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6J7I
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BU of 6j7i by Molmil
Fusion protein of heme oxygenase-1 and NADPH cytochrome P450 reductase (15aa)
Descriptor: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, Heme oxygenase 1,NADPH--cytochrome P450 reductase, ...
Authors:Sugishima, M, Sato, H, Wada, K, Yamamoto, K.
Deposit date:2019-01-18
Release date:2019-04-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal structure of a NADPH-cytochrome P450 oxidoreductase (CYPOR) and heme oxygenase 1 fusion protein implies a conformational change in CYPOR upon NADPH/NADP+binding.
Febs Lett., 593, 2019
7SUX
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BU of 7sux by Molmil
NADPH-dependent cytochrome P450 reductase 2b from Sorghum bicolor (SbCPR2b) -NADP+ complex
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADPH--cytochrome P450 reductase
Authors:Zhang, B, Kang, C.
Deposit date:2021-11-18
Release date:2022-08-31
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Functional and structural insight into the flexibility of cytochrome P450 reductases from Sorghum bicolor and its implications for lignin composition.
J.Biol.Chem., 298, 2022
7SV0
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BU of 7sv0 by Molmil
NADPH-dependent cytochrome P450 reductase 2b from Sorghum bicolor (SbCPR2b) -oxidized form of NADP+ complex
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADPH--cytochrome P450 reductase
Authors:Zhang, B, Kang, C.
Deposit date:2021-11-18
Release date:2022-08-31
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Functional and structural insight into the flexibility of cytochrome P450 reductases from Sorghum bicolor and its implications for lignin composition.
J.Biol.Chem., 298, 2022
7SUZ
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BU of 7suz by Molmil
NADPH-dependent cytochrome P450 reductase 2b from Sorghum bicolor (SbCPR2b)
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, NADPH--cytochrome P450 reductase
Authors:Zhang, B, Kang, C.
Deposit date:2021-11-18
Release date:2022-08-31
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Functional and structural insight into the flexibility of cytochrome P450 reductases from Sorghum bicolor and its implications for lignin composition.
J.Biol.Chem., 298, 2022
2BPO
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BU of 2bpo by Molmil
Crystal structure of the yeast CPR triple mutant: D74G, Y75F, K78A.
Descriptor: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Yermalitskaya, L.V, Kim, Y, Waterman, M.R, Podust, L.M.
Deposit date:2005-04-21
Release date:2006-07-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structure of the Yeast Cpr Triple Mutant: D74G, Y75F, K78A.
To be Published
2BF4
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BU of 2bf4 by Molmil
A second FMN-binding site in yeast NADPH-cytochrome P450 reductase suggests a novel mechanism of electron transfer by diflavin reductases.
Descriptor: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Podust, L.M, Lepesheva, G.I, Kim, Y, Yermalitskaya, L.V, Yermalitsky, V.N, Lamb, D.C, Kelly, S.L, Waterman, M.R.
Deposit date:2004-12-03
Release date:2006-01-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:A Second Fmn-Binding Site in Yeast Nadph-Cytochrome P450 Reductase Suggests a Mechanism of Electron Transfer by Diflavin Reductases.
Structure, 14, 2006
1JA0
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BU of 1ja0 by Molmil
CYPOR-W677X
Descriptor: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Hubbard, P.A, Shen, A.L, Paschke, R, Kasper, C.B, Kim, J.J.
Deposit date:2001-05-29
Release date:2001-08-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:NADPH-cytochrome P450 oxidoreductase. Structural basis for hydride and electron transfer.
J.Biol.Chem., 276, 2001
1J9Z
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BU of 1j9z by Molmil
CYPOR-W677G
Descriptor: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Hubbard, P.A, Shen, A.L, Paschke, R, Kasper, C.B, Kim, J.J.
Deposit date:2001-05-29
Release date:2001-08-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:NADPH-cytochrome P450 oxidoreductase. Structural basis for hydride and electron transfer.
J.Biol.Chem., 276, 2001
1JA1
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BU of 1ja1 by Molmil
CYPOR-Triple Mutant
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Hubbard, P.A, Shen, A.L, Paschke, R, Kasper, C.B, Kim, J.J.
Deposit date:2001-05-29
Release date:2001-08-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:NADPH-cytochrome P450 oxidoreductase. Structural basis for hydride and electron transfer.
J.Biol.Chem., 276, 2001
2BN4
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BU of 2bn4 by Molmil
A second FMN-binding site in yeast NADPH-cytochrome P450 reductase suggests a novel mechanism of electron transfer by diflavin reductase
Descriptor: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Podust, L.M, Lepesheva, G.I, Kim, Y, Yermalitskaya, L.V, Yermalitsky, V.N, Lamb, D.C, Kelly, S.L, Waterman, M.R.
Deposit date:2005-03-18
Release date:2006-01-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:A Second Fmn-Binding Site in Yeast Nadph-Cytochrome P450 Reductase Suggests a Mechanism of Electron Transfer by Diflavin Reductases.
Structure, 14, 2006
6J7A
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BU of 6j7a by Molmil
Fusion protein of heme oxygenase-1 and NADPH cytochrome P450 reductase (17aa)
Descriptor: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, Heme oxygenase 1,NADPH--cytochrome P450 reductase, ...
Authors:Sugishima, M, Sato, H, Wada, K, Yamamoto, K.
Deposit date:2019-01-17
Release date:2019-04-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.269 Å)
Cite:Crystal structure of a NADPH-cytochrome P450 oxidoreductase (CYPOR) and heme oxygenase 1 fusion protein implies a conformational change in CYPOR upon NADPH/NADP+binding.
Febs Lett., 593, 2019
1F20
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BU of 1f20 by Molmil
CRYSTAL STRUCTURE OF RAT NEURONAL NITRIC-OXIDE SYNTHASE FAD/NADP+ DOMAIN AT 1.9A RESOLUTION.
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, FORMIC ACID, GLYCEROL, ...
Authors:Zhang, J, Martasek, P, Masters, B.S, Kim, J.P.
Deposit date:2000-05-22
Release date:2001-10-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the FAD/NADPH-binding domain of rat neuronal nitric-oxide synthase. Comparisons with NADPH-cytochrome P450 oxidoreductase.
J.Biol.Chem., 276, 2001
5URD
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BU of 5urd by Molmil
wild type rat CYPOR bound with NADP+ - oxidized form
Descriptor: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Xia, C, Kim, J.J.
Deposit date:2017-02-10
Release date:2018-02-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer.
Biochemistry, 57, 2018
5URH
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BU of 5urh by Molmil
CYPOR/D632A with NADP+
Descriptor: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Xia, C, Kim, J.J.
Deposit date:2017-02-10
Release date:2018-02-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer.
Biochemistry, 57, 2018
5URE
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BU of 5ure by Molmil
Wild type rat CYPOR bound with NADP+ - reduced form
Descriptor: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Xia, C, Kim, J.J.
Deposit date:2017-02-10
Release date:2018-02-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer.
Biochemistry, 57, 2018
5URG
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BU of 5urg by Molmil
rat CYPOR D632F mutant
Descriptor: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Xia, C, Kim, J.J.
Deposit date:2017-02-10
Release date:2018-02-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer.
Biochemistry, 57, 2018
5URI
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BU of 5uri by Molmil
Rat CYPOR/D632A with 2'-AMP
Descriptor: ADENOSINE-2'-MONOPHOSPHATE, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Xia, C, Kim, J.J.
Deposit date:2017-02-10
Release date:2018-02-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer.
Biochemistry, 57, 2018
4YAU
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BU of 4yau by Molmil
Reduced CYPOR mutant - G141del/E142N
Descriptor: ADENOSINE-2'-MONOPHOSPHATE, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Xia, C, Kim, J.J.P.
Deposit date:2015-02-17
Release date:2016-03-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
J.Biol.Chem., 291, 2016
4Y9U
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BU of 4y9u by Molmil
rat CYPOR mutant - G143del
Descriptor: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Xia, C, Kim, J.J.P.
Deposit date:2015-02-17
Release date:2016-03-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
J.Biol.Chem., 291, 2016
3OJW
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BU of 3ojw by Molmil
Disulfide crosslinked cytochrome P450 reductase inactive
Descriptor: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADPH-cytochrome P450 reductase
Authors:Xia, C, Hamdane, D, Shen, A, Choi, V, Kasper, C, Zhang, H, Im, S.-C, Waskell, L, Kim, J.-J.P.
Deposit date:2010-08-23
Release date:2011-02-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Conformational Changes of NADPH-Cytochrome P450 Oxidoreductase Are Essential for Catalysis and Cofactor Binding.
J.Biol.Chem., 286, 2011
4Y9R
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BU of 4y9r by Molmil
rat CYPOR mutant - G141del
Descriptor: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Xia, C, Kim, J.J.P.
Deposit date:2015-02-17
Release date:2016-03-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
J.Biol.Chem., 291, 2016
4YAL
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BU of 4yal by Molmil
Reduced CYPOR with 2'-AMP
Descriptor: ADENOSINE-2'-MONOPHOSPHATE, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Xia, C, Kim, J.J.P.
Deposit date:2015-02-17
Release date:2016-03-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
J.Biol.Chem., 291, 2016
4YAO
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BU of 4yao by Molmil
Reduced CYPOR mutant - G143del
Descriptor: ADENOSINE-2'-MONOPHOSPHATE, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Xia, C, Kim, J.J.P.
Deposit date:2015-02-17
Release date:2016-03-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
J.Biol.Chem., 291, 2016
3OJX
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BU of 3ojx by Molmil
Disulfide crosslinked cytochrome P450 reductase inactive
Descriptor: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Xia, C, Hamdane, D, Shen, A, Choi, V, Kasper, C, Zhang, H, Im, S.-C, Waskell, L, Kim, J.-J.P.
Deposit date:2010-08-23
Release date:2011-02-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Conformational Changes of NADPH-Cytochrome P450 Oxidoreductase Are Essential for Catalysis and Cofactor Binding.
J.Biol.Chem., 286, 2011
3QFR
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BU of 3qfr by Molmil
Crystal Structure of Human NADPH-Cytochrome P450 Reductase (R457H Mutant)
Descriptor: CALCIUM ION, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Xia, C, Marohnic, C, Panda, S.P, Masters, B.S, Kim, J.-J.P.
Deposit date:2011-01-22
Release date:2011-08-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for human NADPH-cytochrome P450 oxidoreductase deficiency.
Proc.Natl.Acad.Sci.USA, 108, 2011

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