10BE
Human AGO2 bound to a miR-20a guide and a position 10-11 mismatched target
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Guide RNA | polymer | 23 | 7429.4 | 1 | Homo sapiens | ||
| 2 | B (C) | Target RNA | polymer | 18 | 5684.5 | 1 | Homo sapiens | ||
| 3 | C (A) | Protein argonaute-2 | polymer | 873 | 98881.8 | 1 | UniProt (Q9UKV8) | Homo sapiens (human) | Argonaute2,hAgo2,Argonaute RISC catalytic component 2,Eukaryotic translation initiation factor 2C 2,eIF-2C 2,eIF2C 2,PAZ Piwi domain protein,PPD,Protein slicer |
Sequence modifications
A: 1 - 859 (UniProt: Q9UKV8)
| PDB | External Database | Details |
|---|---|---|
| Gly -13 | - | expression tag |
| Ala -12 | - | expression tag |
| Met -11 | - | expression tag |
| Gly -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Met -8 | - | expression tag |
| Asp -7 | - | expression tag |
| Tyr -6 | - | expression tag |
| Lys -5 | - | expression tag |
| Asp -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Asp -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Lys 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 111995.7 | |
| All* | Total formula weight | 111995.7 |
