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1GCN
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BU of 1gcn by Molmil
X-RAY ANALYSIS OF GLUCAGON AND ITS RELATIONSHIP TO RECEPTOR BINDING
Descriptor: GLUCAGON
Authors:Blundell, T.L, Sasaki, K, Dockerill, S, Tickle, I.J.
Deposit date:1977-10-17
Release date:1977-11-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:X-ray analysis of glucagon and its relationship to receptor binding.
Nature, 257, 1975
1BH0
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STRUCTURE OF A GLUCAGON ANALOG
Descriptor: GLUCAGON
Authors:Sturm, N.S, Lin, Y, Burley, S.K, Krstenansky, J.L, Ahn, J.-M, Azizeh, B.Y, Trivedi, D, Hruby, V.J.
Deposit date:1998-06-11
Release date:1998-11-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure-function studies on positions 17, 18, and 21 replacement analogues of glucagon: the importance of charged residues and salt bridges in glucagon biological activity.
J.Med.Chem., 41, 1998
1D0R
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SOLUTION STRUCTURE OF GLUCAGON-LIKE PEPTIDE-1-(7-36)-AMIDE IN TRIFLUOROETHANOL/WATER
Descriptor: GLUCAGON-LIKE PEPTIDE-1-(7-36)-AMIDE
Authors:Chang, X, Keller, D, Bjorn, S, Led, J.J.
Deposit date:1999-09-14
Release date:2002-10-16
Last modified:2024-04-10
Method:SOLUTION NMR
Cite:Structure and Folding of Glucagon-like Peptide-1-(7-36)-amide in Trifluoroethanol Studied by NMR
MAGN.RESON.CHEM., 39, 2001
1GEA
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BU of 1gea by Molmil
RECEPTOR-BOUND CONFORMATION OF PACAP21
Descriptor: PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE
Authors:Inooka, H, Ohtaki, T, Kitahara, O, Ikegami, T, Endo, S, Kitada, C, Ogi, K, Onda, H, Fujino, M, Shirakawa, M.
Deposit date:2000-10-20
Release date:2001-04-20
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Conformation of a peptide ligand bound to its G-protein coupled receptor.
Nat.Struct.Biol., 8, 2001
1JRJ
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BU of 1jrj by Molmil
Solution structure of exendin-4 in 30-vol% trifluoroethanol
Descriptor: Exendin-4
Authors:Neidigh, J.W, Fesinmeyer, R.M, Prickett, K.S, Andersen, N.H.
Deposit date:2001-08-13
Release date:2001-11-21
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Exendin-4 and glucagon-like-peptide-1: NMR structural comparisons in the solution and micelle-associated states.
Biochemistry, 40, 2001
1KX6
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BU of 1kx6 by Molmil
NMR solution structure of Glucagon in a lipid-water interphase
Descriptor: Glucagon
Authors:Braun, W, Wider, G, Lee, K.H, Wuthrich, K.
Deposit date:2002-01-31
Release date:2002-02-13
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Conformation of glucagon in a lipid-water interphase by 1H nuclear magnetic resonance.
J.Mol.Biol., 169, 1983
1NAU
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NMR Solution Structure of the Glucagon Antagonist [desHis1, desPhe6, Glu9]Glucagon Amide in the Presence of Perdeuterated Dodecylphosphocholine Micelles
Descriptor: Glucagon
Authors:Ying, J, Ahn, J.-M, Jacobsen, N.E, Brown, M.F, Hruby, V.J.
Deposit date:2002-11-28
Release date:2003-03-18
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:NMR Solution Structure of the Glucagon Antagonist [desHis1, desPhe6, Glu9]Glucagon Amide in the Presence of Perdeuterated Dodecylphosphocholine Micelles
Biochemistry, 42, 2003
1T5Q
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Solution Structure of GIP(1-30)amide in TFE/Water
Descriptor: Gastric inhibitory polypeptide
Authors:Alana, I, Hewage, C.M, Malthouse, J.P.G, Parker, J.C, Gault, V.A, O'Harte, F.P.M.
Deposit date:2004-05-05
Release date:2004-11-16
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:NMR structure of the glucose-dependent insulinotropic polypeptide fragment, GIP(1-30)amide.
Biochem.Biophys.Res.Commun., 325, 2004
2D2P
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The solution structure of micelle-bound peptide
Descriptor: Pituitary adenylate cyclase activating polypeptide-38
Authors:Tateishi, Y, Jee, J.G, Inooka, H, Tochio, H, Hiroaki, H, Shirakawa, M.
Deposit date:2005-09-14
Release date:2006-09-26
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:The solution structure of micelle-bound peptide
To be Published
2B4N
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Solution Structure of Glucose-Dependent Insulinotropic Polypeptide
Descriptor: Gastric inhibitory polypeptide
Authors:Alana, I, Hewage, C.M, O'Harte, F.P.M, Malthouse, J.P.G.
Deposit date:2005-09-26
Release date:2006-05-02
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:NMR and alanine scan studies of glucose-dependent insulinotropic polypeptide in water.
J.Biol.Chem., 281, 2006
2G49
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Crystal structure of human insulin-degrading enzyme in complex with glucagon
Descriptor: 1,4-DIETHYLENE DIOXIDE, Insulin-degrading enzyme, glucagon preproprotein
Authors:Shen, Y, Tang, W.-J.
Deposit date:2006-02-21
Release date:2006-10-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism.
Nature, 443, 2006
2OBU
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Solution structure of GIP in TFE/water
Descriptor: Gastric inhibitory polypeptide
Authors:Alana, I, Malthouse, J.P.G, O'Harte, F.P.M, Hewage, C.M.
Deposit date:2006-12-20
Release date:2007-06-05
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:The bioactive conformation of glucose-dependent insulinotropic polypeptide by NMR and CD spectroscopy
Proteins, 68, 2007
2JOD
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BU of 2jod by Molmil
Pac1-Rshort N-terminal EC domain Pacap(6-38) complex
Descriptor: Pituitary adenylate cyclase-activating polypeptide, Pituitary adenylate cyclase-activating polypeptide type I receptor
Authors:Olejniczak, E.T, Sun, C, Song, D, Davis-Taber, R.A, Barrett, L.W, Scott, V.E, Richardson, P.L, Pereda-lopez, A, Uchic, M.E, Solomon, L.R, Lake, M.R, Walter, K.A, Hajduk, P.J.
Deposit date:2007-03-07
Release date:2007-05-22
Last modified:2023-12-20
Method:SOLUTION NMR
Cite:Solution structure and mutational analysis of pituitary adenylate cyclase-activating polypeptide binding to the extracellular domain of PAC1-RS.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2QKH
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Crystal structure of the extracellular domain of human GIP receptor in complex with the hormone GIP
Descriptor: Cyclic 2,3-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-2,6-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-3-O-methyl-alpha-D-glucopyranose, D(-)-TARTARIC ACID, Glucose-dependent insulinotropic polypeptide, ...
Authors:Parthier, C, Kleinschmidt, M, Neumann, P, Rudolph, R, Manhart, S, Schlenzig, D, Fanghanel, J, Rahfeld, J.-U, Demuth, H.-U, Stubbs, M.T.
Deposit date:2007-07-11
Release date:2007-08-14
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the incretin-bound extracellular domain of a G protein-coupled receptor
Proc.Natl.Acad.Sci.Usa, 104, 2007
3C59
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Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain
Descriptor: Exendin-4, Glucagon-like peptide 1 receptor, decyl 4-O-alpha-D-glucopyranosyl-1-thio-beta-D-glucopyranoside
Authors:Runge, S.
Deposit date:2008-01-31
Release date:2008-02-19
Last modified:2018-05-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of the Ligand-bound Glucagon-like Peptide-1 Receptor Extracellular Domain
J.Biol.Chem., 283, 2008
3C5T
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BU of 3c5t by Molmil
Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain
Descriptor: Exendin-4, Glucagon-like peptide 1 receptor, decyl 4-O-alpha-D-glucopyranosyl-1-thio-beta-D-glucopyranoside
Authors:Runge, S.
Deposit date:2008-02-01
Release date:2008-02-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of the Ligand-bound Glucagon-like Peptide-1 Receptor Extracellular Domain
J.Biol.Chem., 283, 2008
3IOL
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BU of 3iol by Molmil
Crystal structure of Glucagon-Like Peptide-1 in complex with the extracellular domain of the Glucagon-Like Peptide-1 Receptor
Descriptor: Glucagon, Glucagon-like peptide 1 receptor, decyl 4-O-alpha-D-glucopyranosyl-1-thio-beta-D-glucopyranoside
Authors:Reedtz-Runge, S.
Deposit date:2009-08-14
Release date:2009-10-27
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of glucagon-like peptide-1 in complex with the extracellular domain of the glucagon-like peptide-1 receptor
J.Biol.Chem., 285, 2010
2RRH
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BU of 2rrh by Molmil
NMR structure of vasoactive intestinal peptide in Methanol
Descriptor: VIP peptides
Authors:Umetsu, Y, Tenno, T, Goda, N, Ikegami, T, Hiroaki, H.
Deposit date:2010-11-12
Release date:2011-04-06
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural difference of vasoactive intestinal peptide in two distinct membrane-mimicking environments.
Biochim.Biophys.Acta, 1814, 2011
2L64
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BU of 2l64 by Molmil
NMR Solution structure of GLP-2 in DHPC micelles
Descriptor: Glucagon-like peptide 2
Authors:Venneti, K.C, Hewage, C.M.
Deposit date:2010-11-12
Release date:2011-02-23
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Conformational and molecular interaction studies of glucagon-like peptide-2 with its N-terminal extracellular receptor domain.
Febs Lett., 585, 2011
2L63
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BU of 2l63 by Molmil
NMR solution structure of GLP-2 in 2,2,2 trifluroethanol
Descriptor: Glucagon-like peptide 2
Authors:Venneti, K.C, Hewage, C.M.
Deposit date:2010-11-12
Release date:2011-02-23
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Conformational and molecular interaction studies of glucagon-like peptide-2 with its N-terminal extracellular receptor domain.
Febs Lett., 585, 2011
2L71
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BU of 2l71 by Molmil
NMR solution structure of GIP in Bicellular media
Descriptor: Gastric inhibitory polypeptide
Authors:Venneti, K.C, Alana, I, O'Harte, F.P.M, Malthouse, P.J.G, Hewage, C.M.
Deposit date:2010-12-01
Release date:2011-10-19
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Conformational, receptor interaction and alanine scan studies of glucose-dependent insulinotropic polypeptide
Biochim.Biophys.Acta, 1814, 2011
2L70
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NMR solution structure of GIP in micellular media
Descriptor: Gastric inhibitory polypeptide
Authors:Venneti, K.C, Alana, I, O'Harte, F.P.M, Malthouse, P.J.G, Hewage, C.M.
Deposit date:2010-12-01
Release date:2011-10-19
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Conformational, receptor interaction and alanine scan studies of glucose-dependent insulinotropic polypeptide
Biochim.Biophys.Acta, 1814, 2011
2RRI
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BU of 2rri by Molmil
NMR structure of vasoactive intestinal peptide in DPC Micelle
Descriptor: Vasoactive intestinal peptide
Authors:Umetsu, Y, Tenno, T, Goda, N, Shirakawa, M, Ikegami, T, Hiroaki, H.
Deposit date:2010-12-21
Release date:2011-04-06
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural difference of vasoactive intestinal peptide in two distinct membrane-mimicking environments
Biochim.Biophys.Acta, 1814, 2011
4APD
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BU of 4apd by Molmil
Liraglutide
Descriptor: LIRAGLUTIDE, N-hexadecanoyl-L-glutamic acid
Authors:Ludvigsen, S, Steensgaard, D.B, Thomsen, J.K, Strauss, H, Normann, M.
Deposit date:2012-04-02
Release date:2013-07-10
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Liraglutide
To be Published
2M5P
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Solution structure of lipidated glucagon analog in water
Descriptor: GAMMA-L-GLUTAMIC ACID, Glucagon, PALMITIC ACID
Authors:Ward, B.P, Ma, D.
Deposit date:2013-03-03
Release date:2013-03-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural Changes Associated with Peptide Lipidation Broaden Biological Function
To be Published

 

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