8UUK
| Pendrin in apo | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CHOLESTEROL, Lauryl Maltose Neopentyl Glycol, ... | Authors: | Wang, L, Hoang, A, Zhou, M. | Deposit date: | 2023-11-01 | Release date: | 2024-02-07 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Mechanism of anion exchange and small-molecule inhibition of pendrin. Nat Commun, 15, 2024
|
|
8UC1
| |
8SIE
| Pendrin in complex with bicarbonate | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, BICARBONATE ION, CHOLESTEROL, ... | Authors: | Wang, L, Hoang, A, Zhou, M. | Deposit date: | 2023-04-16 | Release date: | 2024-02-07 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Mechanism of anion exchange and small-molecule inhibition of pendrin. Nat Commun, 15, 2024
|
|
8SHC
| Pendrin in complex with Niflumic acid | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}NICOTINIC ACID, CHLORIDE ION, ... | Authors: | Wang, L, Hoang, A, Zhou, M. | Deposit date: | 2023-04-13 | Release date: | 2024-02-07 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Mechanism of anion exchange and small-molecule inhibition of pendrin. Nat Commun, 15, 2024
|
|
8SH3
| Pendrin in complex with iodide | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CHOLESTEROL, IODIDE ION, ... | Authors: | Wang, L, Hoang, A, Zhou, M. | Deposit date: | 2023-04-13 | Release date: | 2024-02-07 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Mechanism of anion exchange and small-molecule inhibition of pendrin. Nat Commun, 15, 2024
|
|
8SGW
| Pendrin in complex with chloride | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CHLORIDE ION, CHOLESTEROL, ... | Authors: | Wang, L, Hoang, A, Zhou, M. | Deposit date: | 2023-04-13 | Release date: | 2024-02-07 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Mechanism of anion exchange and small-molecule inhibition of pendrin. Nat Commun, 15, 2024
|
|
8OPQ
| Structure of Human Solute Carrier 26 family member A6 (SLC26A6) anion transporter in an inward-facing state | Descriptor: | CHLORIDE ION, Solute carrier family 26 member 6 | Authors: | Tippett, D.N, Breen, C, Butler, S.J, Sawicka, M, Dutzler, R. | Deposit date: | 2023-04-07 | Release date: | 2023-05-17 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | Structural and functional properties of the transporter SLC26A6 reveal mechanism of coupled anion exchange. Elife, 12, 2023
|
|
8IET
| |
8HZN
| |
7XUJ
| |
7XUL
| Human SLC26A3 in complex with Tenidap | Descriptor: | 5-chloranyl-2-oxidanyl-3-thiophen-2-ylcarbonyl-indole-1-carboxamide, CHOLESTEROL HEMISUCCINATE, Chloride anion exchanger | Authors: | Li, X.R, Chi, X.M, Zhang, Y.Y, Zhou, Q. | Deposit date: | 2022-05-18 | Release date: | 2023-05-24 | Method: | ELECTRON MICROSCOPY (3.16 Å) | Cite: | Structure of human SLC26A3 in complex with Tenidap To Be Published
|
|
7XUH
| Down-regulated in adenoma in complex with TQR1122 | Descriptor: | 2-[4,8-dimethyl-2-oxidanylidene-7-[[3-(trifluoromethyl)phenyl]methoxy]chromen-3-yl]ethanoic acid, CHOLESTEROL HEMISUCCINATE, Chloride anion exchanger | Authors: | Li, X.R, Chi, X.M, Zhang, Y.Y, Zhou, Q. | Deposit date: | 2022-05-18 | Release date: | 2023-08-02 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | structure of human SLC26A3 in complex with TQR1122 To Be Published
|
|
7XLM
| |
7WLE
| |
7WL7
| |
7WL9
| Mouse Pendrin in chloride and bicarbonate in asymmetric state | Descriptor: | CHLORIDE ION, Pendrin | Authors: | Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G. | Deposit date: | 2022-01-12 | Release date: | 2023-04-12 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (3.78 Å) | Cite: | Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger. Nat Commun, 14, 2023
|
|
7WLA
| |
7WL2
| |
7WLB
| |
7WL8
| |
7WK1
| Mouse Pendrin bound chloride in inward state | Descriptor: | CHLORIDE ION, Pendrin | Authors: | Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G. | Deposit date: | 2022-01-08 | Release date: | 2023-04-12 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger. Nat Commun, 14, 2023
|
|
7WK7
| Mouse Pendrin bound bicarbonate in inward state | Descriptor: | BICARBONATE ION, Pendrin | Authors: | Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G. | Deposit date: | 2022-01-08 | Release date: | 2023-05-17 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (3.49 Å) | Cite: | Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger. Nat Commun, 14, 2023
|
|
7SUN
| |
7S9B
| Cryo-EM Structure of dolphin Prestin: Sensor Down I (Expanded) state | Descriptor: | Prestin | Authors: | Bavi, N, Clark, M.D, Contreras, G.F, Shen, R, Reddy, B.G, Milewski, W, Perozo, E. | Deposit date: | 2021-09-20 | Release date: | 2021-11-03 | Last modified: | 2021-12-29 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | The conformational cycle of prestin underlies outer-hair cell electromotility. Nature, 600, 2021
|
|
7S9C
| Cryo-EM Structure of dolphin Prestin: Sensor Down II (Expanded II) state | Descriptor: | Prestin | Authors: | Bavi, N, Clark, M.D, Contreras, G.F, Shen, R, Reddy, B.G, Milewski, W, Perozo, E. | Deposit date: | 2021-09-20 | Release date: | 2021-11-03 | Last modified: | 2021-12-29 | Method: | ELECTRON MICROSCOPY (6.7 Å) | Cite: | The conformational cycle of prestin underlies outer-hair cell electromotility. Nature, 600, 2021
|
|