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5ET5
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Human muscle fructose-1,6-bisphosphatase in active R-state
Descriptor: Fructose-1,6-bisphosphatase isozyme 2
Authors:Barciszewski, J, Wisniewski, J, Kolodziejczyk, R, Dzugaj, A, Jaskolski, M, Rakus, D.
Deposit date:2015-11-17
Release date:2016-04-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:T-to-R switch of muscle fructose-1,6-bisphosphatase involves fundamental changes of secondary and quaternary structure.
Acta Crystallogr D Struct Biol, 72, 2016
5ET8
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Human muscle fructose-1,6-bisphosphatase in active R-state in complex with fructose-6-phosphate
Descriptor: 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase isozyme 2
Authors:Barciszewski, J, Wisniewski, J, Kolodziejczyk, R, Dzugaj, A, Jaskolski, M, Rakus, D.
Deposit date:2015-11-17
Release date:2016-11-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:T-to-R switch of muscle FBPase involves extreme changes of secondary and quaternary structure
To Be Published
5ET6
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Human muscle fructose-1,6-bisphosphatase in inactive T-state in complex with AMP
Descriptor: ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase isozyme 2
Authors:Barciszewski, J, Wisniewski, J, Kolodziejczyk, R, Dzugaj, A, Jaskolski, M, Rakus, D.
Deposit date:2015-11-17
Release date:2016-04-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.845 Å)
Cite:T-to-R switch of muscle fructose-1,6-bisphosphatase involves fundamental changes of secondary and quaternary structure.
Acta Crystallogr D Struct Biol, 72, 2016
5ET7
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Human muscle fructose-1,6-bisphosphatase in inactive T-state
Descriptor: Fructose-1,6-bisphosphatase isozyme 2
Authors:Barciszewski, J, Wisniewski, J, Kolodziejczyk, R, Dzugaj, A, Jaskolski, M, Rakus, D.
Deposit date:2015-11-17
Release date:2016-04-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.989 Å)
Cite:T-to-R switch of muscle fructose-1,6-bisphosphatase involves fundamental changes of secondary and quaternary structure.
Acta Crystallogr D Struct Biol, 72, 2016
5FBP
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BU of 5fbp by Molmil
CRYSTAL STRUCTURE OF THE NEUTRAL FORM OF FRUCTOSE-1,6-BISPHOSPHATASE COMPLEXED WITH THE PRODUCT FRUCTOSE 6-PHOSPHATE AT 2.1-ANGSTROMS RESOLUTION
Descriptor: 6-O-phosphono-beta-D-fructofuranose, FRUCTOSE 1,6-BISPHOSPHATASE
Authors:Ke, H, Liang, J.-Y, Zhang, Y, Lipscomb, W.N.
Deposit date:1991-02-11
Release date:1992-07-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the neutral form of fructose-1,6-bisphosphatase complexed with the product fructose 6-phosphate at 2.1-A resolution.
Proc.Natl.Acad.Sci.USA, 88, 1991
5K56
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BU of 5k56 by Molmil
Human muscle fructose-1,6-bisphosphatase in active R-state in complex with fructose-1,6-bisphosphate
Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase isozyme 2
Authors:Barciszewski, J, Wisniewski, J, Kolodziejczyk, R, Dzugaj, A, Jaskolski, M, Rakus, D.
Deposit date:2016-05-23
Release date:2017-06-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.198 Å)
Cite:Structural studies of human muscle FBPase
To Be Published
5K54
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Human muscle fructose-1,6-bisphosphatase E69Q mutant in active R-state
Descriptor: Fructose-1,6-bisphosphatase isozyme 2
Authors:Barciszewski, J, Wisniewski, J, Kolodziejczyk, R, Dzugaj, A, Jaskolski, M, Rakus, D.
Deposit date:2016-05-23
Release date:2017-06-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.717 Å)
Cite:Structural studies of human muscle FBPase
To Be Published
2QVV
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Porcine Liver Fructose-1,6-bisphosphatase cocrystallized with Fru-2,6-P2 and Zn2+, I(T)-state
Descriptor: 2,6-di-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase 1, PHOSPHATE ION, ...
Authors:Hines, J.K, Chen, X, Nix, J.C, Fromm, H.J, Honzatko, R.B.
Deposit date:2007-08-08
Release date:2007-10-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structures of mammalian and bacterial fructose-1,6-bisphosphatase reveal the basis for synergism in AMP/fructose 2,6-bisphosphate inhibition
J.Biol.Chem., 282, 2007
5L0A
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BU of 5l0a by Molmil
Human muscle fructose-1,6-bisphosphatase E69Q mutant in active R-state in complex with fructose-1,6-bisphosphate
Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase isozyme 2
Authors:Barciszewski, J, Wisniewski, J, Kolodziejczyk, R, Dzugaj, A, Jaskolski, M, Rakus, D.
Deposit date:2016-07-27
Release date:2017-08-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.302 Å)
Cite:Structural studies of human muscle FBPase
To Be Published
5IZ1
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Physcomitrella patens FBPase
Descriptor: fructose-1,6-bisphosphatase
Authors:Einsle, O, Guetle, D.
Deposit date:2016-03-24
Release date:2016-06-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Chloroplast FBPase and SBPase are thioredoxin-linked enzymes with similar architecture but different evolutionary histories.
Proc.Natl.Acad.Sci.USA, 113, 2016
5K55
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BU of 5k55 by Molmil
Human muscle fructose-1,6-bisphosphatase E69Q mutant in active R-state in complex with fructose-6-phosphate
Descriptor: 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase isozyme 2
Authors:Barciszewski, J, Wisniewski, J, Kolodziejczyk, R, Dzugaj, A, Jaskolski, M, Rakus, D.
Deposit date:2016-05-23
Release date:2017-06-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.977 Å)
Cite:Structural studies of human muscle FBPase
To Be Published
2WBD
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BU of 2wbd by Molmil
FRUCTOSE-1,6-BISPHOSPHATASE(D-FRUCTOSE-1,6-BISPHOSPHATE-1- PHOSPHOHYDROLASE) (E.C.3.1.3.11) COMPLEXED WITH AN AMP SITE INHIBITOR
Descriptor: FRUCTOSE-1,6-BISPHOSPHATASE 1, N-[(5-bromo-1,3-thiazol-2-yl)carbamoyl]-3-ethylbenzenesulfonamide
Authors:Ruf, A, Joseph, C, Benz, J, Fol, B, Tetaz, T, Kitas, E, Mohr, P, Kuhn, B, Wessel, H.P, Hebeisen, P, Haap, W, Huber, W, Alvarez Sanchez, R, Paehler, A, Bernadeau, A, Gubler, M, Schott, B, Tozzo, E.
Deposit date:2009-02-26
Release date:2009-12-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Sulfonylureido Thiazoles as Fructose-1,6-Bisphosphatase Inhibitors for the Treatment of Type-2 Diabetes.
Bioorg.Med.Chem.Lett., 20, 2010
2VT5
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FRUCTOSE-1,6-BISPHOSPHATASE(D-FRUCTOSE-1,6-BISPHOSPHATE -1- PHOSPHOHYDROLASE) (E.C.3.1.3.11) COMPLEXED WITH A DUAL BINDING AMP SITE INHIBITOR
Descriptor: 4-AMINO-N-[(2-SULFANYLETHYL)CARBAMOYL]BENZENESULFONAMIDE, FRUCTOSE-1,6-BISPHOSPHATASE 1
Authors:Ruf, A, Joseph, C, Benz, J, Fol, B, Tetaz, T.
Deposit date:2008-05-09
Release date:2008-07-22
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Allosteric Fbpase Inhibitors Gain 10(5) Times in Potency When Simultaneously Binding Two Neighboring AMP Sites.
Bioorg.Med.Chem.Lett., 18, 2008
2WBB
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BU of 2wbb by Molmil
FRUCTOSE-1,6-BISPHOSPHATASE(D-FRUCTOSE-1,6-BISPHOSPHATE-1- PHOSPHOHYDROLASE) (E.C.3.1.3.11) COMPLEXED WITH AN AMP SITE INHIBITOR
Descriptor: FRUCTOSE-1,6-BISPHOSPHATASE 1, N-{[(2Z)-5-BROMO-1,3-THIAZOL-2(3H)-YLIDENE]CARBAMOYL}-4-METHYLBENZENESULFONAMIDE
Authors:Ruf, A, Joseph, C, Benz, J, Fol, B, Tetaz, T, Kitas, E, Mohr, P, Kuhn, B, Wessel, H.P, Hebeisen, P, Haap, W, Huber, W, Alvarez Sanchez, R, Paehler, A, Bernadeau, A, Gubler, M, Schott, B, Tozzo, E.
Deposit date:2009-02-26
Release date:2009-12-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Sulfonylureido Thiazoles as Fructose-1,6-Bisphosphatase Inhibitors for the Treatment of Type-2 Diabetes.
Bioorg.Med.Chem.Lett., 20, 2010
5LDZ
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BU of 5ldz by Molmil
Quadruple space group ambiguity due to rotational and translational non-crystallographic symmetry in human liver fructose-1,6-bisphosphatase
Descriptor: CHLORIDE ION, Fructose-1,6-bisphosphatase 1, SULFATE ION, ...
Authors:Ruf, A, Tetaz, T, Schott, B, Joseph, C, Rudolph, M.G.
Deposit date:2016-06-29
Release date:2016-10-26
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Quadruple space-group ambiguity owing to rotational and translational noncrystallographic symmetry in human liver fructose-1,6-bisphosphatase.
Acta Crystallogr D Struct Biol, 72, 2016
2QVU
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BU of 2qvu by Molmil
Porcine Liver Fructose-1,6-bisphosphatase cocrystallized with Fru-2,6-P2 and Mg2+, I(T)-state
Descriptor: 2,6-di-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase 1, MAGNESIUM ION, ...
Authors:Hines, J.K, Chen, X, Nix, J.C, Fromm, H.J, Honzatko, R.B.
Deposit date:2007-08-08
Release date:2007-10-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structures of mammalian and bacterial fructose-1,6-bisphosphatase reveal the basis for synergism in AMP/fructose 2,6-bisphosphate inhibition
J.Biol.Chem., 282, 2007
2QVR
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BU of 2qvr by Molmil
E. coli Fructose-1,6-bisphosphatase: Citrate, Fru-2,6-P2, and Mg2+ bound
Descriptor: 2,6-di-O-phosphono-beta-D-fructofuranose, CITRIC ACID, Fructose-1,6-bisphosphatase, ...
Authors:Hines, J.K, Fromm, H.J, Honzatko, R.B.
Deposit date:2007-08-08
Release date:2007-10-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Structures of Mammalian and Bacterial Fructose-1,6-bisphosphatase Reveal the Basis for Synergism in AMP/Fructose 2,6-Bisphosphate Inhibition.
J.Biol.Chem., 282, 2007
4IR8
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BU of 4ir8 by Molmil
1.85 Angstrom Crystal Structure of Putative Sedoheptulose-1,7 bisphosphatase from Toxoplasma gondii
Descriptor: ACETATE ION, DI(HYDROXYETHYL)ETHER, Sedoheptulose-1,7 bisphosphatase, ...
Authors:Minasov, G, Ruan, J, Wawrzak, Z, Halavaty, A, Shuvalova, L, Harb, O.S, Ngo, H, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-01-14
Release date:2013-01-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:1.85 Angstrom Crystal Structure of Putative Sedoheptulose-1,7 bisphosphatase from Toxoplasma gondii.
TO BE PUBLISHED
4GWU
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BU of 4gwu by Molmil
Crystal Structure of Fru 2,6-bisphosphate complexes of Porcine Liver Fructose-1,6-bisphosphatase with Filled Central Cavity
Descriptor: 2,6-di-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase 1, MAGNESIUM ION
Authors:Gao, Y, Honzatko, R.B.
Deposit date:2012-09-03
Release date:2013-09-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Hydrophobic Central Cavity in Fructose-1,6-bisphosphatase is Essential for the Synergism in AMP/Fru 2,6-bisphosphate Inhibition
To be Published
4GWY
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BU of 4gwy by Molmil
Crystal Structure of AMP Complexes of Porcine Liver Fructose-1,6-bisphosphatase with Blocked Subunit Pair Rotation
Descriptor: 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase 1, ...
Authors:Gao, Y, Honzatko, R.B.
Deposit date:2012-09-03
Release date:2013-09-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Functional Importance of Subunit Pair Rotation in Regulation of Tetrameric Mammalian Fructose-1,6-bisphosphatase
To be Published
4HE2
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BU of 4he2 by Molmil
Crystal structure of human muscle fructose-1,6-bisphosphatase Q32R mutant complex with AMP
Descriptor: ADENOSINE MONOPHOSPHATE, CHLORIDE ION, Fructose-1,6-bisphosphatase isozyme 2, ...
Authors:Shi, R, Zhu, D.W, Lin, S.X.
Deposit date:2012-10-03
Release date:2013-10-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structures of Human Muscle Fructose-1,6-Bisphosphatase: Novel Quaternary States, Enhanced AMP Affinity, and Allosteric Signal Transmission Pathway.
Plos One, 8, 2013
4H45
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Product Complexes of Porcine Liver Fructose-1,6-bisphosphatase with Mutation E192Q
Descriptor: 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase 1, PHOSPHATE ION, ...
Authors:Gao, Y, Honzatko, R.B.
Deposit date:2012-09-16
Release date:2013-09-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Dimer-dimer Interface in Porcine Liver Fructose-1,6-bisphosphatase is Essential in Cooperative Binding of AMP
To be Published
4HE1
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BU of 4he1 by Molmil
Crystal structure of human muscle fructose-1,6-bisphosphatase Q32R mutant complex with fructose-6-phosphate and phosphate
Descriptor: 6-O-phosphono-beta-D-fructofuranose, CHLORIDE ION, Fructose-1,6-bisphosphatase isozyme 2, ...
Authors:Shi, R, Zhu, D.W, Lin, S.X.
Deposit date:2012-10-03
Release date:2013-10-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Crystal Structures of Human Muscle Fructose-1,6-Bisphosphatase: Novel Quaternary States, Enhanced AMP Affinity, and Allosteric Signal Transmission Pathway.
Plos One, 8, 2013
4H46
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BU of 4h46 by Molmil
Crystal Structure of AMP complexes of NEM modified Porcine Liver Fructose-1,6-bisphosphatase
Descriptor: 1-ETHYL-PYRROLIDINE-2,5-DIONE, 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, ...
Authors:Gao, Y, Honzatko, R.B.
Deposit date:2012-09-16
Release date:2013-09-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Fluorescent 2',3'-O-(2,4,6-trinitrophenyl) (TNP)-AMP Is an Active Site Inhibitor for Porcine Liver Fructose-1,6-bisphosphatase Rather Than Allosteric Inhibitor
To be Published
4KXP
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Crystal Structure of AMP complexes of Porcine Liver Fructose-1,6-bisphosphatase Mutant I10D in T-state
Descriptor: 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase 1, ...
Authors:Iancu, C.V, Mukund, S, Choe, J.-Y, Fromm, H.J, Honzatko, R.B.
Deposit date:2013-05-27
Release date:2013-07-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mechanism of Displacement of a Catalytically Essential Loop from the Active Site of Mammalian Fructose-1,6-bisphosphatase.
Biochemistry, 52, 2013

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