2HNH
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CRYSTAL STRUCTURE OF THE CATALYTIC ALPHA SUBUNIT OF E. COLI REPLICATIVE DNA POLYMERASE III
Descriptor:DNA polymerase III alpha subunit, PHOSPHATE ION
Authors:Meindert, M.H., Georgescu, R.E., Lee, S., O'Donnell, M., Kuriyan, J.
Deposit date:2006-07-12
Release date:2006-09-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of the Catalytic alpha Subunit of E. coli Replicative DNA Polymerase III.
Cell(Cambridge,Mass.), 126, 2006
2HPI
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EUBACTERIAL AND EUKARYOTIC REPLICATIVE DNA POLYMERASES ARE NOT HOMOLOGOUS: X-RAY STRUCTURE OF DNA POLYMERASE III
Descriptor:DNA polymerase III alpha subunit, ZINC ION, MAGNESIUM ION, ...
Authors:Bailey, S., Wing, R.A., Steitz, T.A.
Deposit date:2006-07-17
Release date:2006-09-19
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Structure of T. aquaticus DNA Polymerase III Is Distinct from Eukaryotic Replicative DNA Polymerases.
Cell(Cambridge,Mass.), 126, 2006
2HPM
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EUBACTERIAL AND EUKARYOTIC REPLICATIVE DNA POLYMERASES ARE NOT HOMOLOGOUS: X-RAY STRUCTURE OF DNA POLYMERASE III
Descriptor:DNA Polymerase III alpha subunit, ZINC ION, MAGNESIUM ION, ...
Authors:Bailey, S., Wing, R.A., Steitz, T.A.
Deposit date:2006-07-17
Release date:2006-09-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:The Structure of T. aquaticus DNA Polymerase III Is Distinct from Eukaryotic Replicative DNA Polymerases.
Cell(Cambridge,Mass.), 126, 2006
2HQA
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CRYSTAL STRUCTURE OF THE CATALYTIC ALPHA SUBUNIT OF E. COLI REPLICATIVE DNA POLYMERASE III
Descriptor:DNA polymerase III alpha subunit, PHOSPHATE ION
Authors:Lamers, M.H., Georgescu, R.E., Lee, S.G., O'Donnell, M., Kuriyan, J.
Deposit date:2006-07-18
Release date:2006-09-19
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the Catalytic alpha Subunit of E. coli Replicative DNA Polymerase III.
Cell(Cambridge,Mass.), 126, 2006
3E0D
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INSIGHTS INTO THE REPLISOME FROM THE CRYSTRAL STRUCTURE OF THE TERNARY COMPLEX OF THE EUBACTERIAL DNA POLYMERASE III ALPHA-SUBUNIT
Descriptor:DNA substrate template strand, DNA substrate primer strand, DNA polymerase III subunit alpha, ...
Authors:Wing, R.A., Bailey, S., Steitz, T.A.
Deposit date:2008-07-31
Release date:2008-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4.6 Å)
Cite:Insights into the Replisome from the Structure of a Ternary Complex of the DNA Polymerase III alpha-Subunit.
J.Mol.Biol., 382, 2008
3F2B
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DNA POLYMERASE POLC FROM GEOBACILLUS KAUSTOPHILUS COMPLEX WITH DNA, DGTP, MG AND ZN
Descriptor:DNA-directed DNA polymerase III alpha chain, 5'-D(*DCP*DAP*DGP*DTP*DGP*DAP*DGP*DAP*DCP*DGP*DGP*DGP*DCP*DAP*DAP*DCP*DC)-3', 5'-D(*DAP*DTP*DAP*DAP*DCP*DGP*DGP*DTP*DTP*DGP*DCP*DCP*DCP*DGP*DTP*DCP*DTP*DCP*DAP*DCP*DTP*DG)-3', ...
Authors:Davies, D.R., Evans, R.J., Bullard, J.M., Christensen, J., Green, L.S., Guiles, J.W., Ribble, W.K., Janjic, N., Jarvis, T.C.
Deposit date:2008-10-29
Release date:2009-01-20
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structure of PolC reveals unique DNA binding and fidelity determinants.
Proc.Natl.Acad.Sci.USA, 105, 2008
3F2C
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DNA POLYMERASE POLC FROM GEOBACILLUS KAUSTOPHILUS COMPLEX WITH DNA, DGTP AND MN
Descriptor:GEOBACILLUS KAUSTOPHILUS DNA POLC, 5'-D(*DCP*DAP*DGP*DTP*DGP*DAP*DGP*DAP*DCP*DGP*DGP*DGP*DCP*DAP*DAP*DCP*DC)-3', 5'-D(*DAP*DTP*DAP*DAP*DCP*DGP*DGP*DTP*DTP*DGP*DCP*DCP*DCP*DGP*DTP*DCP*DTP*DCP*DAP*DCP*DTP*DG)-3', ...
Authors:Davies, D.R., Evans, R.J., Bullard, J.M., Christensen, J., Green, L.S., Guiles, J.W., Ribble, W.K., Janjic, N., Jarvis, T.C.
Deposit date:2008-10-29
Release date:2009-01-20
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of PolC reveals unique DNA binding and fidelity determinants.
Proc.Natl.Acad.Sci.USA, 105, 2008
3F2D
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DNA POLYMERASE POLC FROM GEOBACILLUS KAUSTOPHILUS COMPLEX WITH DNA, DGTP, MN AND ZN
Descriptor:5'-D(*DCP*DAP*DGP*DTP*DGP*DAP*DGP*DAP*DCP*DGP*DGP*DGP*DCP*DAP*DAP*DCP*DC)-3', 5'-D(*DAP*DTP*DAP*DAP*DCP*DGP*DGP*DTP*DTP*DGP*DCP*DCP*DCP*DGP*DTP*DCP*DTP*DCP*DAP*DCP*DTP*DG)-3', GEOBACILLUS KAUSTOPHILUS DNA POLC, ...
Authors:Davies, D.R., Evans, R.J., Bullard, J.M., Christensen, J., Green, L.S., Guiles, J.W., Ribble, W.K., Janjic, N., Jarvis, T.C.
Deposit date:2008-10-29
Release date:2009-01-20
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structure of PolC reveals unique DNA binding and fidelity determinants.
Proc.Natl.Acad.Sci.USA, 105, 2008
4IQJ
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STRUCTURE OF POLIIIALPHA-TAUC-DNA COMPLEX SUGGESTS AN ATOMIC MODEL OF THE REPLISOME
Descriptor:DNA (5'-D(P*CP*GP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*A)-3'), DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*GP*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*CP*G)-3'), DNA (5'-D(P*CP*GP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*(DOC))-3'), ...
Authors:Liu, B., Lin, J., Steitz, T.
Deposit date:2013-01-11
Release date:2013-03-13
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of PolIIIalpha-Tauc-DNA complex suggests an atomic model of the replisome
Structure, 21, 2013
4JOM
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STRUCTURE OF E. COLI POL III 3MPHP MUTANT
Descriptor:DNA polymerase III subunit alpha, PHOSPHATE ION, ZINC ION, ...
Authors:Barros, T., Guenther, J., Kelch, B., Anaya, J., Prabhakar, A., O'Donnell, M., Kuriyan, J., Lamers, M.H.
Deposit date:2013-03-18
Release date:2013-05-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A structural role for the PHP domain in E. coli DNA polymerase III.
Bmc Struct.Biol., 13, 2013
5FKU
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CRYO-EM STRUCTURE OF THE E. COLI REPLICATIVE DNA POLYMERASE COMPLEX IN DNA FREE STATE (DNA POLYMERASE III ALPHA, BETA, EPSILON, TAU COMPLEX)
Descriptor:DNA POLYMERASE III SUBUNIT ALPHA, DNA POLYMERASE III SUBUNIT BETA, DNA POLYMERASE III SUBUNIT EPSILON, ...
Authors:Fernandez-Leiro, R., Conrad, J., Scheres, S.H.W., Lamers, M.H.
Deposit date:2015-10-20
Release date:2015-11-25
Last modified:2017-04-19
Method:ELECTRON MICROSCOPY (8.34 Å)
Cite:cryo-EM structures of the E. coli replicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease and tau.
Elife, 4, 2015
5FKV
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CRYO-EM STRUCTURE OF THE E. COLI REPLICATIVE DNA POLYMERASE COMPLEX BOUND TO DNA (DNA POLYMERASE III ALPHA, BETA, EPSILON, TAU COMPLEX)
Descriptor:DNA POLYMERASE III SUBUNIT ALPHA, DNA POLYMERASE III BETA, DNA POLYMERASE III EPSILON, ...
Authors:Fernandez-Leiro, R., Conrad, J., Scheres, S.H.W., Lamers, M.H.
Deposit date:2015-10-20
Release date:2015-11-25
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (8 Å)
Cite:cryo-EM structures of the E. coli replicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease and tau.
Elife, 4, 2015
5FKW
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CRYO-EM STRUCTURE OF THE E. COLI REPLICATIVE DNA POLYMERASE COMPLEX BOUND TO DNA (DNA POLYMERASE III ALPHA, BETA, EPSILON)
Descriptor:DNA POLYMERASE III ALPHA, DNA POLYMERASE III BETA, DNA POLYMERASE III EPSILON, ...
Authors:Fernandez-Leiro, R., Conrad, J., Scheres, S.H.W., Lamers, M.H.
Deposit date:2015-10-20
Release date:2015-11-25
Last modified:2017-04-19
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:cryo-EM structures of the E. coli replicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease and tau.
Elife, 4, 2015
5LEW
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DNA POLYMERASE
Descriptor:DNA polymerase III subunit alpha, ZINC ION, SULFATE ION, ...
Authors:Banos-Mateos, S., Lang, U.F., Maslen, S.L., Skehel, J.M., Lamers, M.H.
Deposit date:2016-06-30
Release date:2017-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:High-fidelity DNA replication in Mycobacterium tuberculosis relies on a trinuclear zinc center.
Nat Commun, 8, 2017
5M1S
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CRYO-EM STRUCTURE OF THE E. COLI REPLICATIVE DNA POLYMERASE-CLAMP-EXONUCLASE-THETA COMPLEX BOUND TO DNA IN THE EDITING MODE
Descriptor:DNA polymerase III subunit alpha, DNA polymerase III subunit beta, DNA polymerase III subunit epsilon, ...
Authors:Fernandez-Leiro, R., Conrad, J., Scheres, S.H.W., Lamers, M.H.
Deposit date:2016-10-10
Release date:2017-01-18
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Self-correcting mismatches during high-fidelity DNA replication.
Nat. Struct. Mol. Biol., 24, 2017
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