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7O4J
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BU of 7o4j by Molmil
Yeast RNA polymerase II transcription pre-initiation complex (consensus)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P.
Deposit date:2021-04-06
Release date:2021-06-16
Last modified:2021-08-04
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
7ML0
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BU of 7ml0 by Molmil
RNA polymerase II pre-initiation complex (PIC1)
Descriptor: BJ4_G0050160.mRNA.1.CDS.1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Yang, C, Fujiwara, R, Kim, H.J, Gorbea Colon, J.J, Steimle, S, Garcia, B.A, Murakami, K.
Deposit date:2021-04-27
Release date:2022-02-02
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II.
Mol.Cell, 82, 2022
7ML4
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BU of 7ml4 by Molmil
RNA polymerase II initially transcribing complex (ITC)
Descriptor: BJ4_G0050160.mRNA.1.CDS.1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Yang, C, Fujiwara, R, Kim, H.J, Gorbea Colon, J.J, Steimle, S, Garcia, B.A, Murakami, K.
Deposit date:2021-04-27
Release date:2022-02-02
Last modified:2022-03-09
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II.
Mol.Cell, 82, 2022
7ZS9
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BU of 7zs9 by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome (complex A)
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Wang, H, Cramer, P.
Deposit date:2022-05-06
Release date:2022-11-16
Last modified:2023-03-01
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structures of transcription preinitiation complex engaged with the +1 nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
7O4I
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BU of 7o4i by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with initial transcription bubble
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P.
Deposit date:2021-04-06
Release date:2021-06-16
Last modified:2021-08-04
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
7O75
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BU of 7o75 by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with open promoter DNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P.
Deposit date:2021-04-13
Release date:2021-06-16
Last modified:2021-08-04
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
8EBU
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BU of 8ebu by Molmil
XPC release from Core7-XPA-DNA (Cy5)
Descriptor: DNA repair protein complementing XP-A cells, DNA repair protein complementing XP-C cells, DNA1, ...
Authors:Kim, J, Yang, W.
Deposit date:2022-08-31
Release date:2023-04-19
Last modified:2023-05-17
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Lesion recognition by XPC, TFIIH and XPA in DNA excision repair.
Nature, 617, 2023
7EGB
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BU of 7egb by Molmil
TFIID-based holo PIC on SCP promoter
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-05
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7ML2
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BU of 7ml2 by Molmil
RNA polymerase II pre-initiation complex (PIC3)
Descriptor: BJ4_G0004860.mRNA.1.CDS.1, BJ4_G0050160.mRNA.1.CDS.1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Yang, C, Fujiwara, R, Kim, H.J, Gorbea Colon, J.J, Steimle, S, Garcia, B.A, Murakami, K.
Deposit date:2021-04-27
Release date:2022-02-02
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II.
Mol.Cell, 82, 2022
7O4L
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BU of 7o4l by Molmil
Yeast TFIIH in the expanded state within the pre-initiation complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P.
Deposit date:2021-04-06
Release date:2021-06-16
Last modified:2021-08-04
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
7O73
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BU of 7o73 by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with closed distorted promoter DNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P.
Deposit date:2021-04-12
Release date:2021-06-16
Last modified:2021-08-04
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
7O72
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BU of 7o72 by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with closed promoter DNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P.
Deposit date:2021-04-12
Release date:2021-06-16
Last modified:2021-08-04
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
7AD8
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BU of 7ad8 by Molmil
Core TFIIH-XPA-DNA complex with modelled p62 subunit
Descriptor: DNA (49-MER), DNA repair protein complementing XP-A cells, General transcription and DNA repair factor IIH helicase subunit XPB, ...
Authors:Koelmel, W, Kuper, J, Kisker, C.
Deposit date:2020-09-14
Release date:2021-07-28
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:The TFIIH subunits p44/p62 act as a damage sensor during nucleotide excision repair.
Nucleic Acids Res., 48, 2020
8EBX
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BU of 8ebx by Molmil
XPA repositioning Core7 of TFIIH relative to XPC-DNA lesion (AP)
Descriptor: CALCIUM ION, Centrin-2, DNA, ...
Authors:Kim, J, Yang, W.
Deposit date:2022-08-31
Release date:2023-04-19
Last modified:2023-05-17
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Lesion recognition by XPC, TFIIH and XPA in DNA excision repair.
Nature, 617, 2023
8EBY
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BU of 8eby by Molmil
XPC release from Core7-XPA-DNA (AP)
Descriptor: DNA, DNA repair protein complementing XP-A cells, DNA repair protein complementing XP-C cells, ...
Authors:Kim, J, Yang, W.
Deposit date:2022-08-31
Release date:2023-04-19
Last modified:2023-05-17
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Lesion recognition by XPC, TFIIH and XPA in DNA excision repair.
Nature, 617, 2023
8CEO
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BU of 8ceo by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with core Mediator and the +1 nucleosome
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Wang, H, Cramer, P.
Deposit date:2023-02-02
Release date:2023-03-08
Last modified:2023-04-19
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
7O4K
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BU of 7o4k by Molmil
Yeast TFIIH in the contracted state within the pre-initiation complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P.
Deposit date:2021-04-06
Release date:2021-06-16
Last modified:2021-08-04
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
6NMI
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BU of 6nmi by Molmil
Cryo-EM structure of the human TFIIH core complex
Descriptor: CDK-activating kinase assembly factor MAT1, General transcription and DNA repair factor IIH helicase subunit XPB, General transcription and DNA repair factor IIH helicase subunit XPD, ...
Authors:Greber, B.J, Toso, D, Fang, J, Nogales, E.
Deposit date:2019-01-10
Release date:2019-03-13
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:The complete structure of the human TFIIH core complex.
Elife, 8, 2019
8EBT
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BU of 8ebt by Molmil
XPA repositioning Core7 of TFIIH relative to XPC-DNA lesion (Cy5)
Descriptor: CALCIUM ION, Centrin-2, DNA, ...
Authors:Kim, J, Yang, W.
Deposit date:2022-08-31
Release date:2023-04-19
Last modified:2023-05-17
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Lesion recognition by XPC, TFIIH and XPA in DNA excision repair.
Nature, 617, 2023
7NVX
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BU of 7nvx by Molmil
TFIIH in a post-translocated state (with ADP-BeF3)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CDK-activating kinase assembly factor MAT1, ...
Authors:Aibara, S, Schilbach, S, Cramer, P.
Deposit date:2021-03-16
Release date:2021-05-05
Last modified:2021-06-16
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structures of mammalian RNA polymerase II pre-initiation complexes.
Nature, 594, 2021
7K01
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BU of 7k01 by Molmil
Structure of TFIIH in TFIIH/Rad4-Rad23-Rad33 DNA opening complex
Descriptor: DNA repair helicase RAD25, DNA repair helicase RAD3, General transcription and DNA repair factor IIH subunit SSL1, ...
Authors:van Eeuwen, T, Min, J.H, Murakami, K.
Deposit date:2020-09-02
Release date:2021-07-28
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structure of TFIIH/Rad4-Rad23-Rad33 in damaged DNA opening in nucleotide excision repair.
Nat Commun, 12, 2021
7EGC
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BU of 7egc by Molmil
p53-bound TFIID-based holo PIC on HDM2 promoter
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-12
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
8EBS
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BU of 8ebs by Molmil
Initial DNA-lesion (Cy5) binding by XPC and TFIIH
Descriptor: CALCIUM ION, Centrin-2, DNA, ...
Authors:Kim, J, Yang, W.
Deposit date:2022-08-31
Release date:2023-04-19
Last modified:2023-05-17
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Lesion recognition by XPC, TFIIH and XPA in DNA excision repair.
Nature, 617, 2023
8BVW
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BU of 8bvw by Molmil
RNA polymerase II pre-initiation complex with the distal +1 nucleosome (PIC-Nuc18W)
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P.
Deposit date:2022-12-20
Release date:2023-05-03
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
7ML1
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BU of 7ml1 by Molmil
RNA polymerase II pre-initiation complex (PIC2)
Descriptor: BJ4_G0050160.mRNA.1.CDS.1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Yang, C, Fujiwara, R, Kim, H.J, Gorbea Colon, J.J, Steimle, S, Garcia, B.A, Murakami, K.
Deposit date:2021-04-27
Release date:2022-02-02
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II.
Mol.Cell, 82, 2022

 

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