10EW
Catalytic domain of GH33 sialidase from Ruminococcus lactaris
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | exo-alpha-sialidase | polymer | 470 | 50413.7 | 1 | UniProt (V8BL81) | [Ruminococcus] lactaris | |
| 2 | B (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (A) | water | water | 18.0 | 517 | Chemie (HOH) |
Sequence modifications
A: 1 - 448 (UniProt: V8BL81)
| PDB | External Database | Details |
|---|---|---|
| His -21 | - | expression tag |
| His -20 | - | expression tag |
| His -19 | - | expression tag |
| His -18 | - | expression tag |
| His -17 | - | expression tag |
| His -16 | - | expression tag |
| Ser -15 | - | expression tag |
| Ser -14 | - | expression tag |
| Gly -13 | - | expression tag |
| Val -12 | - | expression tag |
| Asp -11 | - | expression tag |
| Leu -10 | - | expression tag |
| Gly -9 | - | expression tag |
| Thr -8 | - | expression tag |
| Glu -7 | - | expression tag |
| Asn -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Tyr -4 | - | expression tag |
| Phe -3 | - | expression tag |
| Gln -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Asn 0 | - | expression tag |
| Ile 44 | Val 71 | conflict |
| Val 111 | Ala 138 | conflict |
| Glu 163 | Ala 190 | conflict |
| Ala 177 | Thr 204 | conflict |
| Met 227 | Val 254 | conflict |
| Glu 239 | Asp 266 | conflict |
| Ser 265 | Thr 292 | conflict |
| Tyr 279 | Phe 306 | conflict |
| Ser 281 | Asn 308 | conflict |
| Leu 307 | Phe 334 | conflict |
| Gly 389 | Val 416 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 50413.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 188.2 | |
| All* | Total formula weight | 50601.9 |
