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10AD

Cryo-EM structure of the human BK channel bound to the agonist NS1619

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(E, C, D, A)
Isoform 5 of Calcium-activated potassium channel subunit alpha-1polymer1113125343.74UniProt (Q12791)Homo sapiens (human)BK channel,BKCA alpha,Calcium-activated potassium channel,subfamily M subunit alpha-1,K(VCA)alpha,KCa1.1,Maxi K channel,MaxiK,Slo-alpha,Slo1,Slowpoke homolog,Slo homolog,hSlo
2E, I, M, Q
(E, C, D, A)
MAGNESIUM IONnon-polymer24.34Chemie (MG)
3F, G, J, K, N...
(E, C, D, A)
CALCIUM IONnon-polymer40.18Chemie (CA)
4H, L, P, T
(E, C, D, A)
3-[2-oxidanyl-5-(trifluoromethyl)phenyl]-6-(trifluoromethyl)-1~{H}-benzimidazol-2-onenon-polymer362.24Chemie (A1E02)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight501374.9
Non-Polymers*Number of molecules16
Total formula weight1866.8
All*Total formula weight503241.7
*Water molecules are not included.

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PDB entries from 2026-02-11

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