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6YBP
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BU of 6ybp by Molmil
Propionyl-CoA carboxylase of Methylorubrum extorquens with bound CoA
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Propionyl-CoA carboxylase alpha subunit, ...
Authors:Schuller, J.M, Schuller, S.K, Zarzycki, J, Scheffen, M, Marchal, D.M, Erb, T.J.
Deposit date:2020-03-17
Release date:2020-10-28
Last modified:2021-05-12
Method:ELECTRON MICROSCOPY (3.48 Å)
Cite:A new-to-nature carboxylation module to improve natural and synthetic CO2 fixation
Nat Catal, 2021
5MLK
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BU of 5mlk by Molmil
Biotin dependent carboxylase AccA3 dimer from Mycobacterium tuberculosis (Rv3285)
Descriptor: Acetyl-COA carboxylase
Authors:Bennett, M.D, Hogbom, M.
Deposit date:2016-12-07
Release date:2017-03-08
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.939 Å)
Cite:Crystal structure of the essential biotin-dependent carboxylase AccA3 from Mycobacterium tuberculosis.
FEBS Open Bio, 7, 2017
1BNC
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BU of 1bnc by Molmil
THREE-DIMENSIONAL STRUCTURE OF THE BIOTIN CARBOXYLASE SUBUNIT OF ACETYL-COA CARBOXYLASE
Descriptor: BIOTIN CARBOXYLASE, PHOSPHATE ION
Authors:Waldrop, G, Rayment, I, Holden, H.M.
Deposit date:1994-07-06
Release date:1995-08-30
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Three-dimensional structure of the biotin carboxylase subunit of acetyl-CoA carboxylase.
Biochemistry, 33, 1994
6YBQ
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BU of 6ybq by Molmil
Engineered glycolyl-CoA carboxylase (quintuple mutant) with bound CoA
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Propionyl-CoA carboxylase alpha subunit, ...
Authors:Schuller, J.M, Schuller, S.K, Zarzycki, J, Scheffen, M, Marchal, D.M, Erb, T.J.
Deposit date:2020-03-17
Release date:2020-10-28
Last modified:2021-05-12
Method:ELECTRON MICROSCOPY (1.96 Å)
Cite:A new-to-nature carboxylation module to improve natural and synthetic CO2 fixation
Nat Catal, 2021
1ULZ
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BU of 1ulz by Molmil
Crystal structure of the biotin carboxylase subunit of pyruvate carboxylase
Descriptor: pyruvate carboxylase n-terminal domain
Authors:Kondo, S, Nakajima, Y, Sugio, S, Yong-Biao, J, Sueda, S, Kondo, H.
Deposit date:2003-09-18
Release date:2004-03-09
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the biotin carboxylase subunit of pyruvate carboxylase from Aquifex aeolicus at 2.2 A resolution.
Acta Crystallogr.,Sect.D, 60, 2004
1DV1
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BU of 1dv1 by Molmil
STRUCTURE OF BIOTIN CARBOXYLASE (APO)
Descriptor: BIOTIN CARBOXYLASE, PHOSPHATE ION
Authors:Thoden, J.B, Blanchard, C.Z, Holden, H.M, Waldrop, G.L.
Deposit date:2000-01-19
Release date:2000-06-09
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Movement of the biotin carboxylase B-domain as a result of ATP binding.
J.Biol.Chem., 275, 2000
8F41
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BU of 8f41 by Molmil
3-methylcrotonyl-CoA carboxylase in filament, alpha-subunit centered
Descriptor: 3-methylcrotonyl-CoA carboxylase, alpha-subunit, beta-subunit, ...
Authors:Hu, J.J, Lee, J.K.J, Liu, Y.T, Yu, C, Huang, L, Afasizheva, I, Afasizhev, R, Zhou, Z.H.
Deposit date:2022-11-10
Release date:2023-01-11
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Discovery, structure, and function of filamentous 3-methylcrotonyl-CoA carboxylase.
Structure, 31, 2023
8F3D
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BU of 8f3d by Molmil
3-methylcrotonyl-CoA carboxylase in filament, beta-subunit centered
Descriptor: 3-methylcrotonyl-CoA carboxylase alpha-subunit, 3-methylcrotonyl-CoA carboxylase beta-subunit, 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL
Authors:Hu, J.J, Lee, J.K.J, Liu, Y.T, Yu, C, Huang, L, Afasizheva, I, Afasizhev, R, Zhou, Z.H.
Deposit date:2022-11-09
Release date:2023-01-11
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Discovery, structure, and function of filamentous 3-methylcrotonyl-CoA carboxylase.
Structure, 31, 2023
5KKN
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BU of 5kkn by Molmil
Crystal structure of human ACC2 BC domain in complex with ND-646, the primary amide of ND-630
Descriptor: 2-[1-[(2~{R})-2-(2-methoxyphenyl)-2-(oxan-4-yloxy)ethyl]-5-methyl-6-(1,3-oxazol-2-yl)-2,4-bis(oxidanylidene)thieno[2,3-d]pyrimidin-3-yl]-2-methyl-propanamide, Acetyl-CoA carboxylase 2
Authors:Wang, R, Paul, D, Tong, L.
Deposit date:2016-06-22
Release date:2016-07-13
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats.
Proc.Natl.Acad.Sci.USA, 113, 2016
4RCN
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BU of 4rcn by Molmil
Structure and function of a single-chain, multi-domain long-chain acyl-coa carboxylase
Descriptor: long-chain acyl-CoA carboxylase
Authors:Tran, T.H, Tong, L.
Deposit date:2014-09-16
Release date:2014-11-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Structure and function of a single-chain, multi-domain long-chain acyl-CoA carboxylase.
Nature, 518, 2015
5KS8
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BU of 5ks8 by Molmil
Crystal structure of two-subunit pyruvate carboxylase from Methylobacillus flagellatus
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, MANGANESE (II) ION, PYRUVIC ACID, ...
Authors:Choi, P.H, Tong, L.
Deposit date:2016-07-07
Release date:2016-10-19
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:A distinct holoenzyme organization for two-subunit pyruvate carboxylase.
Nat Commun, 7, 2016
1DV2
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BU of 1dv2 by Molmil
The structure of biotin carboxylase, mutant E288K, complexed with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, BIOTIN CARBOXYLASE
Authors:Thoden, J.B, Blanchard, C.Z, Holden, H.M, Waldrop, G.L.
Deposit date:2000-01-19
Release date:2000-06-09
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Movement of the biotin carboxylase B-domain as a result of ATP binding.
J.Biol.Chem., 275, 2000
5CSK
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BU of 5csk by Molmil
Crystal structure of yeast acetyl-CoA carboxylase, unbiotinylated
Descriptor: Acetyl-CoA carboxylase
Authors:Wei, J, Tong, L.
Deposit date:2015-07-23
Release date:2015-10-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of the 500-kDa yeast acetyl-CoA carboxylase holoenzyme dimer.
Nature, 526, 2015
2C00
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BU of 2c00 by Molmil
Crystal Structure of Biotin Carboxylase from Pseudomonas aeruginosa in apo form
Descriptor: BIOTIN CARBOXYLASE, SULFATE ION
Authors:Mochalkin, I.
Deposit date:2008-03-21
Release date:2008-09-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase.
Protein Sci., 17, 2008
1W96
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BU of 1w96 by Molmil
Crystal Structure of Biotin Carboxylase Domain of Acetyl-coenzyme A Carboxylase from Saccharomyces cerevisiae in Complex with Soraphen A
Descriptor: ACETYL-COENZYME A CARBOXYLASE, SORAPHEN A
Authors:Shen, Y, Volrath, S.L, Weatherly, S.C, Elich, T.D, Tong, L.
Deposit date:2004-10-06
Release date:2005-01-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A Mechanism for the Potent Inhibition of Eukaryotic Acetyl-Coenzyme a Carboxylase by Soraphen A, a Macrocyclic Polyketide Natural Product
Mol.Cell, 16, 2004
1W93
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BU of 1w93 by Molmil
Crystal Structure of Biotin Carboxylase Domain of Acetyl-Coenzyme A Carboxylase from Saccharomyces cerevisiae
Descriptor: ACETYL-COENZYME A CARBOXYLASE
Authors:Shen, Y, Volrath, S.L, Weatherly, S.C, Elich, T.D, Tong, L.
Deposit date:2004-10-05
Release date:2005-01-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A Mechanism for the Potent Inhibition of Eukaryotic Acetyl-Coenzyme a Carboxylase by Soraphen A, a Macrocyclic Polyketide Natural Product
Mol.Cell, 16, 2004
5CSL
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BU of 5csl by Molmil
Crystal structure of the 500 kD yeast acetyl-CoA carboxylase holoenzyme dimer
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Acetyl-CoA carboxylase, COENZYME A
Authors:Wei, J, Tong, L.
Deposit date:2015-07-23
Release date:2015-10-28
Last modified:2022-03-23
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of the 500-kDa yeast acetyl-CoA carboxylase holoenzyme dimer.
Nature, 526, 2015
4RZQ
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BU of 4rzq by Molmil
Structural Analysis of Substrate, Reaction Intermediate and Product Binding in Haemophilus influenzae Biotin Carboxylase
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Biotin carboxylase, methyl (3aS,4S,6aR)-4-(5-methoxy-5-oxopentyl)-2-oxohexahydro-1H-thieno[3,4-d]imidazole-1-carboxylate
Authors:Broussard, T.C, Pakhomova, S, Neau, D.B, Champion, T.S, Bonnot, R, Waldrop, G.L.
Deposit date:2014-12-23
Release date:2015-06-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase.
Biochemistry, 54, 2015
2DZD
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BU of 2dzd by Molmil
Crystal structure of the biotin carboxylase domain of pyruvate carboxylase
Descriptor: pyruvate carboxylase
Authors:Kondo, S, Nakajima, Y, Sugio, S, Sueda, S, Islam, M.N, Kondo, H.
Deposit date:2006-09-27
Release date:2007-09-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the biotin carboxylase domain of pyruvate carboxylase from Bacillus thermodenitrificans
ACTA CRYSTALLOGR.,SECT.D, 63, 2007
3BG5
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BU of 3bg5 by Molmil
Crystal Structure of Staphylococcus Aureus Pyruvate Carboxylase
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Xiang, S, Tong, L.
Deposit date:2007-11-26
Release date:2008-02-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of human and Staphylococcus aureus pyruvate carboxylase and molecular insights into the carboxyltransfer reaction.
Nat.Struct.Mol.Biol., 15, 2008
2YL2
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BU of 2yl2 by Molmil
Crystal structure of human acetyl-CoA carboxylase 1, biotin carboxylase (BC) domain
Descriptor: ACETYL-COA CARBOXYLASE 1
Authors:Muniz, J.R.C, Froese, D.S, Krysztofinska, E, Vollmar, M, Beltrami, A, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Yue, W.W, Oppermann, U.
Deposit date:2011-05-31
Release date:2011-06-15
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of Human Acetyl-Coa Carboxylase 1, Biotin Carboxylase (Bc) Domain
To be Published
3RUP
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BU of 3rup by Molmil
Crystal structure of E.coli biotin carboxylase in complex with two ADP and two Ca ions
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Biotin carboxylase, CALCIUM ION, ...
Authors:Chou, C.Y, Tong, L.
Deposit date:2011-05-05
Release date:2011-05-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural and biochemical studies on the regulation of biotin carboxylase by substrate inhibition and dimerization.
J.Biol.Chem., 286, 2011
3RV4
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BU of 3rv4 by Molmil
Crystal structure of E.coli biotin carboxylase R16E mutant in complex with Mg-ADP and bicarbonate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BICARBONATE ION, Biotin carboxylase, ...
Authors:Chou, C.Y, Tong, L.
Deposit date:2011-05-05
Release date:2011-05-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural and biochemical studies on the regulation of biotin carboxylase by substrate inhibition and dimerization.
J.Biol.Chem., 286, 2011
6G2H
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BU of 6g2h by Molmil
Filament of acetyl-CoA carboxylase and BRCT domains of BRCA1 (ACC-BRCT) core at 4.6 A resolution
Descriptor: Acetyl-CoA carboxylase 1
Authors:Hunkeler, M, Hagmann, A, Stuttfeld, E, Chami, M, Stahlberg, H, Maier, T.
Deposit date:2018-03-23
Release date:2018-06-13
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural basis for regulation of human acetyl-CoA carboxylase.
Nature, 558, 2018
3RV3
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BU of 3rv3 by Molmil
Crystal structure of E.coli biotin carboxylase in complex with two ADP and one Mg ion
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Biotin carboxylase, MAGNESIUM ION
Authors:Chou, C.Y, Tong, L.
Deposit date:2011-05-05
Release date:2011-05-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structural and biochemical studies on the regulation of biotin carboxylase by substrate inhibition and dimerization.
J.Biol.Chem., 286, 2011

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數據於2024-09-18公開中

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