5Z5A
| Crystal structure of Tk-PTP in the active form | Descriptor: | Protein-tyrosine phosphatase, VANADATE ION | Authors: | Ku, B, Yun, H.Y, Kim, S.J. | Deposit date: | 2018-01-17 | Release date: | 2018-07-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural study reveals the temperature-dependent conformational flexibility of Tk-PTP, a protein tyrosine phosphatase from Thermococcus kodakaraensis KOD1 PLoS ONE, 13, 2018
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5Z59
| Crystal structure of Tk-PTP in the inactive form | Descriptor: | Protein-tyrosine phosphatase | Authors: | Ku, B, Yun, H.Y, Kim, S.J. | Deposit date: | 2018-01-17 | Release date: | 2018-06-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.703 Å) | Cite: | Structural study reveals the temperature-dependent conformational flexibility of Tk-PTP, a protein tyrosine phosphatase from Thermococcus kodakaraensis KOD1 PLoS ONE, 13, 2018
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5Z5B
| Crystal structure of Tk-PTP in the G95A mutant form | Descriptor: | CHLORIDE ION, FORMIC ACID, Protein-tyrosine phosphatase | Authors: | Ku, B, Yun, H.Y, Kim, S.J. | Deposit date: | 2018-01-17 | Release date: | 2018-06-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural study reveals the temperature-dependent conformational flexibility of Tk-PTP, a protein tyrosine phosphatase from Thermococcus kodakaraensis KOD1 PLoS ONE, 13, 2018
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5XJV
| Two intermediate states of conformation switch in dual specificity phosphatase 13a | Descriptor: | Dual specificity protein phosphatase 13 isoform A, PHOSPHATE ION | Authors: | Wei, C.H, Min, H.G, Chun, H.J, Ryu, S.E. | Deposit date: | 2017-05-04 | Release date: | 2018-04-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Two intermediate states of the conformational switch in dual specificity phosphatase 13a Pharmacol. Res., 128, 2018
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5Y15
| Crystal structure of human DUSP28 | Descriptor: | Dual specificity phosphatase 28, PHOSPHATE ION | Authors: | Ku, B, Hong, W, Kim, S.J, Ryu, S.E. | Deposit date: | 2017-07-19 | Release date: | 2017-11-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and biochemical analysis of atypically low dephosphorylating activity of human dual-specificity phosphatase 28 PLoS ONE, 12, 2017
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5Y16
| Crystal structure of human DUSP28(Y102H) | Descriptor: | CHLORIDE ION, Dual specificity phosphatase 28, PHOSPHATE ION | Authors: | Ku, B, Kim, M, Kim, S.J, Ryu, S.E. | Deposit date: | 2017-07-19 | Release date: | 2017-11-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.399 Å) | Cite: | Structural and biochemical analysis of atypically low dephosphorylating activity of human dual-specificity phosphatase 28 PLoS ONE, 12, 2017
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6APX
| Crystal structure of human dual specificity phosphatase 1 catalytic domain (C258S) as a maltose binding protein fusion in complex with the monobody YSX1 | Descriptor: | GLYCEROL, Maltose-binding periplasmic protein,Dual specificity protein phosphatase 1, Monobody YSX1, ... | Authors: | Gumpena, R, Lountos, G.T, Sreejith, R.K, Tropea, J.E, Cherry, S, Waugh, D.S. | Deposit date: | 2017-08-18 | Release date: | 2017-11-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.491 Å) | Cite: | Crystal structure of the human dual specificity phosphatase 1 catalytic domain. Protein Sci., 27, 2018
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5NCR
| OH1 from the Orf virus: a tyrosine phosphatase that displays distinct structural features and triple substrate specificity | Descriptor: | PHOSPHATE ION, SULFATE ION, tyrosine phosphatase | Authors: | Segovia, D, Haouz, A, Berois, M, Villarino, A, Andre-Leroux, G. | Deposit date: | 2017-03-06 | Release date: | 2017-08-09 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | OH1 from Orf Virus: A New Tyrosine Phosphatase that Displays Distinct Structural Features and Triple Substrate Specificity. J. Mol. Biol., 429, 2017
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5XW4
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5XW5
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5M43
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5GTJ
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4YR8
| Crystal structure of JNK in complex with a regulator protein | Descriptor: | CHLORIDE ION, Dual specificity protein phosphatase 16, Mitogen-activated protein kinase 8 | Authors: | Liu, X, Wang, J, Wu, J.W, Wang, Z.X. | Deposit date: | 2015-03-14 | Release date: | 2016-03-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation. Nat Commun, 7, 2016
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4D3R
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4D3P
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4D3Q
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4Y2E
| Crystal structure of the catalytic domain of human dual-specificity phosphatase 7 (C232S) | Descriptor: | Dual specificity protein phosphatase 7, PHOSPHATE ION | Authors: | Lountos, G.T, Austin, B.P, Tropea, J.E, Waugh, D.S. | Deposit date: | 2015-02-09 | Release date: | 2015-06-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Structure of human dual-specificity phosphatase 7, a potential cancer drug target. Acta Crystallogr.,Sect.F, 71, 2015
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4WOH
| Structure of of human dual-specificity phosphatase 22 (E24A/K28A/K30A/C88S) complexed with 4-nitrophenolphosphate | Descriptor: | 1,2-ETHANEDIOL, 4-NITROPHENYL PHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | Authors: | Lountos, G.T, Cherry, S, Tropea, J.E, Waugh, D.S. | Deposit date: | 2014-10-15 | Release date: | 2015-02-18 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | Structural analysis of human dual-specificity phosphatase 22 complexed with a phosphotyrosine-like substrate. Acta Crystallogr.,Sect.F, 71, 2015
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4RKK
| Structure of a product bound phosphatase | Descriptor: | Laforin, PHOSPHATE ION, alpha-D-glucopyranose, ... | Authors: | Vander Kooi, C.W. | Deposit date: | 2014-10-13 | Release date: | 2015-01-07 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural mechanism of laforin function in glycogen dephosphorylation and lafora disease. Mol.Cell, 57, 2015
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4R30
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4PYH
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4JNB
| Crystal structure of the Catalytic Domain of Human DUSP12 | Descriptor: | Dual specificity protein phosphatase 12, SULFATE ION | Authors: | Jeon, T.J, Chien, P.N, Ku, B, Kim, S.J, Ryu, S.E. | Deposit date: | 2013-03-15 | Release date: | 2014-03-26 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The family-wide structure and function of human dual-specificity protein phosphatases. Acta Crystallogr.,Sect.D, 70, 2014
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4KI9
| Crystal structure of the catalytic domain of human DUSP12 at 2.0 A resolution | Descriptor: | Dual specificity protein phosphatase 12, PHOSPHATE ION | Authors: | Jeon, T.J, Chien, P.N, Ku, B, Kim, S.J, Ryu, S.E. | Deposit date: | 2013-05-02 | Release date: | 2014-02-26 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The family-wide structure and function of human dual-specificity protein phosphatases Acta Crystallogr.,Sect.D, 70, 2014
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4JMJ
| Structure of dusp11 | Descriptor: | CHLORIDE ION, PHOSPHATE ION, RNA/RNP complex-1-interacting phosphatase | Authors: | Jeong, D.G, Kim, S.J, Ryu, S.E. | Deposit date: | 2013-03-14 | Release date: | 2014-02-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.382 Å) | Cite: | The family-wide structure and function of human dual-specificity protein phosphatases. Acta Crystallogr.,Sect.D, 70, 2014
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4JMK
| Structure of dusp8 | Descriptor: | Dual specificity protein phosphatase 8, SULFATE ION | Authors: | Jeong, D.G, Kim, S.J, Ryu, S.E. | Deposit date: | 2013-03-14 | Release date: | 2014-02-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The family-wide structure and function of human dual-specificity protein phosphatases. Acta Crystallogr.,Sect.D, 70, 2014
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