4HS5
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FRATAXIN FROM PSYCHROMONAS INGRAHAMII AS A MODEL TO STUDY STABILITY MODULATION WITHIN CYAY PROTEIN FAMILY
Descriptor:Protein CyaY
Authors:Roman, E.A., Cousido-siah, A., Mitschler, A., Podjarny, A., Santos, J.
Deposit date:2012-10-29
Release date:2013-03-13
Last modified:2013-07-31
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Frataxin from Psychromonas ingrahamii as a model to study stability modulation within the CyaY protein family
Biochim.Biophys.Acta, 1834, 2013
1EKG
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MATURE HUMAN FRATAXIN
Descriptor:FRATAXIN
Authors:Dhe-Paganon, S., Shigeta, R., Chi, Y.I., Ristow, M., Shoelson, S.E.
Deposit date:2000-03-08
Release date:2000-11-08
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of human frataxin.
J.Biol.Chem., 275, 2000
1EW4
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI CYAY PROTEIN REVEALS A NOVEL FOLD FOR THE FRATAXIN FAMILY
Descriptor:CYAY PROTEIN
Authors:Suh, S.W., Cho, S., Lee, M.G., Yang, J.K., Lee, J.Y., Song, H.K.
Deposit date:2000-04-22
Release date:2000-08-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of Escherichia coli CyaY protein reveals a previously unidentified fold for the evolutionarily conserved frataxin family.
Proc.Natl.Acad.Sci.USA, 97, 2000
1LY7
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THE SOLUTION STRUCTURE OF THE THE C-TERMINAL DOMAIN OF FRATAXIN, THE PROTEIN RESPONSIBLE FOR FRIEDREICH ATAXIA
Descriptor:frataxin
Authors:Musco, G., Stier, G., Kolmerer, B., Adinolfi, S., Martin, S., Frenkiel, T., Gibson, T., Pastore, A.
Deposit date:2002-06-07
Release date:2002-06-26
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Towards a structural understanding of Friedreich's ataxia: the solution structure of frataxin
Structure Fold.Des., 8, 2000
1SOY
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SOLUTION STRUCTURE OF THE BACTERIAL FRATAXIN ORTHOLOGUE, CYAY
Descriptor:CyaY protein
Authors:Nair, M., Adinolfi, S., Pastore, C., Kelly, G., Temussi, P., Pastore, A.
Deposit date:2004-03-16
Release date:2004-11-23
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of the Bacterial Frataxin Ortholog, CyaY; Mapping the Iron Binding Sites
Structure, 12, 2004
2EFF
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CRYSTAL STRUCTURE ANALYSIS OF THE COMPLEX BETWEEN CYAY AND CO(II)
Descriptor:Protein cyaY, COBALT (II) ION
Authors:Sica, F., Franzese, M.
Deposit date:2007-02-22
Release date:2007-10-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Understanding the binding properties of an unusual metal-binding protein - a study of bacterial frataxin
Febs J., 274, 2007
2FQL
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CRYSTAL STRUCTURE OF TRIMERIC FRATAXIN FROM THE YEAST SACCHAROMYCES CEREVISIAE
Descriptor:Frataxin homolog, mitochondrial
Authors:Al-Karadaghi, S., Karlberg, T.
Deposit date:2006-01-18
Release date:2006-11-07
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:The structures of frataxin oligomers reveal the mechanism for the delivery and detoxification of iron.
Structure, 14, 2006
2GA5
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YEAST FRATAXIN
Descriptor:Frataxin homolog, mitochondrial
Authors:He, Y., Alam, S.L., Proteasa, S.V., Zhang, Y., Lesuisse, E., Dancis, A.
Deposit date:2006-03-07
Release date:2006-03-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Yeast Frataxin Solution Structure, Iron Binding and Ferrochelatase Interaction
Biochemistry, 43, 2004
2P1X
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CRYSTAL STRUCTURE ANALYSIS OF THE COMPLEX BETWEEN CYAY AND EU(III)
Descriptor:Protein cyaY, EUROPIUM (III) ION
Authors:Sica, F., Franzese, M.
Deposit date:2007-03-06
Release date:2007-10-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Understanding the binding properties of an unusual metal-binding protein-a study of bacterial frataxin
Febs J., 274, 2007
3OEQ
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CRYSTAL STRUCTURE OF TRIMERIC FRATAXIN FROM THE YEAST SACCHAROMYCES CEREVISIAE, WITH FULL LENGTH N-TERMINUS
Descriptor:Frataxin homolog, mitochondrial
Authors:Soderberg, C.A.G., Rajan, S., Gakh, O., Ta, C., Isaya, G., Al-Karadaghi, S.
Deposit date:2010-08-13
Release date:2011-08-24
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Oligomerization Propensity and Flexibility of Yeast Frataxin Studied by X-ray Crystallography and Small-Angle X-ray Scattering.
J.Mol.Biol., 414, 2011
3OER
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CRYSTAL STRUCTURE OF TRIMERIC FRATAXIN FROM THE YEAST SACCHAROMYCES CEREVISIAE, COMPLEXED WITH COBALT
Descriptor:Frataxin homolog, mitochondrial, COBALT (II) ION
Authors:Soderberg, C.A.G., Rajan, S., Gakh, O., Ta, C., Isaya, G., Al-Karadaghi, S.
Deposit date:2010-08-13
Release date:2011-08-24
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Oligomerization Propensity and Flexibility of Yeast Frataxin Studied by X-ray Crystallography and Small-Angle X-ray Scattering.
J.Mol.Biol., 414, 2011
3S4M
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CRYSTAL STRUCTURE OF WILD-TYPE HUMAN FRATAXIN
Descriptor:Frataxin, mitochondrial
Authors:Tsai, C.-L., Bridwell-Rabb, J., Barondeau, D.P.
Deposit date:2011-05-19
Release date:2011-06-29
Last modified:2011-08-03
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Friedreich's Ataxia Variants I154F and W155R Diminish Frataxin-Based Activation of the Iron-Sulfur Cluster Assembly Complex.
Biochemistry, 50, 2011
3S5D
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CRYSTAL STRUCTURE OF HUMAN FRATAXIN VARIANT W155A
Descriptor:Frataxin, mitochondrial, SULFATE ION
Authors:Tsai, C.-L., Bridwell-Rabb, J., Barondeau, D.P.
Deposit date:2011-05-23
Release date:2011-06-29
Last modified:2011-08-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Friedreich's Ataxia Variants I154F and W155R Diminish Frataxin-Based Activation of the Iron-Sulfur Cluster Assembly Complex.
Biochemistry, 50, 2011
3S5E
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CRYSTAL STRUCTURE OF HUMAN FRATAXIN VARIANT W155R, ONE OF THE FRIEDREICH'S ATAXIA POINT MUTATIONS
Descriptor:Frataxin, mitochondrial, MAGNESIUM ION
Authors:Tsai, C.-L., Bridwell-Rabb, J., Barondeau, D.P.
Deposit date:2011-05-23
Release date:2011-06-29
Last modified:2011-08-03
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Friedreich's Ataxia Variants I154F and W155R Diminish Frataxin-Based Activation of the Iron-Sulfur Cluster Assembly Complex.
Biochemistry, 50, 2011
3S5F
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CRYSTAL STRUCTURE OF HUMAN FRATAXIN VARIANT W155F
Descriptor:Frataxin, mitochondrial, MAGNESIUM ION
Authors:Tsai, C.-L., Bridwell-Rabb, J., Barondeau, D.P.
Deposit date:2011-05-23
Release date:2011-06-29
Last modified:2011-08-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Friedreich's Ataxia Variants I154F and W155R Diminish Frataxin-Based Activation of the Iron-Sulfur Cluster Assembly Complex.
Biochemistry, 50, 2011
3T3J
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1.70 A STRUCTURE OF FRIEDREICH'S ATAXIA FRATAXIN VARIANT N146K
Descriptor:Frataxin, mitochondrial
Authors:Bridwell-Rabb, J., Winn, A.M., Barondeau, D.P.
Deposit date:2011-07-25
Release date:2011-08-10
Last modified:2011-08-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure-Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe-S Assembly Complex.
Biochemistry, 50, 2011
3T3K
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1.24 A STRUCTURE OF FRIEDREICH'S ATAXIA FRATAXIN VARIANT Q148R
Descriptor:Frataxin, mitochondrial
Authors:Bridwell-Rabb, J., Winn, A.M., Barondeau, D.P.
Deposit date:2011-07-25
Release date:2011-08-10
Last modified:2011-08-31
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Structure-Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe-S Assembly Complex.
Biochemistry, 50, 2011
3T3L
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1.15 A STRUCTURE OF HUMAN FRATAXIN VARIANT Q153A
Descriptor:Frataxin, mitochondrial, SULFATE ION
Authors:Bridwell-Rabb, J., Winn, A.M., Barondeau, D.P.
Deposit date:2011-07-25
Release date:2011-08-10
Last modified:2011-08-31
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Structure-Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe-S Assembly Complex.
Biochemistry, 50, 2011
3T3T
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1.38 A STRUCTURE OF HUMAN FRATAXIN VARIANT Q148G
Descriptor:Frataxin, mitochondrial, SULFATE ION
Authors:Bridwell-Rabb, J., Winn, A.M., Barondeau, D.P.
Deposit date:2011-07-25
Release date:2011-08-10
Last modified:2011-08-31
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Structure-Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe-S Assembly Complex.
Biochemistry, 50, 2011
3T3X
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1.57 A STRUCTURE OF FRIEDREICH'S ATAXIA FRATAXIN VARIANT R165C
Descriptor:Frataxin, mitochondrial, SULFATE ION
Authors:Bridwell-Rabb, J., Winn, A.M., Barondeau, D.P.
Deposit date:2011-07-25
Release date:2011-08-10
Last modified:2011-08-31
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Structure-Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe-S Assembly Complex.
Biochemistry, 50, 2011
4EC2
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CRYSTAL STRUCTURE OF TRIMERIC FRATAXIN FROM THE YEAST SACCHAROMYCES CEREVISIAE, COMPLEXED WITH FERROUS
Descriptor:Frataxin homolog, mitochondrial, FE (II) ION
Authors:Soderberg, C.A.G., Rajan, S., Gakh, O., Isaya, G., Al-Karadaghi, S.
Deposit date:2012-03-26
Release date:2013-01-30
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (3.002 Å)
Cite:The molecular basis of iron-induced oligomerization of frataxin and the role of the ferroxidation reaction in oligomerization.
J.Biol.Chem., 288, 2013
4JPD
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THE STRUCTURE OF CYAY FROM BURKHOLDERIA CENOCEPACIA
Descriptor:Protein CyaY, ACETATE ION, SODIUM ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2013-03-19
Release date:2013-03-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structure of CyaY from Burkholderia cenocepacia
To be Published
4LK8
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CRYSTAL STRUCTURE OF CYAY PROTEIN FROM PSYCHROMONAS INGRAHAMII IN COMPLEX WITH CO(II)
Descriptor:Protein CyaY, COBALT (II) ION
Authors:Noguera, M.E., Roman, E.A., Cousido-Siah, A., Mitschler, A., Podjarny, A., Santos, J.
Deposit date:2013-07-07
Release date:2014-07-16
Last modified:2016-09-21
Method:X-RAY DIFFRACTION (1.494 Å)
Cite:Structural characterization of metal binding to a cold-adapted frataxin
J.Biol.Inorg.Chem., 20, 2015
4LP1
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CRYSTAL STRUCTURE OF CYAY PROTEIN FROM PSYCHROMONAS INGRAHAMII IN COMPLEX WITH EU(III)
Descriptor:Protein CyaY, EUROPIUM (III) ION
Authors:Noguera, M.E., Roman, E.A., Cousido-Siah, A., Mitschler, A., Podjarny, A., Santos, J.
Deposit date:2013-07-14
Release date:2014-07-16
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.803 Å)
Cite:Structural characterization of metal binding to a cold-adapted frataxin
J.Biol.Inorg.Chem., 20, 2015
5KZ5
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ARCHITECTURE OF THE HUMAN MITOCHONDRIAL IRON-SULFUR CLUSTER ASSEMBLY MACHINERY: THE COMPLEX FORMED BY THE IRON DONOR, THE SULFUR DONOR, AND THE SCAFFOLD
Descriptor:Cysteine desulfurase, mitochondrial, Frataxin, ...
Authors:Gakh, O., Ranatunga, W., Smith, D.Y., Ahlgren, E.C., Al-Karadaghi, S., Thompson, J.R., Isaya, G.
Deposit date:2016-07-22
Release date:2016-08-31
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (14.3 Å)
Cite:Architecture of the Human Mitochondrial Iron-Sulfur Cluster Assembly Machinery.
J.Biol.Chem., 291, 2016
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