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6TPT
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Crystal structures of FNIII domain three and four of the human leucocyte common antigen-related protein, LAR
Descriptor: Receptor-type tyrosine-protein phosphatase F
Authors:Vilstrup, J.P, Thirup, S.S, Simonsen, A, Birkefeldt, T, Strandbygaard, D.
Deposit date:2019-12-14
Release date:2020-05-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal and solution structures of fragments of the human leucocyte common antigen-related protein.
Acta Crystallogr D Struct Biol, 76, 2020
6TPV
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BU of 6tpv by Molmil
Crystal structures of FNIII domain one and two of the human leucocyte common antigen-related protein, LAR
Descriptor: IMIDAZOLE, Receptor-type tyrosine-protein phosphatase F
Authors:Vilstrup, J.P, Thirup, S.S, Simonsen, A, Birkefeldt, T, Strandbygaard, D.
Deposit date:2019-12-14
Release date:2020-05-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal and solution structures of fragments of the human leucocyte common antigen-related protein.
Acta Crystallogr D Struct Biol, 76, 2020
6XAX
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Structure of a fragment of human fibronectin containing the 11th type III domain, extra domain A, and the 12th type III domain
Descriptor: Fibronectin, GLYCEROL
Authors:Mou, T.C, Nepomuceno, P.A, Sprang, S.R, Briknarova, K.
Deposit date:2020-06-04
Release date:2021-06-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Fragment of human fibronectin containing the 11th type III domain, extra domain A, and 12th type III domain
To Be Published
6XAY
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Structure of a fragment of human fibronectin containing the 10th, 11th and 12th type III domains
Descriptor: Fibronectin, GLYCEROL
Authors:Mou, T.C, Nepomuceno, P.A, Sprang, S.R, Briknarova, K.
Deposit date:2020-06-05
Release date:2021-06-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Fragment of human fibronectin containing the 10th, 11th and 12th type III domains
To Be Published
7JGT
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Crystal Structure of FN3tt
Descriptor: Fibronectin type-III domain-containing protein
Authors:Luo, J, Malia, T.J.
Deposit date:2020-07-19
Release date:2021-07-21
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Surface salt bridges contribute to the extreme thermal stability of an FN3-like domain from a thermophilic bacterium.
Proteins, 90, 2022
7JGU
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Structure of FN3tt mut
Descriptor: Fibronectin type-III domain-containing protein, PENTAETHYLENE GLYCOL
Authors:Luo, J, Boucher, L.E.
Deposit date:2020-07-19
Release date:2021-07-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Surface salt bridges contribute to the extreme thermal stability of an FN3-like domain from a thermophilic bacterium.
Proteins, 90, 2022
1OWW
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Solution structure of the first type III module of human fibronectin determined by 1H, 15N NMR spectroscopy
Descriptor: Fibronectin first type III module
Authors:Gao, M, Craig, D, Lequin, O, Campbell, I.D, Vogel, V, Schulten, K.
Deposit date:2003-03-31
Release date:2003-10-07
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure and functional significance of mechanically unfolded fibronectin type III1 intermediates
Proc.Natl.Acad.Sci.USA, 100, 2003
6TPW
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Crystal structures of FNIII domain one through four of the human leucocyte common antigen-related protein ( LAR)
Descriptor: Receptor-type tyrosine-protein phosphatase F, SULFATE ION
Authors:Vilstrup, J.P, Thirup, S.S, Simonsen, A, Birkefeldt, T, Strandbygaard, D.
Deposit date:2019-12-14
Release date:2020-05-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal and solution structures of fragments of the human leucocyte common antigen-related protein.
Acta Crystallogr D Struct Biol, 76, 2020
5N06
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BU of 5n06 by Molmil
Crystal structure of Tie1 Fibronectin-like domain 3
Descriptor: Tyrosine-protein kinase receptor Tie-1
Authors:Leppanen, V.-M, Saharinen, P, Alitalo, K.
Deposit date:2017-02-02
Release date:2017-04-26
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Structural basis of Tie2 activation and Tie2/Tie1 heterodimerization.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1BJ8
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THIRD N-TERMINAL DOMAIN OF GP130, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: GP130
Authors:Kernebeck, T, Pflanz, S, Muller-Newen, G, Kurapkat, G, Scheek, R.M, Dijkstra, K, Heinrich, P.C, Wollmer, A, Grzesiek, S, Grotzinger, J.
Deposit date:1998-07-02
Release date:1999-01-13
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The signal transducer gp130: solution structure of the carboxy-terminal domain of the cytokine receptor homology region.
Protein Sci., 8, 1999
7E72
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Crystal structure of Tie2-agonistic antibody in complex with human Tie2 Fn2-3
Descriptor: 1,2-ETHANEDIOL, Angiopoietin-1 receptor, the chimeric Fab fragment of 3H7 (heavy chain), ...
Authors:Kim, H.M, Jo, G.H, Hong, H.J, Han, A.
Deposit date:2021-02-25
Release date:2021-11-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.094 Å)
Cite:Structural insights into the clustering and activation of Tie2 receptor mediated by Tie2 agonistic antibody.
Nat Commun, 12, 2021
1Q38
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Anastellin
Descriptor: Fibronectin
Authors:Briknarova, K, Akerman, M.E, Hoyt, D.W, Ruoslahti, E, Ely, K.R.
Deposit date:2003-07-28
Release date:2003-11-04
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Anastellin, an FN3 fragment with fibronectin polymerization activity, resembles amyloid fibril precursors
J.Mol.Biol., 332, 2003
5FM8
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Structure of the C-terminally extended domain My4 of human myomesin (space group P65)
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MYOMESIN-1, NICKEL (II) ION
Authors:Pernigo, S, Steiner, R.A.
Deposit date:2015-11-02
Release date:2016-11-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Binding of Myomesin to Obscurin-Like-1 at the Muscle M-Band Provides a Strategy for Isoform-Specific Mechanical Protection.
Structure, 25, 2017
3L5I
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BU of 3l5i by Molmil
Crystal structure of FnIII domains of human GP130 (Domains 4-6)
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Interleukin-6 receptor subunit beta
Authors:Kershaw, N.J, Zhang, J.-G, Garrett, T.P.J, Czabotar, P.E.
Deposit date:2009-12-22
Release date:2010-05-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the entire ectodomain of gp130: insights into the molecular assembly of the tall cytokine receptor complexes.
J.Biol.Chem., 285, 2010
2MNU
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Backbone and side chain 1H, 13C, and 15N Chemical Shift Assignments for EDB and specific binding aptide
Descriptor: APT, EDB
Authors:Suh, J, Yu, T.
Deposit date:2014-04-10
Release date:2014-09-24
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:An Unusual Protein-Protein Interaction through Coupled Unfolding and Binding
Angew.Chem.Int.Ed.Engl., 53, 2014
1J8K
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BU of 1j8k by Molmil
NMR STRUCTURE OF THE FIBRONECTIN EDA DOMAIN, NMR, 20 STRUCTURES
Descriptor: FIBRONECTIN
Authors:Niimi, T, Osawa, M, Yamaji, N, Yasunaga, K, Sakashita, H, Mase, T, Tanaka, A, Fujita, S.
Deposit date:2001-05-22
Release date:2002-02-06
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:NMR structure of human fibronectin EDA.
J.Biomol.NMR, 21, 2001
3L5J
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Crystal structure of FnIII domains of human GP130 (Domains 4-6)
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Interleukin-6 receptor subunit beta
Authors:Kershaw, N.J, Zhang, J.-G, Garrett, T.P.J, Czabotar, P.E.
Deposit date:2009-12-22
Release date:2010-05-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.042 Å)
Cite:Crystal structure of the entire ectodomain of gp130: insights into the molecular assembly of the tall cytokine receptor complexes.
J.Biol.Chem., 285, 2010
6GVL
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BU of 6gvl by Molmil
Second pair of Fibronectin type III domains of integrin beta4 bound to the bullous pemphigoid antigen BP230 (BPAG1e)
Descriptor: Dystonin, Integrin beta-4
Authors:Manso, J.A, Gomez-Hernandez, M, Alonso-Garcia, N, de Pereda, J.M.
Deposit date:2018-06-21
Release date:2019-03-20
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Integrin alpha 6 beta 4 Recognition of a Linear Motif of Bullous Pemphigoid Antigen BP230 Controls Its Recruitment to Hemidesmosomes.
Structure, 27, 2019
3LPW
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Crystal structure of the FnIII-tandem A77-A78 from the A-band of titin
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, A77-A78 domain from Titin
Authors:Bucher, R.M, Mayans, O.
Deposit date:2010-02-06
Release date:2010-09-08
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The structure of the FnIII Tandem A77-A78 points to a periodically conserved architecture in the myosin-binding region of titin
J.Mol.Biol., 401, 2010
2MFN
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SOLUTION NMR STRUCTURE OF LINKED CELL ATTACHMENT MODULES OF MOUSE FIBRONECTIN CONTAINING THE RGD AND SYNERGY REGIONS, 10 STRUCTURES
Descriptor: FIBRONECTIN
Authors:Copie, V, Tomita, Y, Akiyama, S.K, Aota, S, Yamada, K.M, Venable, R.M, Pastor, R.W, Krueger, S, Torchia, D.A.
Deposit date:1998-02-11
Release date:1998-04-29
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure and dynamics of linked cell attachment modules of mouse fibronectin containing the RGD and synergy regions: comparison with the human fibronectin crystal structure.
J.Mol.Biol., 277, 1998
8T9B
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BU of 8t9b by Molmil
Structure of the CK variant of Fab F1 (FabC-F1) in complex with the C-terminal FN3 domain of EphA2
Descriptor: CK variant of Fab F1 heavy chain, CK variant of Fab F1 light chain, Ephrin type-A receptor 2
Authors:Singer, A.U, Bruce, H.A, Enderle, L, Blazer, L, Adams, J.J, Sicheri, F, Sidhu, S.S.
Deposit date:2023-06-23
Release date:2024-05-01
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Engineered Antigen-binding Fragments for Enhanced Crystallization of Antibody:Antigen Complexes
To be Published
6GVK
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Second pair of Fibronectin type III domains of integrin beta4 (T1663R mutant) bound to the bullous pemphigoid antigen BP230 (BPAG1e)
Descriptor: Dystonin, GLYCEROL, Integrin beta-4
Authors:Manso, J.A, Gomez-Hernandez, M, Alonso-Garcia, N, de Pereda, J.M.
Deposit date:2018-06-21
Release date:2019-03-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Integrin alpha 6 beta 4 Recognition of a Linear Motif of Bullous Pemphigoid Antigen BP230 Controls Its Recruitment to Hemidesmosomes.
Structure, 27, 2019
2N1K
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Structure of the Third Type III Domain from Human Fibronectin
Descriptor: Fibronectin
Authors:Stine, J.M, Sun, Y, Armstrong, G, Briknarova, K.
Deposit date:2015-04-04
Release date:2015-11-11
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure and Unfolding of the Third Type III Domain from Human Fibronectin.
Biochemistry, 54, 2015
5FN8
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Crystal structure of rat CD45 extracellular region, domains d3-d4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRATE ANION, RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C
Authors:Chang, V.T, Fernandes, R.A, Ganzinger, K.A, Lee, S.F, Siebold, C, McColl, J, Jonsson, P, Palayret, M, Harlos, K, Coles, C.H, Jones, E.Y, Lui, Y, Huang, E, Gilbert, R.J.C, Klenerman, D, Aricescu, A.R, Davis, S.J.
Deposit date:2015-11-11
Release date:2016-03-23
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Initiation of T Cell Signaling by Cd45 Segregation at 'Close Contacts'.
Nat.Immunol., 17, 2016
6HYF
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Crystal structure of the third FNIII domain from rat beta4 integrin, a binding site for periaxin
Descriptor: Integrin beta-4
Authors:Raasakka, A, Kursula, P.
Deposit date:2018-10-20
Release date:2019-05-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Direct Binding of the Flexible C-Terminal Segment of Periaxin to beta 4 Integrin Suggests a Molecular Basis for CMT4F.
Front Mol Neurosci, 12, 2019

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