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1ROC
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BU of 1roc by Molmil
Crystal structure of the histone deposition protein Asf1
Descriptor: Anti-silencing protein 1, BROMIDE ION
Authors:Daganzo, S.M, Erzberger, J.P, Lam, W.M, Skordalakes, E, Zhang, R, Franco, A.A, Brill, S.J, Adams, P.D, Berger, J.M, Kaufman, P.D.
Deposit date:2003-12-02
Release date:2003-12-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure and function of the conserved core of histone deposition protein Asf1.
Curr.Biol., 13, 2003
5UCB
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BU of 5ucb by Molmil
Structure of antigen-Fab complex with engineered switch residue region.
Descriptor: Fab Heavy Chain, Fab Light Chain, Histone chaperone ASF1
Authors:Bailey, L.J, Kossiakoff, A.A, Chaperone-Enabled Studies of Epigenetic Regulation Enzymes (CEBS)
Deposit date:2016-12-22
Release date:2017-12-27
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.521 Å)
Cite:Antibody Switch Residue Engineering for Improved Crystallization Chaperones
To Be Published
5UEK
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BU of 5uek by Molmil
Structure of antigen-Fab 12E complex with Histone chaperone ASF1
Descriptor: Fab 12E Heavy Chain, Fab 12E Light Chain, Histone chaperone ASF1
Authors:Bailey, L.J, Kossiakoff, A.A.
Deposit date:2017-01-02
Release date:2018-01-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Antibody Switch Residue Engineering for Improved Crystallization Chaperones
To Be Published
2HUE
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BU of 2hue by Molmil
Structure of the H3-H4 chaperone Asf1 bound to histones H3 and H4
Descriptor: Anti-silencing protein 1, GLYCEROL, Histone H3, ...
Authors:English, C.M, Churchill, M.E.A, Tyler, J.K.
Deposit date:2006-07-26
Release date:2006-11-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for the histone chaperone activity of asf1.
Cell(Cambridge,Mass.), 127, 2006
5UEA
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BU of 5uea by Molmil
Structure of antigen-Fab complex with Histone chaperone ASF1
Descriptor: Fab Heavy Chain, Fab Light Chain, Histone chaperone ASF1
Authors:Bailey, L.J, Kossiakoff, A.A.
Deposit date:2016-12-29
Release date:2018-01-10
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:Antibody Switch Residue Engineering for Improved Crystallization Chaperones
To Be Published
6ZUF
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BU of 6zuf by Molmil
Urea-based Foldamer Inhibitor chimera C2 in complex with ASF1 Histone chaperone
Descriptor: C2 foldamer/peptide hybrid inhibitor of histone chaperone ASF1, GLYCEROL, Histone chaperone ASF1A, ...
Authors:Bakail, M, Mbianda, J, Perrin, E.M, Guerois, R, Legrand, P, Traore, S, Douat, C, Guichard, G, Ochsenbein, F.
Deposit date:2020-07-22
Release date:2021-06-09
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:Optimal anchoring of a foldamer inhibitor of ASF1 histone chaperone through backbone plasticity.
Sci Adv, 7, 2021
2DZE
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BU of 2dze by Molmil
Crystal structure of histone chaperone Asf1 in complex with a C-terminus of histone H3
Descriptor: 10-mer peptide from Histone H3.1/H3.2, Histone chaperone cia1, TRIETHYLENE GLYCOL
Authors:Padmanabhan, B, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-09-28
Release date:2007-10-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of histone chaperone Asf1 in complex with a C-terminus of histone H3
To be Published
2CU9
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BU of 2cu9 by Molmil
Crystal structure of Histone chaperone cia1
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, Histone chaperone cia1
Authors:Padmanabhan, B, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-25
Release date:2006-08-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structures of Fission Yeast Histone Chaperone Asf1 Complexed with the Hip1 B-domain or the Cac2 C Terminus
J.Biol.Chem., 283, 2008
6F0H
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BU of 6f0h by Molmil
Crystal structure ASF1-ip4
Descriptor: CITRIC ACID, GLYCEROL, Histone chaperone ASF1A, ...
Authors:Bakail, M, Richet, N, Le Du, M.H, Andreani, J, Guerois, R, Ochsenbein, F.
Deposit date:2017-11-20
Release date:2019-06-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Design on a Rational Basis of High-Affinity Peptides Inhibiting the Histone Chaperone ASF1.
Cell Chem Biol, 26, 2019
6F0F
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BU of 6f0f by Molmil
Crystal structure ASF1-ip2_s
Descriptor: Histone chaperone ASF1A, ip2_s
Authors:Gaubert, A, Guichard, B, Murciano, B, Le Du, M.H, Ochsenbein, F, Guerois, R, Andreani, J.
Deposit date:2017-11-20
Release date:2019-06-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design on a Rational Basis of High-Affinity Peptides Inhibiting the Histone Chaperone ASF1.
Cell Chem Biol, 26, 2019
6AYZ
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BU of 6ayz by Molmil
Crystal structure of Asf1-Fab 12E complex
Descriptor: Fab Heavy Chain, Fab Light Chain, Histone chaperone ASF1
Authors:Bailey, L.J, Kossiakoff, A.A.
Deposit date:2017-09-08
Release date:2018-01-17
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.096 Å)
Cite:Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination.
J. Mol. Biol., 430, 2018
7LNY
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BU of 7lny by Molmil
Apo structure of the Histone chaperone ASF1A residues 1-155
Descriptor: Histone chaperone ASF1A
Authors:Simon, B, Boggon, T.J, Calderwood, D, Turk, B.E.
Deposit date:2021-02-08
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry.
Nat Commun, 13, 2022
8CJ2
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BU of 8cj2 by Molmil
Urea-based foldamer inhibitor c3u_5 chimera in complex with ASF1 histone chaperone
Descriptor: GLYCEROL, Histone chaperone ASF1A, SULFATE ION, ...
Authors:Perrin, M.E, Li, B, Mbianda, J, Ropars, V, Legrand, P, Douat, C, Ochsenbein, F, Guichard, G.
Deposit date:2023-02-11
Release date:2023-07-05
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (2.127 Å)
Cite:Unexpected binding modes of inhibitors to the histone chaperone ASF1 revealed by a foldamer scanning approach.
Chem.Commun.(Camb.), 59, 2023
2IDC
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BU of 2idc by Molmil
Structure of the Histone H3-Asf1 Chaperone Interaction
Descriptor: ANTI-SILENCING PROTEIN 1 AND HISTONE H3 CHIMERA
Authors:Antczak, A.J, Tsubota, T, Kaufman, P.D, Berger, J.M.
Deposit date:2006-09-14
Release date:2007-01-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the yeast histone H3-ASF1 interaction: implications for chaperone mechanism, species-specific interactions, and epigenetics.
Bmc Struct.Biol., 6, 2006
4ZBJ
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BU of 4zbj by Molmil
UBN1 peptide bound to H3.3/H4/Asf1
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Histone H3, ...
Authors:Marmorstein, R, Ricketts, M.D, Tang, Y.
Deposit date:2015-04-14
Release date:2015-07-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.248 Å)
Cite:Ubinuclein-1 confers histone H3.3-specific-binding by the HIRA histone chaperone complex.
Nat Commun, 6, 2015
6F0G
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BU of 6f0g by Molmil
Crystal structure ASF1-ip3
Descriptor: Histone chaperone ASF1A, SULFATE ION, ip3
Authors:Gaubert, A, Guichard, B, Richet, N, Le Du, M.H, Andreani, J, Guerois, R, Ochsenbein, F.
Deposit date:2017-11-20
Release date:2019-06-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Design on a Rational Basis of High-Affinity Peptides Inhibiting the Histone Chaperone ASF1.
Cell Chem Biol, 26, 2019
5BNX
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BU of 5bnx by Molmil
Crystal structure of Human MCM2 HBD and ASF1b chaperoning a histone H3.3-H4 dimer
Descriptor: DNA replication licensing factor MCM2, GLYCEROL, Histone H3.3, ...
Authors:Huang, H, Patel, D.J.
Deposit date:2015-05-26
Release date:2015-06-17
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.305 Å)
Cite:A unique binding mode enables MCM2 to chaperone histones H3-H4 at replication forks.
Nat.Struct.Mol.Biol., 22, 2015
4EO5
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BU of 4eo5 by Molmil
Yeast Asf1 bound to H3/H4G94P mutant
Descriptor: ACETATE ION, GLYCEROL, Histone H3.2, ...
Authors:Scorgie, J.K, Churchill, M.E.
Deposit date:2012-04-13
Release date:2012-06-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The conformational flexibility of the C-terminus of histone H4 promotes histone octamer and nucleosome stability and yeast viability.
Epigenetics Chromatin, 5, 2012
2Z34
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BU of 2z34 by Molmil
Crystal structure of SpCia1/Asf1 complex with Hip1
Descriptor: Histone chaperone cia1, Protein hir1
Authors:Malay, A.D, Padmanabhan, B, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-05-31
Release date:2008-03-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of fission yeast histone chaperone Asf1 complexed with the Hip1 B-domain or the Cac2 C terminus
J.Biol.Chem., 283, 2008
5EII
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BU of 5eii by Molmil
Structural determination of an protein complex of a Fab with increased solubility
Descriptor: Fab Heavy Chain, Fab Light Chain, Histone chaperone ASF1
Authors:Bailey, L.J, Kossiakoff, A.A, Chaperone-Enabled Studies of Epigenetic Regulation Enzymes (CEBS)
Deposit date:2015-10-29
Release date:2016-11-09
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Structural determination of an protein complex of a Fab with increased solubility
To Be Published
6AZ2
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BU of 6az2 by Molmil
Crystal structure of Asf1-Fab 12E complex
Descriptor: Fab Heavy Chain, Fab Light Chain, Histone chaperone ASF1
Authors:Bailey, L.J, Kossiakoff, A.A.
Deposit date:2017-09-09
Release date:2018-01-10
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.477 Å)
Cite:Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination.
J. Mol. Biol., 430, 2018
6A6Y
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BU of 6a6y by Molmil
Crystal Structure of Asf1 from Plasmodium falciparum
Descriptor: 1,2-ETHANEDIOL, Histone chaperone ASF1, putative, ...
Authors:Srivastava, D.K, Roy, S.
Deposit date:2018-06-29
Release date:2018-07-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.491 Å)
Cite:Structural and Functional characterization of As1 from Plasmodium falciparum
To Be Published
8CJ1
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BU of 8cj1 by Molmil
Urea-based foldamer inhibitor c3u_3 chimera in complex with ASF1 histone chaperone
Descriptor: Histone chaperone ASF1A, c3u_3 chimera inhibitor of histone chaperone ASF1
Authors:Perrin, M.E, Li, B, Mbianda, J, Ropars, V, Legrand, P, Douat, C, Ochsenbein, F, Guichard, G.
Deposit date:2023-02-11
Release date:2023-07-05
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.564 Å)
Cite:Unexpected binding modes of inhibitors to the histone chaperone ASF1 revealed by a foldamer scanning approach.
Chem.Commun.(Camb.), 59, 2023
2Z3F
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BU of 2z3f by Molmil
Crystal structure of spCia1/Asf1 complexed with Cac2 peptide
Descriptor: Histone chaperone cia1, SPAC26H5.03 protein
Authors:Malay, A.D, Padmanabhan, B, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-06-04
Release date:2008-03-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structures of Fission Yeast Histone Chaperone Asf1 Complexed with the Hip1 B-domain or the Cac2 C Terminus
J.Biol.Chem., 283, 2008
2IO5
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BU of 2io5 by Molmil
Crystal structure of the CIA- histone H3-H4 complex
Descriptor: ASF1A protein, Histone H3.1, Histone H4
Authors:Natsume, R, Akai, Y, Horikoshi, M, Senda, T.
Deposit date:2006-10-10
Release date:2007-02-27
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure and function of the histone chaperone CIA/ASF1 complexed with histones H3 and H4.
Nature, 446, 2007

 

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