10FE
OX1-Germline in complex with GluN1-GluN2B, full refinement
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Glutamate receptor ionotropic, NMDA 1 | polymer | 844 | 94854.5 | 2 | UniProt (Q05586) | Homo sapiens (human) | GluN1,Glutamate [NMDA] receptor subunit zeta-1,N-methyl-D-aspartate receptor subunit NR1,NMD-R1,hNR1 |
| 2 | B, D (B, D) | Glutamate receptor ionotropic, NMDA 2B | polymer | 826 | 92886.0 | 2 | UniProt (Q13224) | Homo sapiens (human) | GluN2B,Glutamate [NMDA] receptor subunit epsilon-2,N-methyl D-aspartate receptor subtype 2B,NMDAR2B,NR2B,N-methyl-D-aspartate receptor subunit 3,NR3,hNR3 |
| 3 | E, G (F, H) | Heavy chain | polymer | 119 | 12991.3 | 2 | Homo sapiens | ||
| 4 | F, H (G, I) | Light chain | polymer | 113 | 11850.0 | 2 | Homo sapiens |
Sequence modifications
A, C: 1 - 838 (UniProt: Q05586)
B, D: 27 - 852 (UniProt: Q13224)
| PDB | External Database | Details |
|---|---|---|
| His 5 | Arg 5 | conflict |
| Phe 9 | Leu 9 | conflict |
| Phe 17 | Val 17 | conflict |
| Ser 22 | Cys 22 | conflict |
| Arg 212 | Lys 212 | conflict |
| Ile 267 | Leu 267 | conflict |
| Asn 556 | Gln 556 | conflict |
| Ile 819 | Leu 819 | conflict |
| Ser 839 | - | expression tag |
| Arg 840 | - | expression tag |
| Ala 841 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 271 | Ala 271 | conflict |
| Glu 437 | Gln 437 | conflict |
| Ser 588 | Cys 588 | conflict |
| Ser 838 | Cys 838 | conflict |
| Ser 849 | Cys 849 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 425163.6 | |
| All* | Total formula weight | 425163.6 |
