10CR

Crystal structure of the complex between human PTPRD and TeNT

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Tetanus toxin	polymer	886	101398.0	1	UniProt (P04958) Pfam (PF01742) Pfam (PF07952)	Clostridium tetani	Tentoxylysin
2	B (B)	Receptor-type tyrosine-protein phosphatase delta	polymer	310	34145.6	1	UniProt (P23468) Pfam (PF07679) Pfam (PF13927)	Homo sapiens (human)	Protein-tyrosine phosphatase delta,R-PTP-delta
3	C (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN) PubChem (32051)
4	D, E (A, B)	water	water		18.0	11	Chemie (HOH)

Sequence modifications

A: 1 - 443 (UniProt: P04958)

PDB	External Database	Details
Phe 375	Tyr 375	conflict

A: 443 - 870 (UniProt: P04958)

PDB	External Database	Details
Ala 443	-	linker
Ser 443	-	linker
Leu 443	-	linker
Val 443	-	linker
Pro 443	-	linker
Arg 443	-	linker
Gly 443	-	linker
Ser 443	-	linker
Gly 443	-	linker
Ser 443	-	linker
Leu 871	-	expression tag
Pro 872	-	expression tag
Glu 873	-	expression tag
Thr 874	-	expression tag
Gly 875	-	expression tag
Gly 876	-	expression tag
Leu 877	-	expression tag
Glu 878	-	expression tag
His 879	-	expression tag
His 880	-	expression tag
His 881	-	expression tag
His 882	-	expression tag
His 883	-	expression tag
His 884	-	expression tag

B: 21 - 321 (UniProt: P23468)

PDB	External Database	Details
Gly 322	-	expression tag
Thr 323	-	expression tag
Lys 324	-	expression tag
His 325	-	expression tag
His 326	-	expression tag
His 327	-	expression tag
His 328	-	expression tag
His 329	-	expression tag
His 330	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	135543.5
Non-Polymers*	Number of molecules	1
	Total formula weight	65.4
All*	Total formula weight	135608.9

*Water molecules are not included.