1WJ9
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CRYSTAL STRUCTURE OF A CRISPR-ASSOCIATED PROTEIN FROM THERMUS THERMOPHILUS
Descriptor:CRISPR-associated protein
Authors:Ebihara, A., Yao, M., Yokoyama, S., Kuramitsu, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-05-29
Release date:2004-11-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of hypothetical protein TTHB192 from Thermus thermophilus HB8 reveals a new protein family with an RNA recognition motif-like domain
Protein Sci., 15, 2006
2Y8W
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STRUCTURE OF CRISPR ENDORIBONUCLEASE CSE3 BOUND TO 20 NT RNA
Descriptor:5'-R(*UP*CP*CP*CP*CP*AP*CP*GP*CP*GP*UP*GP*UP*GP *GP*GP*DGP*AP*UP*G)-3', CSE3
Authors:Sashital, D.G., Jinek, M., Doudna, J.A.
Deposit date:2011-02-11
Release date:2011-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:An RNA-Induced Conformational Change Required for Crispr RNA Cleavage by the Endoribonuclease Cse3.
Nat.Struct.Mol.Biol., 18, 2011
2Y8Y
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STRUCTURE B OF CRISPR ENDORIBONUCLEASE CSE3 BOUND TO 19 NT RNA
Descriptor:5'-R(*UP*CP*CP*CP*CP*AP*CP*GP*CP*GP*UP*GP*UP*GP *GP*GP*DGP*AP*U)-3', CSE3
Authors:Sashital, D.G., Jinek, M., Doudna, J.A.
Deposit date:2011-02-11
Release date:2011-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:An RNA-Induced Conformational Change Required for Crispr RNA Cleavage by the Endoribonuclease Cse3.
Nat.Struct.Mol.Biol., 18, 2011
2Y9H
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STRUCTURE A OF CRISPR ENDORIBONUCLEASE CSE3 BOUND TO 19 NT RNA
Descriptor:5'-R(*UP*CP*CP*CP*CP*AP*CP*GP*CP*GP*UP*GP*UP*GP *GP*GP*DGP*AP*UP)-3', CSE3
Authors:Sashital, D.G., Jinek, M., Doudna, J.A.
Deposit date:2011-02-14
Release date:2011-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An RNA-Induced Conformational Change Required for Crispr RNA Cleavage by the Endoribonuclease Cse3.
Nat.Struct.Mol.Biol., 18, 2011
3QRP
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STRUCTURE OF THERMUS THERMOPHILUS CSE3 BOUND TO AN RNA REPRESENTING A PRODUCT MIMIC COMPLEX
Descriptor:Putative uncharacterized protein TTHB192, RNA (5'-R(*GP*UP*CP*CP*CP*CP*AP*CP*(PGP))-3'), RNA (5'-R(P*(U5P)P*GP*UP*GP*GP*GP*G)-3'), ...
Authors:Schellenberg, M.J., Gesner, E.M., Garside, E.L., MacMillan, A.M.
Deposit date:2011-02-18
Release date:2011-05-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.352 Å)
Cite:Recognition and maturation of effector RNAs in a CRISPR interference pathway.
Nat.Struct.Mol.Biol., 18, 2011
3QRQ
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STRUCTURE OF THERMUS THERMOPHILUS CSE3 BOUND TO AN RNA REPRESENTING A PRE-CLEAVAGE COMPLEX
Descriptor:Putative uncharacterized protein TTHB192, RNA (5'-R(*GP*UP*CP*CP*CP*CP*AP*CP*GP*CP*GP*UP*GP*UP*GP*GP*GP*GP*A)-3')
Authors:Schellenberg, M.J., Gesner, E.G., Garside E.L., MacMillan, A.M.
Deposit date:2011-02-18
Release date:2011-05-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.194 Å)
Cite:Recognition and maturation of effector RNAs in a CRISPR interference pathway.
Nat.Struct.Mol.Biol., 18, 2011
3QRR
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STRUCTURE OF THERMUS THERMOPHILUS CSE3 BOUND TO AN RNA REPRESENTING A PRODUCT COMPLEX
Descriptor:Putative uncharacterized protein TTHB192, RNA (5'-R(*GP*UP*CP*CP*CP*CP*AP*CP*GP*CP*GP*UP*GP*UP*GP*GP*GP*(23G))-3')
Authors:Schellenberg, M.J., Gesner, E.G., Garside E.L., MacMillan, A.M.
Deposit date:2011-02-18
Release date:2011-05-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.099 Å)
Cite:Recognition and maturation of effector RNAs in a CRISPR interference pathway.
Nat.Struct.Mol.Biol., 18, 2011
4DZD
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CRYSTAL STRUCTURE OF THE CRISPR-ASSOCIATED PROTEIN CAS6E FROM ESCHERICHIA COLI STR. K-12
Descriptor:GLYCEROL, Uncharacterized protein ygcH
Authors:Wei, J., Huang, G., Wang, Y., Gong, W.
Deposit date:2012-03-01
Release date:2013-03-06
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Crystal Structure of endoribonuclease Cas6e from Escherichia coli
To be Published
4QYZ
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CRYSTAL STRUCTURE OF A CRISPR RNA-GUIDED SURVEILLANCE COMPLEX, CASCADE, BOUND TO A SSDNA TARGET
Descriptor:CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR system Cascade subunit CasC, ...
Authors:Mulepati, S., Bailey, S.
Deposit date:2014-07-26
Release date:2014-09-03
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (3.0303 Å)
Cite:Structural biology. Crystal structure of a CRISPR RNA-guided surveillance complex bound to a ssDNA target.
Science, 345, 2014
4TVX
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CRYSTAL STRUCTURE OF THE E. COLI CRISPR RNA-GUIDED SURVEILLANCE COMPLEX, CASCADE
Descriptor:CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR system Cascade subunit CasC, ...
Authors:Jackson, R.N., Golden, S.M., Carter, J., Wiedenheft, B.
Deposit date:2014-06-28
Release date:2014-08-13
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:Structural biology. Crystal structure of the CRISPR RNA-guided surveillance complex from Escherichia coli.
Science, 345, 2014
4U7U
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CRYSTAL STRUCTURE OF RNA-GUIDED IMMUNE CASCADE COMPLEX FROM E.COLI
Descriptor:CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR system Cascade subunit CasC, ...
Authors:Zhao, H., Sheng, G., Wang, J., Wang, M., Bunkoczi, G., Gong, W., Wei, Z., Wang, Y.
Deposit date:2014-07-31
Release date:2014-08-27
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (3.003 Å)
Cite:Crystal structure of the RNA-guided immune surveillance Cascade complex in Escherichia coli
Nature, 515, 2014
5CD4
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THE TYPE IE CRISPR CASCADE COMPLEX FROM E. COLI, WITH TWO ASSEMBLIES IN THE ASYMMETRIC UNIT ARRANGED BACK-TO-BACK
Descriptor:CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR system Cascade subunit CasC, ...
Authors:Jackson, R.N., Golden, S.M., Carter, J., Wiedenheft, B.
Deposit date:2015-07-03
Release date:2015-08-26
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Mechanism of CRISPR-RNA guided recognition of DNA targets in Escherichia coli.
Nucleic Acids Res., 43, 2015
5H9E
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CRYSTAL STRUCTURE OF E. COLI CASCADE BOUND TO A PAM-CONTAINING DSDNA TARGET (32-NT SPACER) AT 3.20 ANGSTROM RESOLUTION.
Descriptor:CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR system Cascade subunit CasC, ...
Authors:Hayes, R.P., Xiao, Y., Ding, F., van Erp, P.B.G., Rajashankar, K., Bailey, S., Wiedenheft, B., Ke, A.
Deposit date:2015-12-28
Release date:2016-02-17
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Structural basis for promiscuous PAM recognition in type I-E Cascade from E. coli.
Nature, 530, 2016
5H9F
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CRYSTAL STRUCTURE OF E. COLI CASCADE BOUND TO A PAM-CONTAINING DSDNA TARGET AT 2.45 ANGSTROM RESOLUTION.
Descriptor:CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR system Cascade subunit CasC, ...
Authors:Hayes, R.P., Xiao, Y., Ding, F., van Erp, P.B.G., Rajashankar, K., Bailey, S., Wiedenheft, B., Ke, A.
Deposit date:2015-12-28
Release date:2016-02-17
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural basis for promiscuous PAM recognition in type I-E Cascade from E. coli.
Nature, 530, 2016
5U07
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CRISPR RNA-GUIDED SURVEILLANCE COMPLEX
Descriptor:CRISPR-associated protein, Cas5e family, Cse1 family, ...
Authors:Xiao, Y., Luo, M., Hayes, R.P., Kim, J., Ng, S., Ding, F., Liao, M., Ke, A.
Deposit date:2016-11-23
Release date:2017-08-09
Last modified:2017-08-16
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure Basis for Directional R-loop Formation and Substrate Handover Mechanisms in Type I CRISPR-Cas System.
Cell, 170, 2017
5U0A
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CRISPR RNA-GUIDED SURVEILLANCE COMPLEX
Descriptor:CRISPR-associated protein, Cas5e family, Cse1 family, ...
Authors:Xiao, Y., Luo, M., Hayes, R.P., Kim, J., Ng, S., Ding, F., Liao, M., Ke, A.
Deposit date:2016-11-23
Release date:2017-08-09
Last modified:2017-08-16
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure Basis for Directional R-loop Formation and Substrate Handover Mechanisms in Type I CRISPR-Cas System.
Cell, 170, 2017
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