1AMO
 
 | | THREE-DIMENSIONAL STRUCTURE OF NADPH-CYTOCHROME P450 REDUCTASE: PROTOTYPE FOR FMN-AND FAD-CONTAINING ENZYMES | | Descriptor: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Wang, M, Roberts, D.L, Paschke, R, Shea, T.M, Masters, B.S.S, Kim, J.J.P. | | Deposit date: | 1997-06-17 | | Release date: | 1998-06-17 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Three-dimensional structure of NADPH-cytochrome P450 reductase: prototype for FMN- and FAD-containing enzymes.
Proc.Natl.Acad.Sci.USA, 94, 1997
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8QT9
 | | Cryo-EM structure of stably reduced Streptococcus pneumoniae NADPH oxidase in complex with NADH | | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FAD-binding FR-type domain-containing protein, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Dubach, V.R.A, San Segundo-Acosta, P, Murphy, B.J. | | Deposit date: | 2023-10-12 | | Release date: | 2024-07-24 | | Last modified: | 2024-07-31 | | Method: | ELECTRON MICROSCOPY (2.36 Å) | | Cite: | Structural and mechanistic insights into Streptococcus pneumoniae NADPH oxidase.
Nat.Struct.Mol.Biol., 2024
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8QTA
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8QT6
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8QT7
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1A8P
 | | FERREDOXIN REDUCTASE FROM AZOTOBACTER VINELANDII | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, NADPH:FERREDOXIN OXIDOREDUCTASE | | Authors: | Prasad, G.S, Kresge, N, Muhlberg, A.B, Shaw, A, Jung, Y.S, Burgess, B.K, Stout, C.D. | | Deposit date: | 1998-03-28 | | Release date: | 1998-06-17 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The crystal structure of NADPH:ferredoxin reductase from Azotobacter vinelandii.
Protein Sci., 7, 1998
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1JA0
 | | CYPOR-W677X | | Descriptor: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Hubbard, P.A, Shen, A.L, Paschke, R, Kasper, C.B, Kim, J.J. | | Deposit date: | 2001-05-29 | | Release date: | 2001-08-22 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | NADPH-cytochrome P450 oxidoreductase. Structural basis for hydride and electron transfer.
J.Biol.Chem., 276, 2001
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1J9Z
 | | CYPOR-W677G | | Descriptor: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Hubbard, P.A, Shen, A.L, Paschke, R, Kasper, C.B, Kim, J.J. | | Deposit date: | 2001-05-29 | | Release date: | 2001-08-22 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | NADPH-cytochrome P450 oxidoreductase. Structural basis for hydride and electron transfer.
J.Biol.Chem., 276, 2001
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1JA1
 | | CYPOR-Triple Mutant | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Hubbard, P.A, Shen, A.L, Paschke, R, Kasper, C.B, Kim, J.J. | | Deposit date: | 2001-05-29 | | Release date: | 2001-08-22 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | NADPH-cytochrome P450 oxidoreductase. Structural basis for hydride and electron transfer.
J.Biol.Chem., 276, 2001
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4DQL
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1I7P
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4DQK
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4FK8
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4EH1
 | | Crystal Structure of the Flavohem-like-FAD/NAD Binding Domain of Nitric Oxide Dioxygenase from Vibrio cholerae O1 biovar El Tor | | Descriptor: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Flavohemoprotein, ... | | Authors: | Kim, Y, Gu, M, Hasseman, J, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2012-04-02 | | Release date: | 2012-04-25 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structure of the Flavohem-like-FAD/NAD Binding Domain of Nitric Oxide Dioxygenase from Vibrio cholerae O1 biovar El Tor
To be Published
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4F7D
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1QX4
 | | Structrue of S127P mutant of cytochrome b5 reductase | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, NADH-cytochrome b5 reductase | | Authors: | Bewley, M.C, Davis, C.A, Marohnic, C.C, Taormina, D, Barber, M.J. | | Deposit date: | 2003-09-04 | | Release date: | 2004-09-14 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The structure of the S127P mutant of cytochrome b5 reductase that causes methemoglobinemia shows the AMP moiety of the flavin occupying the substrate binding site
Biochemistry, 42, 2003
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4YAU
 | | Reduced CYPOR mutant - G141del/E142N | | Descriptor: | ADENOSINE-2'-MONOPHOSPHATE, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Xia, C, Kim, J.J.P. | | Deposit date: | 2015-02-17 | | Release date: | 2016-03-02 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
J.Biol.Chem., 291, 2016
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4Y9U
 | | rat CYPOR mutant - G143del | | Descriptor: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Xia, C, Kim, J.J.P. | | Deposit date: | 2015-02-17 | | Release date: | 2016-03-02 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
J.Biol.Chem., 291, 2016
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3W2I
 | | Crystal structure of re-oxidized form (60 min) of NADH-cytochrome b5 reductase from pig liver | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, NADH-cytochrome b5 reductase 3, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Yamada, M, Tamada, T, Matsumoto, F, Shoyama, Y, Kimura, S, Kuroki, R, Miki, K. | | Deposit date: | 2012-11-28 | | Release date: | 2013-07-17 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.81 Å) | | Cite: | Elucidations of the catalytic cycle of NADH-cytochrome b5 reductase by X-ray crystallography: new insights into regulation of efficient electron transfer
J.Mol.Biol., 425, 2013
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4YRY
 | | Insights into flavin-based electron bifurcation via the NADH-dependent reduced ferredoxin-NADP oxidoreductase structure | | Descriptor: | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit homolog, Dihydropyrimidine dehydrogenase subunit A, ... | | Authors: | Ermler, U, Thauer, R.K, Demmer, J.K, Huang, H, Wang, S, Demmer, U. | | Deposit date: | 2015-03-16 | | Release date: | 2015-07-08 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Insights into Flavin-based Electron Bifurcation via the NADH-dependent Reduced Ferredoxin:NADP Oxidoreductase Structure.
J.Biol.Chem., 290, 2015
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4YLF
 | | Insights into flavin-based electron bifurcation via the NADH-dependent reduced ferredoxin-NADP oxidoreductase structure | | Descriptor: | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit homolog, Dihydropyrimidine dehydrogenase subunit A, ... | | Authors: | Ermler, U, Thauer, R.K, Demmer, J.K, Huang, H, Wang, S, Demmer, U. | | Deposit date: | 2015-03-05 | | Release date: | 2015-07-08 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.301 Å) | | Cite: | Insights into Flavin-based Electron Bifurcation via the NADH-dependent Reduced Ferredoxin:NADP Oxidoreductase Structure.
J.Biol.Chem., 290, 2015
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4Y9R
 | | rat CYPOR mutant - G141del | | Descriptor: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Xia, C, Kim, J.J.P. | | Deposit date: | 2015-02-17 | | Release date: | 2016-03-02 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
J.Biol.Chem., 291, 2016
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4YAL
 | | Reduced CYPOR with 2'-AMP | | Descriptor: | ADENOSINE-2'-MONOPHOSPHATE, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Xia, C, Kim, J.J.P. | | Deposit date: | 2015-02-17 | | Release date: | 2016-03-02 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
J.Biol.Chem., 291, 2016
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4YAO
 | | Reduced CYPOR mutant - G143del | | Descriptor: | ADENOSINE-2'-MONOPHOSPHATE, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Xia, C, Kim, J.J.P. | | Deposit date: | 2015-02-17 | | Release date: | 2016-03-02 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
J.Biol.Chem., 291, 2016
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4YAF
 | | rat CYPOR with 2'-AMP | | Descriptor: | ADENOSINE-2'-MONOPHOSPHATE, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Xia, C, Kim, J.J.P. | | Deposit date: | 2015-02-17 | | Release date: | 2016-03-09 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
J.Biol.Chem., 291, 2016
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