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8VHN	Crystal Structure of E. coli class Ia ribonucleotide reductase alpha subunit bound to two ATP molecules Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, ... Authors: Funk, M.A, Zimanyi, C.M, Drennan, C.L. Deposit date: 2024-01-02 Release date: 2024-09-04 Method: X-RAY DIFFRACTION (2.62 Å) Cite: How ATP and dATP Act as Molecular Switches to Regulate Enzymatic Activity in the Prototypical Bacterial Class Ia Ribonucleotide Reductase. Biochemistry, 2024
8VHU	Crystal structure of dATP bound E. coli class Ia ribonucleotide reductase alpha construct fused with the C-terminal tail of E. coli class Ia beta subunit Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CHLORIDE ION, Fusion protein of Ribonucleoside-diphosphate reductase 1 subunits alpha and beta, ... Authors: Funk, M.A, Zimanyi, C.M, Drennan, C.L. Deposit date: 2024-01-02 Release date: 2024-09-04 Method: X-RAY DIFFRACTION (2.1 Å) Cite: How ATP and dATP Act as Molecular Switches to Regulate Enzymatic Activity in the Prototypical Bacterial Class Ia Ribonucleotide Reductase. Biochemistry, 2024
3TB9	Structure of Yeast Ribonucleotide Reductase 1 Q288A with AMPPNP and CDP Descriptor: CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... Authors: Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C.D. Deposit date: 2011-08-05 Release date: 2012-04-04 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.53 Å) Cite: Role of Arginine 293 and Glutamine 288 in Communication between Catalytic and Allosteric Sites in Yeast Ribonucleotide Reductase. J.Mol.Biol., 419, 2012
3S87	Structure of Yeast Ribonucleotide Reductase 1 with dGTP and ADP Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C.D. Deposit date: 2011-05-27 Release date: 2012-04-11 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structural and biochemical basis of lethal mutant R293A of yeast ribonucleotide reductase To be Published
3TBA	Structure of Yeast Ribonucleotide Reductase 1 Q288A with dGTP and ADP Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C. Deposit date: 2011-08-05 Release date: 2012-04-04 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Role of Arginine 293 and Glutamine 288 in Communication between Catalytic and Allosteric Sites in Yeast Ribonucleotide Reductase. J.Mol.Biol., 419, 2012
3S8B	Structure of Yeast Ribonucleotide Reductase 1 with AMPPNP and CDP Descriptor: CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... Authors: Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C.D. Deposit date: 2011-05-27 Release date: 2012-04-11 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural and biochemical basis of lethal mutant R293A of yeast ribonucleotide reductase To be Published
3UUS	Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, FE (III) ION, Ribonucleoside-diphosphate reductase 1 subunit alpha, ... Authors: Zimanyi, C.M, Drennan, C.L. Deposit date: 2011-11-28 Release date: 2011-12-21 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (5.65 Å) Cite: Structural interconversions modulate activity of Escherichia coli ribonucleotide reductase. Proc.Natl.Acad.Sci.USA, 108, 2011
3S8C	Structure of Yeast Ribonucleotide Reductase 1 R293A with AMPPNP and CDP Descriptor: CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... Authors: Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C.D. Deposit date: 2011-05-27 Release date: 2012-04-11 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.77 Å) Cite: Structural and biochemical basis of lethal mutant R293A of yeast ribonucleotide reductase To be Published
3S8A	Structure of Yeast Ribonucleotide Reductase R293A with dGTP Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large chain 1 Authors: Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C.D. Deposit date: 2011-05-27 Release date: 2012-04-11 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural and biochemical basis of lethal mutant R293A of yeast ribonucleotide reductase To be Published
2CVX	Structures of Yeast Ribonucleotide Reductase I Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-14 Release date: 2006-03-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVT	Structures of Yeast Ribonucleotide Reductase I Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribonucleoside-diphosphate reductase large chain 1 Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-14 Release date: 2006-03-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVV	Structures of Yeast Ribonucleotide Reductase I Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribonucleoside-diphosphate reductase large chain 1, ... Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-14 Release date: 2006-03-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
2XAW	Ribonucleotide reductase Y730NO2Y and Y731F modified R1 subunit of E. coli Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA Authors: Yokoyama, K, Uhlin, U, Stubbe, J. Deposit date: 2010-03-31 Release date: 2010-04-14 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase. J.Am.Chem.Soc., 132, 2010
2XAY	Ribonucleotide reductase Y730NO2Y and C439A modified R1 subunit of E. coli Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA Authors: Yokoyama, K, Uhlin, U, Stubbe, J. Deposit date: 2010-04-01 Release date: 2010-04-14 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase. J.Am.Chem.Soc., 132, 2010
2CVU	Structures of Yeast Ribonucleotide Reductase I Descriptor: CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-14 Release date: 2006-03-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVS	Structures of Yeast Ribonucleotide Reductase I Descriptor: Ribonucleoside-diphosphate reductase large chain 1 Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-14 Release date: 2006-03-07 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
2XAZ	Ribonucleotide reductase Y730NO2Y and C439S modified R1 subunit of E. coli Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA Authors: Yokoyama, K, Uhlin, U, Stubbe, J. Deposit date: 2010-04-01 Release date: 2010-04-14 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase. J.Am.Chem.Soc., 132, 2010
2EUD	Structures of Yeast Ribonucleotide Reductase I complexed with Ligands and Subunit Peptides Descriptor: GEMCITABINE DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... Authors: Dealwis, C, Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J. Deposit date: 2005-10-28 Release date: 2006-03-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structures of eukaryotic ribonucleotide reductase I define gemcitabine diphosphate binding and subunit assembly. Proc.Natl.Acad.Sci.Usa, 103, 2006
2R1R	RIBONUCLEOTIDE REDUCTASE R1 PROTEIN WITH DTTP OCCUPYING THE SPECIFICITY SITE FROM ESCHERICHIA COLI Descriptor: RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, RIBONUCLEOTIDE REDUCTASE R2 PROTEIN, THYMIDINE-5'-TRIPHOSPHATE Authors: Eriksson, M, Eklund, H. Deposit date: 1997-07-21 Release date: 1998-01-28 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (3 Å) Cite: Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding. Structure, 5, 1997
2XAV	Ribonucleotide reductase Y731NO2Y and Y730F modified R1 subunit of E. coli Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA Authors: Yokoyama, K, Uhlin, U, Stubbe, J. Deposit date: 2010-03-31 Release date: 2010-04-14 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase. J.Am.Chem.Soc., 132, 2010
2X0X	Ribonucleotide reductase R1 subunit of E. coli to 2.3 A resolution Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA, SULFATE ION Authors: Yokoyama, K, Uhlin, U, Stubbe, J. Deposit date: 2009-12-18 Release date: 2010-01-26 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase. J.Am.Chem.Soc., 132, 2010
2XAX	Ribonucleotide reductase Y730NO2Y and Y731A modified R1 subunit of E. coli Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA Authors: Yokoyama, K, Uhlin, U, Stubbe, J. Deposit date: 2010-04-01 Release date: 2010-04-14 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase. J.Am.Chem.Soc., 132, 2010
2CVY	Structures of Yeast Ribonucleotide Reductase I Descriptor: 9-per peptide from Ribonucleoside-diphosphate reductase small chain 1, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large chain 1, ... Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-14 Release date: 2006-03-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVW	Structures of Yeast Ribonucleotide Reductase I Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large chain 1, ... Authors: Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. Deposit date: 2005-06-14 Release date: 2006-03-07 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation Proc.Natl.Acad.Sci.Usa, 103, 2006
2XAK	Ribonucleotide reductase Y730NO2Y modified R1 subunit of E. coli Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA Authors: Yokoyama, K, Uhlin, U, Stubbe, J. Deposit date: 2010-03-31 Release date: 2010-04-14 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase. J.Am.Chem.Soc., 132, 2010

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