10AF

Crystal Structure of cyclophilin B, from Brugia malayi (K5H/S166A mutant)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Peptidyl-prolyl cis-trans isomerase	polymer	179	19535.2	1	UniProt (A0A0J9XUF2) Pfam (PF00160)	Brugia malayi	PPIase
2	B, C, D (A)	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
3	E, F, G (A)	CHLORIDE ION	non-polymer		35.5	3	Chemie (CL)
4	H (A)	water	water		18.0	245	Chemie (HOH)

Sequence modifications

A: 1 - 171 (UniProt: A0A0J9XUF2)

PDB	External Database	Details
Met -7	-	initiating methionine
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 5	Lys 5	engineered mutation
Ala 166	Ser 166	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	19535.2
Non-Polymers*	Number of molecules	6
	Total formula weight	394.5
All*	Total formula weight	19929.7

*Water molecules are not included.