Chemie (DMS) PubChem (679)
4	J, M, O, Q (A, B, C, D)	GLYCEROL	non-polymer		92.1	4	Chemie (GOL) PubChem (753)
5	K, N, P, R (A, B, C, D)	N-(1-ethyl-6-oxo-1,6-dihydropyrimidin-5-yl)-4-(2-methyl-4-oxoquinazolin-3(4H)-yl)benzamide	non-polymer		401.4	4	Chemie (A1DAW)
6	S, T, U, V (A, B, C, D)	water	water		18.0	149	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 383 (UniProt: P36222)

PDB	External Database	Details
Gly 145	Arg 145	variant
Leu 384	-	expression tag
Glu 385	-	expression tag
Val 386	-	expression tag
Leu 387	-	expression tag
Phe 388	-	expression tag
Gln 389	-	expression tag
Gly 390	-	expression tag
Pro 391	-	expression tag
His 392	-	expression tag
His 393	-	expression tag
His 394	-	expression tag
His 395	-	expression tag
His 396	-	expression tag
His 397	-	expression tag
His 398	-	expression tag
His 399	-	expression tag
His 400	-	expression tag
His 401	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	179358.8
Branched	Number of molecules	4
	Total formula weight	1697.6
Non-Polymers*	Number of molecules	10
	Total formula weight	2130.3
All*	Total formula weight	183186.7

*Water molecules are not included.