PDB: 187 resultsInfo pagesStatus searchChemie searchBIRD

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1BRI	BARNASE MUTANT WITH ILE 76 REPLACED BY ALA Descriptor: BARNASE Authors: Cramer, P.C, Buckle, A, Fersht, A. Deposit date: 1995-03-09 Release date: 1995-07-10 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities. Biochemistry, 35, 1996
1BNR	BARNASE Descriptor: BARNASE (G SPECIFIC ENDONUCLEASE) Authors: Bycroft, M. Deposit date: 1995-03-31 Release date: 1995-07-31 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Determination of the three-dimensional solution structure of barnase using nuclear magnetic resonance spectroscopy. Biochemistry, 30, 1991
1BNF	BARNASE T70C/S92C DISULFIDE MUTANT Descriptor: BARNASE Authors: Clarke, J, Henrick, K, Fersht, A.R. Deposit date: 1995-03-31 Release date: 1995-07-10 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Disulfide mutants of barnase. I: Changes in stability and structure assessed by biophysical methods and X-ray crystallography. J.Mol.Biol., 253, 1995
1BSA	CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE Descriptor: BARNASE Authors: Buckle, A.M, Henrick, K, Fersht, A.R. Deposit date: 1993-07-19 Release date: 1994-01-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structural analysis of mutations in the hydrophobic cores of barnase. J.Mol.Biol., 234, 1993
1BU4	RIBONUCLEASE 1 COMPLEX WITH 2'GMP Descriptor: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE T1 Authors: Loris, R, Devos, S, Langhorst, U, Decanniere, K, Bouckaert, J, Maes, D, Transue, T.R, Steyaert, J. Deposit date: 1998-09-11 Release date: 1999-02-16 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Conserved water molecules in a large family of microbial ribonucleases. Proteins, 36, 1999
1BUJ	STRUCTURE OF BINASE IN SOLUTION Descriptor: PROTEIN (BINASE) Authors: Reibarkh, M.Y, Nolde, D.E, Vasilieva, L.I, Arseniev, A.S. Deposit date: 1998-09-04 Release date: 1998-09-09 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Three-dimensional structure of binase in solution. FEBS Lett., 431, 1998
1BNJ	BARNASE WILDTYPE STRUCTURE AT PH 9.0 Descriptor: BARNASE Authors: Cameron, A, Henrick, K, Fersht, A.R, Dodson, G, Buckle, A.M. Deposit date: 1995-05-17 Release date: 1995-09-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structural analysis of mutations in the hydrophobic cores of barnase. J.Mol.Biol., 234, 1993
1BRK	BARNASE MUTANT WITH ILE 96 REPLACED BY ALA Descriptor: BARNASE, ZINC ION Authors: Cramer, P.C, Buckle, A, Fersht, A. Deposit date: 1995-03-09 Release date: 1995-07-10 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities. Biochemistry, 35, 1996
1BNE	BARNASE A43C/S80C DISULFIDE MUTANT Descriptor: BARNASE Authors: Clarke, J, Henrick, K, Fersht, A.R. Deposit date: 1995-03-31 Release date: 1995-07-10 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Disulfide mutants of barnase. I: Changes in stability and structure assessed by biophysical methods and X-ray crystallography. J.Mol.Biol., 253, 1995
1BNG	BARNASE S85C/H102C DISULFIDE MUTANT Descriptor: BARNASE Authors: Clarke, J, Henrick, K, Fersht, A.R. Deposit date: 1995-03-31 Release date: 1995-07-10 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Disulfide mutants of barnase. I: Changes in stability and structure assessed by biophysical methods and X-ray crystallography. J.Mol.Biol., 253, 1995
1BSD	CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE Descriptor: BARNASE Authors: Buckle, A.M, Henrick, K, Fersht, A.R. Deposit date: 1993-07-19 Release date: 1994-01-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structural analysis of mutations in the hydrophobic cores of barnase. J.Mol.Biol., 234, 1993
1BRG	CRYSTALLOGRAPHIC ANALYSIS OF PHE->LEU SUBSTITUTION IN THE HYDROPHOBIC CORE OF BARNASE Descriptor: BARNASE, ZINC ION Authors: Chen, Y.W, Fersht, A.R, Henrick, K. Deposit date: 1994-03-30 Release date: 1994-06-22 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystallographic analysis of Phe-->Leu substitution in the hydrophobic core of barnase. Acta Crystallogr.,Sect.D, 51, 1995
1BSB	CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE Descriptor: BARNASE Authors: Buckle, A.M, Henrick, K, Fersht, A.R. Deposit date: 1993-07-19 Release date: 1994-01-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structural analysis of mutations in the hydrophobic cores of barnase. J.Mol.Biol., 234, 1993
1B2Z	DELETION OF A BURIED SALT BRIDGE IN BARNASE Descriptor: PROTEIN (BARNASE), ZINC ION Authors: Vaughan, C.K, Harryson, P, Buckle, A.M, Oliveberg, M, Fersht, A.R. Deposit date: 1998-12-03 Release date: 1998-12-09 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.03 Å) Cite: A structural double-mutant cycle: estimating the strength of a buried salt bridge in barnase. Acta Crystallogr.,Sect.D, 58, 2002
1BOX	N39S MUTANT OF RNASE SA FROM STREPTOMYCES AUREOFACIENS Descriptor: GUANYL-SPECIFIC RIBONUCLEASE SA Authors: Hebert, E.J, Giletto, A, Sevcik, J, Urbanikova, L, Wilson, K.S, Dauter, Z, Pace, C.N. Deposit date: 1998-08-07 Release date: 1999-12-29 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Contribution of a conserved asparagine to the conformational stability of ribonucleases Sa, Ba, and T1. Biochemistry, 37, 1998
1BRN	SUBSITE BINDING IN AN RNASE: STRUCTURE OF A BARNASE-TETRANUCLEOTIDE COMPLEX AT 1.76 ANGSTROMS RESOLUTION Descriptor: DNA (5'-D(*CP*GP*AP*C)-3'), PROTEIN (BARNASE (E.C.3.1.27.-)) Authors: Buckle, A.M, Fersht, A.R. Deposit date: 1993-11-17 Release date: 1994-01-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.76 Å) Cite: Subsite binding in an RNase: structure of a barnase-tetranucleotide complex at 1.76-A resolution. Biochemistry, 33, 1994
1BSC	CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE Descriptor: BARNASE Authors: Buckle, A.M, Henrick, K, Fersht, A.R. Deposit date: 1993-07-19 Release date: 1994-01-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structural analysis of mutations in the hydrophobic cores of barnase. J.Mol.Biol., 234, 1993
1BVI	RIBONUCLEASE T1 (WILDTYPE) COMPLEXED WITH 2'GMP Descriptor: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, PROTEIN (RIBONUCLEASE T1) Authors: Langhorst, U, Loris, R, Denisov, V.P, Doumen, J, Roose, P, Maes, D, Halle, B, Steyaert, J. Deposit date: 1998-09-15 Release date: 1998-09-23 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Dissection of the structural and functional role of a conserved hydration site in RNase T1. Protein Sci., 8, 1999
1C54	SOLUTION STRUCTURE OF RIBONUCLEASE SA Descriptor: RIBONUCLEASE SA Authors: Laurents, D.V, Canadillas-Perez, J.M, Santoro, J, Schell, D, Pace, C.N, Rico, M, Bruix, M. Deposit date: 1999-10-22 Release date: 2001-11-28 Last modified: 2023-12-27 Method: SOLUTION NMR Cite: Solution structure and dynamics of ribonuclease Sa. Proteins, 44, 2001
1BNI	BARNASE WILDTYPE STRUCTURE AT PH 6.0 Descriptor: BARNASE Authors: Cameron, A, Henrick, K, Fersht, A.R, Dodson, G, Buckle, A.M. Deposit date: 1995-05-17 Release date: 1995-09-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structural analysis of mutations in the hydrophobic cores of barnase. J.Mol.Biol., 234, 1993
7MRX	Cryogenic crystal structure of barnase A43C/S80C bound to barstar C40A/C82A Descriptor: Barstar, Ribonuclease Authors: Caro, J.A, Smith, J, Wand, A.J. Deposit date: 2021-05-10 Release date: 2022-05-18 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Conformational entropy and protein affinity To Be Published
6PQK	Cryogenic crystal structure of barnase A43C/S80C bound to barstar C40A/S59C/A67C/C82A Descriptor: 1,2-ETHANEDIOL, Barstar, PHOSPHATE ION, ... Authors: Caro, J.A, Djanto, V, Wand, A.J. Deposit date: 2019-07-09 Release date: 2020-07-15 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Targeting conformational entropy to modulate binding affinity To Be Published
2ZA4	Crystal Structural Analysis of Barnase-barstar Complex Descriptor: Barstar, CHLORIDE ION, Ribonuclease Authors: Urakubo, Y, Ikura, T, Ito, N. Deposit date: 2007-10-01 Release date: 2008-05-20 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.58 Å) Cite: Crystal structural analysis of protein-protein interactions drastically destabilized by a single mutation Protein Sci., 17, 2008
3DA7	A conformationally strained, circular permutant of barnase Descriptor: Barnase circular permutant, Barstar Authors: Mitrousis, G, Butler, J, Loh, S.N, Cingolani, G. Deposit date: 2008-05-28 Release date: 2009-04-14 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structural and thermodynamic analysis of a conformationally strained circular permutant of barnase. Biochemistry, 48, 2009
1X1U	Water-mediate interaction at aprotein-protein interface Descriptor: Barstar, Ribonuclease Authors: Ikura, T, Urakubo, Y, Ito, N. Deposit date: 2005-04-13 Release date: 2005-04-26 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Water-mediated interaction at a protein-protein interface Chem.Phys., 307, 2004

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