PDB: 67 resultsInfo pagesStatus searchChemie searchBIRD

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3DTB	The structure of rat cytosolic PEPCK in complex with phosphoglycolate and GDP Descriptor: 2-PHOSPHOGLYCOLIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BICARBONATE ION, ... Authors: Sullivan, S.M, Holyoak, T. Deposit date: 2008-07-14 Release date: 2008-08-26 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selection. Proc.Natl.Acad.Sci.Usa, 105, 2008
4YW8	Structure of rat cytosolic pepck in complex with 3-mercaptopicolinic acid Descriptor: 1,2-ETHANEDIOL, 3-sulfanylpyridine-2-carboxylic acid, MANGANESE (II) ION, ... Authors: Balan, M.D, Johnson, T.A, Mcleod, M.J, Lotosky, W.R, Holyoak, T. Deposit date: 2015-03-20 Release date: 2015-09-23 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Inhibition and Allosteric Regulation of Monomeric Phosphoenolpyruvate Carboxykinase by 3-Mercaptopicolinic Acid. Biochemistry, 54, 2015
4YWB	Structure of rat cytosolic pepck in complex with 3-mercaptopicolinic acid and oxalic acid Descriptor: 3-sulfanylpyridine-2-carboxylic acid, CHLORIDE ION, MANGANESE (II) ION, ... Authors: Balan, M.D, Johnson, T.A, Lotosky, W.R, Mcleod, M.J, Holyoak, T. Deposit date: 2015-03-20 Release date: 2015-09-23 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Inhibition and Allosteric Regulation of Monomeric Phosphoenolpyruvate Carboxykinase by 3-Mercaptopicolinic Acid. Biochemistry, 54, 2015
1KHE	PEPCK complex with nonhydrolyzable GTP analog, MAD data Descriptor: MANGANESE (II) ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Phosphoenolpyruvate Carboxykinase, ... Authors: Dunten, P, Belunis, C, Crowther, R, Hollfelder, K, Kammlott, U, Levin, W, Michel, H, Ramsey, G.B, Swain, A, Weber, D, Wertheimer, S.J. Deposit date: 2001-11-29 Release date: 2002-02-27 Last modified: 2017-10-11 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site. J.Mol.Biol., 316, 2002
1KHB	PEPCK complex with nonhydrolyzable GTP analog, native data Descriptor: 1,2-ETHANEDIOL, ACETATE ION, MANGANESE (II) ION, ... Authors: Dunten, P, Belunis, C, Crowther, R, Hollfelder, K, Kammlott, U, Levin, W, Michel, H, Ramsey, G.B, Swain, A, Weber, D, Wertheimer, S.J. Deposit date: 2001-11-29 Release date: 2002-02-27 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.854 Å) Cite: Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site. J.Mol.Biol., 316, 2002
1KHF	PEPCK complex with PEP Descriptor: 1,2-ETHANEDIOL, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, ... Authors: Dunten, P, Belunis, C, Crowther, R, Hollfelder, K, Kammlott, U, Levin, W, Michel, H, Ramsey, G.B, Swain, A, Weber, D, Wertheimer, S.J. Deposit date: 2001-11-29 Release date: 2002-02-27 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site. J.Mol.Biol., 316, 2002
3DT2	The structure of rat cytosolic PEPCK in complex with oxalate and GTP Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, OXALATE ION, ... Authors: Sullivan, S.M, Holyoak, T. Deposit date: 2008-07-14 Release date: 2008-08-26 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selection. Proc.Natl.Acad.Sci.Usa, 105, 2008
3DT7	The structure of rat cytosolic PEPCK in complex with beta-sulfopyruvate and GTP Descriptor: 2-ETHOXYETHANOL, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... Authors: Sullivan, S.M, Holyoak, T. Deposit date: 2008-07-14 Release date: 2008-08-26 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selection. Proc.Natl.Acad.Sci.Usa, 105, 2008
4YWD	Structure of rat cytosolic pepck in complex with 2,3-Pyridine dicarboxylic acid Descriptor: MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, cytosolic [GTP], ... Authors: Balan, M.D, Johnson, T.A, Mcleod, M.J, Lotosky, W.R, Holyoak, T. Deposit date: 2015-03-20 Release date: 2015-09-23 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Inhibition and Allosteric Regulation of Monomeric Phosphoenolpyruvate Carboxykinase by 3-Mercaptopicolinic Acid. Biochemistry, 54, 2015
3DT4	The structure of rat cytosolic PEPCK in complex with oxalate and GTP Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, OXALATE ION, ... Authors: Sullivan, S.M, Holyoak, T. Deposit date: 2008-07-14 Release date: 2008-08-26 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selection. Proc.Natl.Acad.Sci.Usa, 105, 2008
1KHG	PEPCK Descriptor: 1,2-ETHANEDIOL, MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, ... Authors: Dunten, P, Belunis, C, Crowther, R, Hollfelder, K, Kammlott, U, Levin, W, Michel, H, Ramsey, G.B, Swain, A, Weber, D, Wertheimer, S.J. Deposit date: 2001-11-29 Release date: 2002-02-27 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.34 Å) Cite: Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site. J.Mol.Biol., 316, 2002
5V9H	Structure of the H477R variant of rat cytosolic PEPCK in complex with phosphoglycolate and GDP. Descriptor: 2-PHOSPHOGLYCOLIC ACID, GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... Authors: Holyoak, T, Cui, D.S. Deposit date: 2017-03-23 Release date: 2017-04-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Asymmetric Anchoring Is Required for Efficient Omega-Loop Opening and Closing in Cytosolic Phosphoenolpyruvate Carboxykinase. Biochemistry, 56, 2017
5V9F	Structure of the H477R variant of rat cytosolic PEPCK in complex with beta sulfopyruvate and GTP. Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, ... Authors: Holyoak, T, Cui, D.S. Deposit date: 2017-03-23 Release date: 2017-04-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Asymmetric Anchoring Is Required for Efficient Omega-Loop Opening and Closing in Cytosolic Phosphoenolpyruvate Carboxykinase. Biochemistry, 56, 2017
5V9G	Structure of the H477R variant of rat cytosolic PEPCK in complex with oxalate and GTP. Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, OXALATE ION, ... Authors: Holyoak, T, Cui, D.S. Deposit date: 2017-03-23 Release date: 2017-04-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Asymmetric Anchoring Is Required for Efficient Omega-Loop Opening and Closing in Cytosolic Phosphoenolpyruvate Carboxykinase. Biochemistry, 56, 2017
5V95	Structure of the H477R variant of rat cytosolic PEPCK in complex with manganese. Descriptor: MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, cytosolic [GTP], ... Authors: Holyoak, T, Cui, D.S. Deposit date: 2017-03-23 Release date: 2017-04-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Asymmetric Anchoring Is Required for Efficient Omega-Loop Opening and Closing in Cytosolic Phosphoenolpyruvate Carboxykinase. Biochemistry, 56, 2017
5V97	Structure of the H477R variant of rat cytosolic PEPCK in complex with GTP. Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, ... Authors: Holyoak, T, Cui, D.S. Deposit date: 2017-03-23 Release date: 2017-04-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Asymmetric Anchoring Is Required for Efficient Omega-Loop Opening and Closing in Cytosolic Phosphoenolpyruvate Carboxykinase. Biochemistry, 56, 2017
4WIE	Crystal structure of apo-PEPCK from Mycobacterium tuberculosis with glycerol Descriptor: GLYCEROL, MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase [GTP] Authors: Kim, H.L, Sacchettini, J.C. Deposit date: 2014-09-25 Release date: 2014-10-22 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.18 Å) Cite: Crystal structure of apo-PEPCK from Mycobacterium tuberculosis with glycerol To Be Published
4WIU	Crystal Structure of PEPCK (Rv0211) from Mycobacterium tuberculosis in complex with oxalate and Mn2+ Descriptor: GLYCEROL, MANGANESE (II) ION, OXALATE ION, ... Authors: Kim, H.L, Sacchettini, J.C. Deposit date: 2014-09-26 Release date: 2014-10-22 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Crystal Structure of PEPCK (Rv0211) from Mycobacterium tuberculosis in complex with oxalate and Mn2+ to be published
4WPV	Crystal Structure of E83A mutant of Mtb PEPCK in complex with Zn2+ and phosphate ion Descriptor: GLYCEROL, PHOSPHATE ION, Phosphoenolpyruvate carboxykinase [GTP], ... Authors: Kim, H.L, Sacchettini, J.C. Deposit date: 2014-10-21 Release date: 2015-11-04 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.672 Å) Cite: Crystal Structure of E83A from Mtb PEPCK in complex with Zn2+ and phosphate ion To Be Published
4WPT	Crystal Structure of Mtb PEPCK in complex with PEP Descriptor: GLYCEROL, PHOSPHATE ION, PHOSPHOENOLPYRUVATE, ... Authors: Kim, H.L, Krieger, I.V, Sacchettini, J.C. Deposit date: 2014-10-21 Release date: 2015-11-04 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal Structure of Mtb PEPCK in complex with PEP To Be Published
4WPU	Crystal Structure of E83A mutant of Mtb PEPCK in complex with PEP and GDP Descriptor: GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, PHOSPHOENOLPYRUVATE, ... Authors: Kim, H.L, Sacchettini, J.C. Deposit date: 2014-10-21 Release date: 2015-11-04 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.26 Å) Cite: Crystal Structure of E83A mutant of Mtb PEPCK in complex with PEP and GDP To Be Published
4WL8	Crystal Structure of Mtb PEPCK in complex with non-hydrolyzable analog of GTP Descriptor: GLYCEROL, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... Authors: Kim, H.L, Sacchettini, J.C. Deposit date: 2014-10-06 Release date: 2015-10-21 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.61 Å) Cite: Crystal Structure of Mtb PEPCK in complex with non-hydrolyzable analog of GTP to be published
4WOU	Crystal Structure of Mtb PEPCK in complex with GDP and metals Descriptor: GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... Authors: Kim, H.L, Sacchettini, J.C. Deposit date: 2014-10-16 Release date: 2015-11-04 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.122 Å) Cite: Crystal Structure of Mtb PEPCK in complex with GDP and metals To Be Published
4GMZ	Structure of rat cytosolic PEPCK Ld_2g in complex with Beta-Sulfopyruvate and GTP Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, ... Authors: Johnson, T.A, Holyoak, T. Deposit date: 2012-08-16 Release date: 2013-07-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.05 Å) Cite: The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function. Biochemistry, 51, 2012
4GMM	Structure of rat cytosolic PEPCK Ld_1g in complex with Beta-Sulfopyruvate and GTP Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, ... Authors: Johnson, T.A, Holyoak, T. Deposit date: 2012-08-16 Release date: 2013-07-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.736 Å) Cite: The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function. Biochemistry, 51, 2012

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