5O2L
| Myosin VI motor domain in the Pre-Transition State | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, GLYCEROL, ... | Authors: | Isabet, T, Benisty, H, Houdusse, A. | Deposit date: | 2017-05-22 | Release date: | 2018-05-23 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | An intermediate along the recovery stroke of myosin VI revealed by X-ray crystallography and molecular dynamics. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6I7D
| Plasmodium falciparum Myosin A, post-rigor and rigor-like states | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Myosin-A | Authors: | Robert-Paganin, J, Auguin, D, Moussaoui, D, Jousset, G, Baum, J, Trybus, K.M, Houdusse, A. | Deposit date: | 2018-11-16 | Release date: | 2019-08-07 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.82 Å) | Cite: | Plasmodium myosin A drives parasite invasion by an atypical force generating mechanism. Nat Commun, 10, 2019
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6DUE
| Toxoplasma gondii MyoA, a Class-XIV myosin, in the pre-powerstroke state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | Authors: | Powell, C.J, Boulanger, M.J. | Deposit date: | 2018-06-20 | Release date: | 2018-10-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural and mechanistic insights into the function of the unconventional class XIV myosin MyoA fromToxoplasma gondii. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6I7E
| Plasmodium falciparum Myosin A, Pre-powerstroke | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Myosin-A, ... | Authors: | Robert-Paganin, J, Auguin, D, Moussaoui, D, Jousset, G, Baum, J, Trybus, K.M, Houdusse, A. | Deposit date: | 2018-11-16 | Release date: | 2019-08-07 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.492 Å) | Cite: | Plasmodium myosin A drives parasite invasion by an atypical force generating mechanism. Nat Commun, 10, 2019
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4ZG4
| Myosin Vc Pre-powerstroke | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Ropars, V, Pylypenko, O, Sweeney, L, Houdusse, A. | Deposit date: | 2015-04-22 | Release date: | 2016-03-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Force-producing ADP state of myosin bound to actin. Proc.Natl.Acad.Sci.USA, 113, 2016
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5HMP
| Myosin Vc pre-powerstroke state | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, DIMETHYL SULFOXIDE, ... | Authors: | Ropars, V, Pylypenko, O, Sweeney, H.L, Houdusse, A. | Deposit date: | 2016-01-16 | Release date: | 2016-09-07 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.397 Å) | Cite: | The myosin X motor is optimized for movement on actin bundles. Nat Commun, 7, 2016
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1W8J
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4DBR
| Myosin VI D179Y (MD) pre-powerstroke state | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Pylypenko, O, Sweeney, H.L, Houdusse, A. | Deposit date: | 2012-01-16 | Release date: | 2013-01-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Mutations in myosin VI that cause a loss of coordination between heads provide insights into the structural changes underlying force generation and the importance of gating To be Published
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4PK4
| Myosin VI motor domain in the PPS state - from a Pi release state crystal, space group P212121 after long soaking with PO4 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Isabet, T, Benisty, H, Llinas, P, Sweeney, H.L, Houdusse, A. | Deposit date: | 2014-05-13 | Release date: | 2015-04-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | How actin initiates the motor activity of Myosin. Dev.Cell, 33, 2015
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4E7Z
| Myosin VI (MD) pre-powerstroke state, P21 crystal form | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | Authors: | Isabet, T, Sweeney, H.L, Houdusse, A. | Deposit date: | 2012-03-19 | Release date: | 2012-09-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Processive Steps in the Reverse Direction Require Uncoupling of the Lead Head Lever Arm of Myosin VI. Mol.Cell, 48, 2012
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4E7S
| Myosin VI D23R I24R R569E (MD) pre-powerstroke state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | Authors: | Isabet, T, Sweeney, H.L, Houdusse, A. | Deposit date: | 2012-03-19 | Release date: | 2012-09-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Processive Steps in the Reverse Direction Require Uncoupling of the Lead Head Lever Arm of Myosin VI. Mol.Cell, 48, 2012
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4PFO
| Myosin VI motor domain in the Pi release state, space group P212121 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | Authors: | Isabet, T, Benisty, H, Llinas, P, Sweeney, H.L, Houdusse, A. | Deposit date: | 2014-04-30 | Release date: | 2015-04-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | How actin initiates the motor activity of Myosin. Dev.Cell, 33, 2015
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4PJM
| Myosin VI motor domain in the Pi release state, space group P212121 - soaked with PO4 - located in the active site | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ISOPROPYL ALCOHOL, ... | Authors: | Isabet, T, Benisty, H, Llinas, P, Sweeney, H.L, Houdusse, A. | Deposit date: | 2014-05-12 | Release date: | 2015-04-29 | Last modified: | 2017-08-30 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | How actin initiates the motor activity of Myosin. Dev.Cell, 33, 2015
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4PFP
| Myosin VI motor domain in the Pi release state (with Pi) space group P21 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Isabet, T, Benisty, H, Llinas, P, Sweeney, H.L, Houdusse, A. | Deposit date: | 2014-04-30 | Release date: | 2015-04-29 | Last modified: | 2017-08-30 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | How actin initiates the motor activity of Myosin. Dev.Cell, 33, 2015
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4PJN
| Myosin VI motor domain in the Pi release state, space group P212121 - shortly soaked with PO4 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | Authors: | Isabet, T, Benisty, H, Llinas, P, Sweeney, H.L, Houdusse, A. | Deposit date: | 2014-05-12 | Release date: | 2015-04-29 | Last modified: | 2017-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | How actin initiates the motor activity of Myosin. Dev.Cell, 33, 2015
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4PJL
| Myosin VI motor domain A458E mutant in the Pi release state, space group P212121 - | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | Authors: | Isabet, T, Benisty, H, Llinas, P, Sweeney, H.L, Houdusse, A. | Deposit date: | 2014-05-12 | Release date: | 2015-04-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | How actin initiates the motor activity of Myosin. Dev.Cell, 33, 2015
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2V26
| Myosin VI (MD) pre-powerstroke state (Mg.ADP.VO4) | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Menetrey, J, Llinas, P, Mukherjea, M, Sweeney, H.L, Houdusse, A. | Deposit date: | 2007-06-03 | Release date: | 2007-11-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The Structural Basis for the Large Powerstroke of Myosin Vi. Cell(Cambridge,Mass.), 131, 2007
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1LKX
| MOTOR DOMAIN OF MYOE, A CLASS-I MYOSIN | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MYOSIN IE HEAVY CHAIN, ... | Authors: | Kollmar, M, Durrwang, U, Kliche, W, Manstein, D.J, Kull, F.J. | Deposit date: | 2002-04-26 | Release date: | 2002-06-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of the motor domain of a class-I myosin. EMBO J., 21, 2002
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1BR4
| SMOOTH MUSCLE MYOSIN MOTOR DOMAIN-ESSENTIAL LIGHT CHAIN COMPLEX WITH MGADP.BEF3 BOUND AT THE ACTIVE SITE | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | Authors: | Dominguez, R, Trybus, K.M, Cohen, C. | Deposit date: | 1998-08-27 | Release date: | 1998-09-09 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.62 Å) | Cite: | Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: visualization of the pre-power stroke state. Cell(Cambridge,Mass.), 94, 1998
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1B7T
| MYOSIN DIGESTED BY PAPAIN | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ... | Authors: | Houdusse, A, Kalabokis, V, Himmel, D, Szent-Gyorgyi, A.G, Cohen, C. | Deposit date: | 1999-01-15 | Release date: | 1999-05-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Atomic structure of scallop myosin subfragment S1 complexed with MgADP: a novel conformation of the myosin head. Cell(Cambridge,Mass.), 97, 1999
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6QDJ
| Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin | Descriptor: | 1,4-BUTANEDIOL, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Meinhart, A, Clausen, T, Arnese, R. | Deposit date: | 2019-01-02 | Release date: | 2019-10-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.884 Å) | Cite: | Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin. Nat Commun, 10, 2019
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6UI4
| Crystal structure of phenamacril-bound F. graminearum myosin I | Descriptor: | Calmodulin, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Zhou, Y, Zhou, X.E, Gong, Y, Zhu, Y, Xu, H.E, Zhou, M, Melcher, K, Zhang, F. | Deposit date: | 2019-09-30 | Release date: | 2020-03-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structural basis of Fusarium myosin I inhibition by phenamacril. Plos Pathog., 16, 2020
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7MF3
| Structure of the autoinhibited state of smooth muscle myosin-2 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Myosin light polypeptide 6, ... | Authors: | Heissler, S.M, Arora, A.S, Billington, N, Sellers, J.R, Chinthalapudi, K. | Deposit date: | 2021-04-08 | Release date: | 2022-01-05 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structure of the autoinhibited state of myosin-2. Sci Adv, 7, 2021
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8EXW
| Drosophila melanogaster indirect flight muscle myosin II (subfragment-1) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Isoform K of Myosin heavy chain, muscle, ... | Authors: | Caldwell, J.T, Huxford, T, Bernstein, S.I, Stec, B. | Deposit date: | 2022-10-25 | Release date: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Drosophila melanogaster indirect flight muscle myosin II (subfragment-1) To Be Published
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4ZLK
| Crystal structure of mouse myosin-5a in complex with calcium-bound calmodulin | Descriptor: | CALCIUM ION, Calmodulin, Unconventional myosin-Va | Authors: | Shen, M, Zhang, N, Zheng, S, Zhang, W.-B, Zhang, H.-M, Lu, Z, Su, Q.P, Sun, Y, Ye, K, Li, X.-D. | Deposit date: | 2015-05-01 | Release date: | 2016-05-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.502 Å) | Cite: | Structural basis for calcium regulation of myosin 5 motor function To Be Published
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