1AM4
| COMPLEX BETWEEN CDC42HS.GMPPNP AND P50 RHOGAP (H. SAPIENS) | Descriptor: | CDC42HS, MAGNESIUM ION, P50-RHOGAP, ... | Authors: | Rittinger, K, Walker, P, Gamblin, S.J, Smerdon, S.J. | Deposit date: | 1997-06-22 | Release date: | 1998-07-15 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP. Nature, 388, 1997
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1F7C
| CRYSTAL STRUCTURE OF THE BH DOMAIN FROM GRAF, THE GTPASE REGULATOR ASSOCIATED WITH FOCAL ADHESION KINASE | Descriptor: | RHOGAP PROTEIN | Authors: | Longenecker, K.L, Derewenda, U, Sheffield, P.J, Zheng, Y, Derewenda, Z.S. | Deposit date: | 2000-06-26 | Release date: | 2000-12-20 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of the BH domain from graf and its implications for Rho GTPase recognition. J.Biol.Chem., 275, 2000
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1GRN
| CRYSTAL STRUCTURE OF THE CDC42/CDC42GAP/ALF3 COMPLEX. | Descriptor: | ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Nassar, N, Hoffman, G.R, Clardy, J.C, Cerione, R.A. | Deposit date: | 1998-07-30 | Release date: | 1999-12-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP. Nat.Struct.Biol., 5, 1998
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1OW3
| Crystal Structure of RhoA.GDP.MgF3-in Complex with RhoGAP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rho-GTPase-activating protein 1, ... | Authors: | Graham, D.L, Lowe, P.N, Grime, G.W, Marsh, M, Rittinger, K, Smerdon, S.J, Gamblin, S.J, Eccleston, J.F. | Deposit date: | 2003-03-28 | Release date: | 2003-05-06 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | MgF(3)(-) as a Transition State Analog of Phosphoryl Transfer Chem.Biol., 9, 2002
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1PBW
| STRUCTURE OF BCR-HOMOLOGY (BH) DOMAIN | Descriptor: | PHOSPHATIDYLINOSITOL 3-KINASE | Authors: | Musacchio, A, Cantley, L.C, Harrison, S.C. | Deposit date: | 1996-10-17 | Release date: | 1997-03-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of the breakpoint cluster region-homology domain from phosphoinositide 3-kinase p85 alpha subunit. Proc.Natl.Acad.Sci.USA, 93, 1996
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1RGP
| GTPASE-ACTIVATION DOMAIN FROM RHOGAP | Descriptor: | RHOGAP | Authors: | Barrett, T, Xiao, B, Dodson, E.J, Dodson, G, Ludbrook, S.B, Nurmahomed, K, Gamblin, S.J, Musacchio, A, Smerdon, S.J, Eccleston, J.F. | Deposit date: | 1996-12-05 | Release date: | 1997-10-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The structure of the GTPase-activating domain from p50rhoGAP. Nature, 385, 1997
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1TX4
| RHO/RHOGAP/GDP(DOT)ALF4 COMPLEX | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, P50-RHOGAP, ... | Authors: | Rittinger, K, Walker, P.A, Smerdon, S.J, Gamblin, S.J. | Deposit date: | 1997-07-29 | Release date: | 1998-09-16 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue. Nature, 389, 1997
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1XA6
| Crystal Structure of the Human Beta2-Chimaerin | Descriptor: | Beta2-chimaerin, ZINC ION | Authors: | Canagarajah, B, Leskow, F.C, Ho, J.Y, Mischak, H, Saidi, L.F, Kazanietz, M.G, Hurley, J.H. | Deposit date: | 2004-08-25 | Release date: | 2004-11-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural mechanism for lipid activation of the Rac-specific GAP, beta2-chimaerin. Cell(Cambridge,Mass.), 119, 2004
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2EE4
| Solution structure of the RhoGAP domain from human Rho GTPase activating protein 5 variant | Descriptor: | Rho GTPase activating protein 5 variant | Authors: | Tomizawa, T, Tochio, N, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-02-15 | Release date: | 2007-08-21 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the RhoGAP domain from human Rho GTPase activating protein 5 variant To be Published
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2EE5
| Solution structure of the N-teruminus extended RhoGAP domain from human Rho GTPase activating protein 5 variant | Descriptor: | Rho GTPase activating protein 5 variant | Authors: | Tomizawa, T, Tochio, N, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-02-15 | Release date: | 2007-08-21 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the N-teruminus extended RhoGAP domain from human Rho GTPase activating protein 5 variant To be Published
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2MBG
| Rlip76 (gap-gbd) | Descriptor: | RalA-binding protein 1 | Authors: | Rajasekar, K.V, Campbell, L.J, Nietlispach, D, Owen, D, Mott, H.R. | Deposit date: | 2013-07-30 | Release date: | 2013-12-04 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The Structure of the RLIP76 RhoGAP-Ral Binding Domain Dyad: Fixed Position of the Domains Leads to Dual Engagement of Small G Proteins at the Membrane. Structure, 21, 2013
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2NGR
| TRANSITION STATE COMPLEX FOR GTP HYDROLYSIS BY CDC42: COMPARISONS OF THE HIGH RESOLUTION STRUCTURES FOR CDC42 BOUND TO THE ACTIVE AND CATALYTICALLY COMPROMISED FORMS OF THE CDC42-GAP. | Descriptor: | ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Nassar, N, Hoffman, G, Clardy, J, Cerione, R. | Deposit date: | 1998-07-31 | Release date: | 1999-01-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP. Nat.Struct.Biol., 5, 1998
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2OSA
| The Rho-GAP domain of human N-chimaerin | Descriptor: | N-chimaerin | Authors: | Walker, J.R, Hong, B.S, Shen, L, Arrowsmith, C.H, Sundstrom, M, Weigelt, J, Edwards, A.M, Bochkarev, A, Park, H.W, Structural Genomics Consortium (SGC) | Deposit date: | 2007-02-05 | Release date: | 2007-03-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the Rho-GAP domain from human N-chimaerin To be Published
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2OVJ
| The crystal structure of the human Rac GTPase activating protein 1 (RACGAP1) MgcRacGAP. | Descriptor: | 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, Rac GTPase-activating protein 1 | Authors: | Shrestha, L, Papagrigoriou, E, Soundararajan, M, Elkins, J, Johansson, C, von Delft, F, Pike, A.C.W, Burgess, N, Turnbull, A, Debreczeni, J, Gorrec, F, Umeano, C, Edwards, A, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC) | Deposit date: | 2007-02-14 | Release date: | 2007-02-27 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | The crystal structure of the human Rac GTPase activating protein 1 (RACGAP1) MgcRacGAP. To be Published
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2QV2
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2XS6
| CRYSTAL STRUCTURE OF THE RHOGAP DOMAIN OF HUMAN PIK3R2 | Descriptor: | CHLORIDE ION, PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT BETA | Authors: | Tresaugues, L, Welin, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kol, S, Kotenyova, T, Kouznetsova, E, Moche, M, Nyman, T, Persson, C, Schuler, H, Schutz, P, Siponen, M.I, Thorsell, A.G, van der Berg, S, Wahlberg, E, Weigelt, J, Nordlund, P. | Deposit date: | 2010-09-24 | Release date: | 2010-11-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | The Structure and Catalytic Mechanism of Human Sphingomyelin Phosphodiesterase Like 3A - an Acid Sphingomyelinase Homolog with a Novel Nucleotide Hydrolase Activity. FEBS J., 283, 2016
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3BYI
| Crystal structure of human Rho GTPase activating protein 15 (ARHGAP15) | Descriptor: | Rho GTPase activating protein 15 | Authors: | Shrestha, L, Tickle, J, Elkins, J, Burgess-Brown, N, Johansson, C, Papagrigoriou, E, Kavanagh, K, Pike, A.C.W, Ugochukwu, E, Uppenberg, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Doyle, D, Structural Genomics Consortium (SGC) | Deposit date: | 2008-01-16 | Release date: | 2008-02-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystal Structure of Human Rho GTPase Activating Protein 15 (ARHGAP15). To be Published
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3CXL
| Crystal structure of human chimerin 1 (CHN1) | Descriptor: | N-chimerin, UNKNOWN ATOM OR ION, ZINC ION | Authors: | Shen, L, Buck, M, Tong, Y, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Wilkstrom, M, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2008-04-24 | Release date: | 2008-08-05 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of human chimerin 1 (CHN1). To be Published
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3EAP
| Crystal structure of the RhoGAP domain of ARHGAP11A | Descriptor: | Rho GTPase-activating protein 11A, UNKNOWN ATOM OR ION | Authors: | Shen, Y, Shen, L, Tong, Y, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium, Structural Genomics Consortium (SGC) | Deposit date: | 2008-08-26 | Release date: | 2008-09-02 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the RhoGAP domain of ARHGAP11A To be Published
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3FK2
| Crystal structure of the RhoGAP domain of human glucocorticoid receptor DNA-binding factor 1 | Descriptor: | Glucocorticoid receptor DNA-binding factor 1, UNKNOWN ATOM OR ION | Authors: | Nedyalkova, L, Tong, Y, Tempel, W, Loppnau, P, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2008-12-15 | Release date: | 2008-12-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of the RhoGAP domain of human glucocorticoid receptor DNA-binding factor 1 To be Published
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3IUG
| Crystal structure of the RhoGAP domain of RICS | Descriptor: | Rho/Cdc42/Rac GTPase-activating protein RICS, UNKNOWN ATOM OR ION | Authors: | Nedyalkova, L, Tempel, W, Tong, Y, Li, Y, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2009-08-31 | Release date: | 2009-09-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Crystal structure of the RhoGAP domain of RICS to be published
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3KUQ
| Crystal structure of the DLC1 RhoGAP domain | Descriptor: | Rho GTPase-activating protein 7, UNKNOWN ATOM OR ION | Authors: | Nedyalkova, L, Tempel, W, Tong, Y, MacKenzie, F, Shen, L, Zhong, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2009-11-27 | Release date: | 2010-01-26 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the DLC1 RhoGAP domain to be published
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3MSX
| Crystal structure of RhoA.GDP.MgF3 in complex with GAP domain of ArhGAP20 | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rho GTPase-activating protein 20, ... | Authors: | Utepbergenov, D, Cooper, D.R, Derewenda, U, Derewenda, Z.S. | Deposit date: | 2010-04-29 | Release date: | 2011-03-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Mechanism of molecular specificity of RhoGAP domains towards small GTPases of RhoA family. To be Published
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3QIS
| Recognition of the F&H motif by the Lowe Syndrome protein OCRL | Descriptor: | Inositol polyphosphate 5-phosphatase OCRL-1, Protein FAM109A | Authors: | Pirruccello, M, Swan, L.E, Folta-Stogniew, E, De Camilli, P. | Deposit date: | 2011-01-27 | Release date: | 2011-06-15 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Recognition of the F&H motif by the Lowe syndrome protein OCRL. Nat.Struct.Mol.Biol., 18, 2011
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3W6R
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