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1WNJ
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BU of 1wnj by Molmil
NMR structure of human coactosin-like protein
Descriptor: Coactosin-like protein
Authors:Liepinsh, E, Rakonjac, M, Boissonneault, V, Provost, P, Samuelsson, B, Radmark, O, Otting, G.
Deposit date:2004-08-05
Release date:2004-08-17
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:NMR structure of human coactosin-like protein
J.Biomol.Nmr, 30, 2004
1X67
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BU of 1x67 by Molmil
Solution structure of the cofilin homology domain of HIP-55 (drebrin-like protein)
Descriptor: Drebrin-like protein
Authors:Goroncy, A.K, Kigawa, T, Koshiba, S, Sato, M, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-17
Release date:2005-11-17
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:NMR solution structures of actin depolymerizing factor homology domains.
Protein Sci., 18, 2009
5L6W
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BU of 5l6w by Molmil
Structure Of the LIMK1-ATPgammaS-CFL1 Complex
Descriptor: Cofilin-1, LIM domain kinase 1, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
Authors:Salah, E, Mathea, S, Oerum, S, Newman, J.A, Tallant, C, Adamson, R, Canning, P, Beltrami, A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Bullock, A.N.
Deposit date:2016-05-31
Release date:2016-06-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Structure Of the LIMK1-ATPgammaS-CFL1 Complex
To Be Published
5HVK
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BU of 5hvk by Molmil
Crystal structure of LIMK1 mutant D460N in complex with full-length cofilin-1
Descriptor: Cofilin-1, LIM domain kinase 1, MAGNESIUM ION, ...
Authors:Hamill, S, Boggon, T.J.
Deposit date:2016-01-28
Release date:2016-05-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural Basis for Noncanonical Substrate Recognition of Cofilin/ADF Proteins by LIM Kinases.
Mol.Cell, 62, 2016
5Y1Z
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BU of 5y1z by Molmil
Crystal structure of ZMYND8 PHD-BROMO-PWWP tandem in complex with Drebrin ADF-H domain
Descriptor: Drebrin, GLYCEROL, Protein kinase C-binding protein 1, ...
Authors:Yao, N, Li, J, Liu, H, Wan, J, Liu, W, Zhang, M.
Deposit date:2017-07-22
Release date:2017-10-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.676 Å)
Cite:The Structure of the ZMYND8/Drebrin Complex Suggests a Cytoplasmic Sequestering Mechanism of ZMYND8 by Drebrin
Structure, 25, 2017
6YP9
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BU of 6yp9 by Molmil
Rabbit muscle actin in complex with ADF-H and ATP-ATTO-488
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Kogan, K, Kotila, T, Lappalainen, P.
Deposit date:2020-04-15
Release date:2020-12-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.564 Å)
Cite:A functional family of fluorescent nucleotide analogues to investigate actin dynamics and energetics.
Nat Commun, 12, 2021
6RSW
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BU of 6rsw by Molmil
HFD domain of mouse CAP1 bound to the pointed end of G-actin
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, Actin, ...
Authors:Kotila, T, Kogan, K, Lappalainen, P.
Deposit date:2019-05-22
Release date:2019-11-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Mechanism of synergistic actin filament pointed end depolymerization by cyclase-associated protein and cofilin.
Nat Commun, 10, 2019
8OH4
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BU of 8oh4 by Molmil
Subtomogram averaging structure of cofilactin filament inside microtubule lumen of Drosophila S2 cell protrusion.
Descriptor: Actin-5C, Cofilin/actin-depolymerizing factor homolog
Authors:Ventura Santos, C, Carter, A.P.
Deposit date:2023-03-20
Release date:2023-05-10
Method:ELECTRON MICROSCOPY (16.5 Å)
Cite:CryoET shows cofilactin filaments inside the microtubule lumen.
Biorxiv, 2023
7CCC
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BU of 7ccc by Molmil
The structure of the actin filament uncapping complex mediated by twinfilin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Robinson, R.C, Mwangangi, D.M.
Deposit date:2020-06-16
Release date:2021-02-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The structure of the actin filament uncapping complex mediated by twinfilin.
Sci Adv, 7, 2021
3DAW
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BU of 3daw by Molmil
Structure of the actin-depolymerizing factor homology domain in complex with actin
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Paavilainen, V.O, Oksanen, E, Goldman, A, Lappalainen, P.
Deposit date:2008-05-30
Release date:2008-07-29
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structure of the actin-depolymerizing factor homology domain in complex with actin
J.Cell Biol., 182, 2008
7Q8S
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BU of 7q8s by Molmil
Leishmania major ADP-actin filament decorated with Leishmania major cofilin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADF/Cofilin, Actin, ...
Authors:Kotila, T, Muniyandi, S, Lappalainen, P, Huiskonen, J.T.
Deposit date:2021-11-11
Release date:2022-05-18
Last modified:2022-06-29
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasite.
Nat Commun, 13, 2022
7U8K
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BU of 7u8k by Molmil
Magic Angle Spinning NMR Structure of Human Cofilin-2 Assembled on Actin Filaments
Descriptor: Actin, alpha skeletal muscle, Cofilin-2
Authors:Kraus, J, Russell, R, Kudryashova, E, Xu, C, Katyal, N, Kudryashov, D, Perilla, J.R, Polenova, T.
Deposit date:2022-03-08
Release date:2023-08-16
Last modified:2024-02-28
Method:SOLID-STATE NMR
Cite:Magic angle spinning NMR structure of human cofilin-2 assembled on actin filaments reveals isoform-specific conformation and binding mode.
Nat Commun, 13, 2022
3J0S
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BU of 3j0s by Molmil
Remodeling of actin filaments by ADF cofilin proteins
Descriptor: Actin, cytoplasmic 1, Cofilin-2
Authors:Galkin, V.E, Orlova, A, Kudryashov, D.S, Solodukhin, A, Reisler, E, Schroeder, G.F, Egelman, E.H.
Deposit date:2011-11-24
Release date:2011-12-21
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Remodeling of actin filaments by ADF/cofilin proteins.
Proc.Natl.Acad.Sci.USA, 108, 2011
5YU8
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BU of 5yu8 by Molmil
Cofilin decorated actin filament
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Tanaka, K, Narita, A.
Deposit date:2017-11-21
Release date:2018-05-23
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis for cofilin binding and actin filament disassembly
Nat Commun, 9, 2018
4JD2
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BU of 4jd2 by Molmil
Crystal structure of Bos taurus Arp2/3 complex binding with Mus musculus GMF
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, ...
Authors:Nolen, B.J, Luan, Q.
Deposit date:2013-02-22
Release date:2013-07-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.08 Å)
Cite:Structural basis for regulation of Arp2/3 complex by GMF.
Nat.Struct.Mol.Biol., 20, 2013
6UC4
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BU of 6uc4 by Molmil
Barbed end side of a cofilactin cluster
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Huehn, A.R, Bibeau, J.P, Schramm, A.C, Cao, W, De La Cruz, E.M, Sindelar, C.V.
Deposit date:2019-09-13
Release date:2020-01-01
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (9.2 Å)
Cite:Structures of cofilin-induced structural changes reveal local and asymmetric perturbations of actin filaments.
Proc.Natl.Acad.Sci.USA, 117, 2020
6UC0
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BU of 6uc0 by Molmil
Isolated S3D-cofilin bound to an actin filament
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Huehn, A.R, Bibeau, J.P, Schramm, A.C, Cao, W, De La Cruz, E.M, Sindelar, C.V.
Deposit date:2019-09-13
Release date:2020-01-01
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Structures of cofilin-induced structural changes reveal local and asymmetric perturbations of actin filaments.
Proc.Natl.Acad.Sci.USA, 117, 2020
6UBY
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BU of 6uby by Molmil
Isolated cofilin bound to an actin filament
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Huehn, A.R, Bibeau, J.P, Schramm, A.C, Cao, W, De La Cruz, E.M, Sindelar, C.V.
Deposit date:2019-09-13
Release date:2020-01-01
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Structures of cofilin-induced structural changes reveal local and asymmetric perturbations of actin filaments.
Proc.Natl.Acad.Sci.USA, 117, 2020
6VAO
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BU of 6vao by Molmil
Human cofilin-1 decorated actin filament
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Huehn, A.R, Bibeau, J.P, Schramm, A.C, Cao, W, De La Cruz, E.M, Sindelar, C.V.
Deposit date:2019-12-17
Release date:2020-01-08
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of cofilin-induced structural changes reveal local and asymmetric perturbations of actin filaments.
Proc.Natl.Acad.Sci.USA, 117, 2020
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