8G0E
 
 | | Cryo-EM structure of TBAJ-876-bound Mycobacterium smegmatis ATP synthase rotational state 3 | | Descriptor: | (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-2-(2,6-dimethoxypyridin-4-yl)-4-(dimethylamino)-1-(2,3,6-trimethoxypyridin-4-yl)butan-2-ol, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | | Authors: | Courbon, G.M, Rubinstein, J.L. | | Deposit date: | 2023-01-31 | | Release date: | 2023-02-15 | | Last modified: | 2023-08-09 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Mechanism of mycobacterial ATP synthase inhibition by squaramides and second generation diarylquinolines.
Embo J., 42, 2023
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8G0C
 | | Cryo-EM structure of TBAJ-876-bound Mycobacterium smegmatis ATP synthase rotational state 1 (backbone model) | | Descriptor: | (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-2-(2,6-dimethoxypyridin-4-yl)-4-(dimethylamino)-1-(2,3,6-trimethoxypyridin-4-yl)butan-2-ol, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | | Authors: | Courbon, G.M, Rubinstein, J.L. | | Deposit date: | 2023-01-31 | | Release date: | 2023-02-15 | | Last modified: | 2023-08-09 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Mechanism of mycobacterial ATP synthase inhibition by squaramides and second generation diarylquinolines.
Embo J., 42, 2023
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8G09
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8G0B
 | | Cryo-EM structure of TBAJ-876-bound Mycobacterium smegmatis ATP synthase FO region | | Descriptor: | (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-2-(2,6-dimethoxypyridin-4-yl)-4-(dimethylamino)-1-(2,3,6-trimethoxypyridin-4-yl)butan-2-ol, ATP synthase subunit a, ATP synthase subunit b, ... | | Authors: | Courbon, G.M, Rubinstein, J.L. | | Deposit date: | 2023-01-31 | | Release date: | 2023-02-15 | | Last modified: | 2023-08-09 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Mechanism of mycobacterial ATP synthase inhibition by squaramides and second generation diarylquinolines.
Embo J., 42, 2023
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8G07
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8G0A
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8G08
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8G0D
 | | Cryo-EM structure of TBAJ-876-bound Mycobacterium smegmatis ATP synthase rotational state 2 (backbone model) | | Descriptor: | (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-2-(2,6-dimethoxypyridin-4-yl)-4-(dimethylamino)-1-(2,3,6-trimethoxypyridin-4-yl)butan-2-ol, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | | Authors: | Courbon, G.M, Rubinstein, J.L. | | Deposit date: | 2023-01-31 | | Release date: | 2023-02-15 | | Last modified: | 2023-08-09 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Mechanism of mycobacterial ATP synthase inhibition by squaramides and second generation diarylquinolines.
Embo J., 42, 2023
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8FKJ
 | | Yeast ATP Synthase in conformation-3, at pH 6 | | Descriptor: | ATP synthase protein 8, ATP synthase subunit 4, mitochondrial, ... | | Authors: | Sharma, S, Patel, H, Luo, M, Mueller, D.M, Liao, M. | | Deposit date: | 2022-12-21 | | Release date: | 2024-01-24 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F 1 -F o coupling.
Nat.Struct.Mol.Biol., 2024
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8FL8
 | | Yeast ATP Synthase structure in presence of MgATP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase protein 8, ... | | Authors: | Sharma, S, Patel, H, Luo, M, Mueller, D.M, Liao, M. | | Deposit date: | 2022-12-21 | | Release date: | 2024-01-17 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F 1 -F o coupling.
Nat.Struct.Mol.Biol., 2024
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8F39
 | | Yeast ATP synthase in conformation-2, at pH 6 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP synthase protein 8, ATP synthase subunit 4, ... | | Authors: | Sharma, S, Patel, H, Luo, M, Mueller, D.M, Liao, M. | | Deposit date: | 2022-11-09 | | Release date: | 2024-02-07 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F 1 -F o coupling.
Nat.Struct.Mol.Biol., 2024
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8F29
 | | Yeast ATP synthase in conformation-1 at pH 6 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP synthase protein 8, ATP synthase subunit 4, ... | | Authors: | Sharma, S, Patel, H, Luo, M, Mueller, D.M, Liao, M. | | Deposit date: | 2022-11-07 | | Release date: | 2024-02-07 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F 1 -F o coupling.
Nat.Struct.Mol.Biol., 2024
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8H9U
 | | Human ATP synthase state 3a (combined) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F(0) complex subunit B1, ... | | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | | Deposit date: | 2022-10-25 | | Release date: | 2023-05-31 | | Last modified: | 2023-07-05 | | Method: | ELECTRON MICROSCOPY (2.61 Å) | | Cite: | Structure of the human ATP synthase.
Mol.Cell, 83, 2023
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8H9M
 | | Human ATP synthase state 3a subregion 3 | | Descriptor: | ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase F(0) complex subunit C1, ... | | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | | Deposit date: | 2022-10-25 | | Release date: | 2023-05-31 | | Last modified: | 2023-07-05 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structure of the human ATP synthase.
Mol.Cell, 83, 2023
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8H9J
 | | Human ATP synthase state2 subregion 3 | | Descriptor: | ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase F(0) complex subunit C1, ... | | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | | Deposit date: | 2022-10-25 | | Release date: | 2023-05-31 | | Last modified: | 2023-07-05 | | Method: | ELECTRON MICROSCOPY (3.26 Å) | | Cite: | Structure of the human ATP synthase.
Mol.Cell, 83, 2023
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8H9T
 | | Human ATP synthase state 2 (combined) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F(0) complex subunit B1, ... | | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | | Deposit date: | 2022-10-25 | | Release date: | 2023-05-31 | | Last modified: | 2023-07-05 | | Method: | ELECTRON MICROSCOPY (2.77 Å) | | Cite: | Structure of the human ATP synthase.
Mol.Cell, 83, 2023
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8H9Q
 | | Human ATP synthase state 3b subregion 3 | | Descriptor: | ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase F(0) complex subunit C1, ... | | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | | Deposit date: | 2022-10-25 | | Release date: | 2023-05-31 | | Last modified: | 2023-07-05 | | Method: | ELECTRON MICROSCOPY (3.47 Å) | | Cite: | Structure of the human ATP synthase.
Mol.Cell, 83, 2023
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8H9V
 | | Human ATP synthase state 3b (combined) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F(0) complex subunit B1, ... | | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | | Deposit date: | 2022-10-25 | | Release date: | 2023-05-31 | | Last modified: | 2023-07-05 | | Method: | ELECTRON MICROSCOPY (3.02 Å) | | Cite: | Structure of the human ATP synthase.
Mol.Cell, 83, 2023
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8H9S
 | | Human ATP synthase state 1 (combined) | | Descriptor: | 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | | Deposit date: | 2022-10-25 | | Release date: | 2023-05-31 | | Last modified: | 2023-07-05 | | Method: | ELECTRON MICROSCOPY (2.53 Å) | | Cite: | Structure of the human ATP synthase.
Mol.Cell, 83, 2023
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8H9F
 | | Human ATP synthase state 1 subregion 3 | | Descriptor: | 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, ATP synthase F(0) complex subunit B1, mitochondrial, ... | | Authors: | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | | Deposit date: | 2022-10-25 | | Release date: | 2023-08-30 | | Method: | ELECTRON MICROSCOPY (2.69 Å) | | Cite: | Structure of the human ATP synthase.
Mol.Cell, 83, 2023
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7Y5C
 | | Cryo-EM structure of F-ATP synthase from Mycolicibacterium smegmatis (rotational state 2) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | | Authors: | Saw, W.-G, Wong, C.F, Grueber, G. | | Deposit date: | 2022-06-16 | | Release date: | 2022-11-23 | | Last modified: | 2023-01-11 | | Method: | ELECTRON MICROSCOPY (4.7 Å) | | Cite: | Structural Elements Involved in ATP Hydrolysis Inhibition and ATP Synthesis of Tuberculosis and Nontuberculous Mycobacterial F-ATP Synthase Decipher New Targets for Inhibitors.
Antimicrob.Agents Chemother., 66, 2022
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7Y5D
 | | Cryo-EM structure of F-ATP synthase from Mycolicibacterium smegmatis (rotational state 3) (backbone) | | Descriptor: | ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit a, ... | | Authors: | Saw, W.-G, Wong, C.F, Grueber, G. | | Deposit date: | 2022-06-16 | | Release date: | 2022-11-23 | | Last modified: | 2023-01-11 | | Method: | ELECTRON MICROSCOPY (7.3 Å) | | Cite: | Structural Elements Involved in ATP Hydrolysis Inhibition and ATP Synthesis of Tuberculosis and Nontuberculous Mycobacterial F-ATP Synthase Decipher New Targets for Inhibitors.
Antimicrob.Agents Chemother., 66, 2022
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7Y5B
 | | Cryo-EM structure of F-ATP synthase from Mycolicibacterium smegmatis (rotational state 1) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | | Authors: | Saw, W.-G, Wong, C.F, Grueber, G. | | Deposit date: | 2022-06-16 | | Release date: | 2022-11-23 | | Last modified: | 2023-01-11 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Structural Elements Involved in ATP Hydrolysis Inhibition and ATP Synthesis of Tuberculosis and Nontuberculous Mycobacterial F-ATP Synthase Decipher New Targets for Inhibitors.
Antimicrob.Agents Chemother., 66, 2022
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8DBT
 | | E. coli ATP synthase imaged in 10mM MgATP State2 "down | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | | Authors: | Sobti, M, Stewart, A.G. | | Deposit date: | 2022-06-14 | | Release date: | 2023-01-25 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Changes within the central stalk of E. coli F 1 F o ATP synthase observed after addition of ATP.
Commun Biol, 6, 2023
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8DBQ
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