PDB: 17 resultsInfo pagesStatus searchChemie searchBIRD

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1MWP	N-TERMINAL DOMAIN OF THE AMYLOID PRECURSOR PROTEIN Descriptor: AMYLOID A4 PROTEIN Authors: Rossjohn, J, Cappai, R, Feil, S.C, Henry, A, McKinstry, W.J, Galatis, D, Hesse, L, Multhaup, G, Beyreuther, K, Masters, C.L, Parker, M.W. Deposit date: 1999-03-09 Release date: 2000-03-15 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein. Nat.Struct.Biol., 6, 1999
4PQD	The longer crystal structure of the grow factor like domain from Beta amypoid precusor protein (APP22-126) Descriptor: Amyloid beta A4 protein Authors: Tan, X, Li, W, Wang, Z. Deposit date: 2014-03-02 Release date: 2015-04-08 Method: X-RAY DIFFRACTION (1.332 Å) Cite: Mapping the interaction betwwen APP and DR6 To be Published
3KTM	Structure of the Heparin-induced E1-Dimer of the Amyloid Precursor Protein (APP) Descriptor: (3R)-butane-1,3-diol, ACETATE ION, Amyloid beta A4 protein, ... Authors: Dahms, S.O, Hoefgen, S, Roeser, D, Schlott, B, Guhrs, K.H, Than, M.E. Deposit date: 2009-11-25 Release date: 2010-02-23 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structure and biochemical analysis of the heparin-induced E1 dimer of the amyloid precursor protein. Proc.Natl.Acad.Sci.USA, 107, 2010
4JFN	Crystal structure of the N-terminal, growth factor-like domain of the amyloid precursor protein bound to copper Descriptor: Amyloid beta A4 protein, COPPER (II) ION, GLYCEROL Authors: Wild, K, Baumkotter, F, Kins, S. Deposit date: 2013-02-28 Release date: 2014-07-23 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Amyloid precursor protein dimerization and synaptogenic function depend on copper binding to the growth factor-like domain J.Neurosci., 34, 2014
4PWQ	HIGH-RESOLUTION CRYSTAL STRUCTURE OF THE E1-DOMAIN of THE AMYLOID PRECURSOR PROTEIN Descriptor: Amyloid beta A4 protein Authors: Hoefgen, S, Dahms, S.O, Than, M.E. Deposit date: 2014-03-21 Release date: 2015-02-04 Method: X-RAY DIFFRACTION (1.4 Å) Cite: The Amyloid Precursor Protein Shows a pH-Dependent Conformational Switch in Its E1 Domain. J.Mol.Biol., 427, 2015
7MRM	Chicken CNTN3 APP complex Descriptor: Fusion protein of Chicken CNTN3 FN1-FN2 domains and Amyloid-beta A4 protein,Amyloid-beta A4 protein, SULFATE ION Authors: Bouyain, S, Karuppan, S.J. Deposit date: 2021-05-07 Release date: 2022-01-05 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Members of the vertebrate contactin and amyloid precursor protein families interact through a conserved interface. J.Biol.Chem., 298, 2021
7MRK	Chicken CNTN4 APP complex Descriptor: Amyloid-beta A4 protein, Contactin-4, DI(HYDROXYETHYL)ETHER Authors: Bouyain, S, Karuppan, S.J. Deposit date: 2021-05-07 Release date: 2022-01-05 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Members of the vertebrate contactin and amyloid precursor protein families interact through a conserved interface. J.Biol.Chem., 298, 2021
7MQY	Zebrafish CNTN4 APLP2 complex Descriptor: Fusion protein of CNTN4 and APLP2 Authors: Bouyain, S, Karuppan, S.J. Deposit date: 2021-05-07 Release date: 2022-01-05 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.46 Å) Cite: Members of the vertebrate contactin and amyloid precursor protein families interact through a conserved interface. J.Biol.Chem., 298, 2021
7MRS	Zebrafish CNTN4 APPb complex Descriptor: Amyloid-beta A4 protein, Contactin-4 Authors: Bouyain, S, Karuppan, S.J. Deposit date: 2021-05-09 Release date: 2022-01-05 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.93 Å) Cite: Members of the vertebrate contactin and amyloid precursor protein families interact through a conserved interface. J.Biol.Chem., 298, 2021
7MRN	Mouse CNTN5 APP complex Descriptor: Contactin-5, N-APP Authors: Bouyain, S, Karuppan, S.J. Deposit date: 2021-05-07 Release date: 2022-01-05 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Members of the vertebrate contactin and amyloid precursor protein families interact through a conserved interface. J.Biol.Chem., 298, 2021
8OTF	Ab typeII filament from Guam ALS/PDC Descriptor: Amyloid-beta precursor protein Authors: Qi, C, Yang, S, Scheres, S.H.W, Goedert, M. Deposit date: 2023-04-20 Release date: 2024-03-27 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold. Proc.Natl.Acad.Sci.USA, 120, 2023
8KF6	The cryo-EM structure of AV-45 bound type3 amyloid beta 42 fibril. Descriptor: P3(40) Authors: Zhao, Q.Y, Tao, Y.Q, Liu, C, Li, D. Deposit date: 2023-08-15 Release date: 2024-08-21 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: The cryo-EM structure of type1 amyloid beta 42 fibril. To Be Published
8KF5	The cryo-EM structure of type1 amyloid beta 42 fibril in AD3. Descriptor: Amyloid-beta precursor protein Authors: Zhao, Q.Y, Tao, Y.Q, Liu, C, Li, D. Deposit date: 2023-08-15 Release date: 2024-08-21 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: The cryo-EM structure of type1 amyloid beta 42 fibril in AD3. To Be Published
8KF3	The cryo-EM structure of type3 amyloid beta 42 fibril. Descriptor: Amyloid-beta precursor protein Authors: Zhao, Q.Y, Tao, Y.Q, Liu, C, Li, D. Deposit date: 2023-08-15 Release date: 2024-08-21 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: The cryo-EM structure of type1 amyloid beta 42 fibril. To Be Published
8KF4	The cryo-EM structure of type1 amyloid beta 42 fibril in AD2 patient. Descriptor: Amyloid-beta precursor protein Authors: Zhao, Q.Y, Tao, Y.Q, Liu, C, Li, D. Deposit date: 2023-08-15 Release date: 2024-08-21 Method: ELECTRON MICROSCOPY (3 Å) Cite: The cryo-EM structure of type1 amyloid beta 42 fibril in AD2 patient. To Be Published
8KEW	The cryo-EM structure of type1 amyloid beta 42 fibril. Descriptor: P3(40) Authors: Zhao, Q.Y, Tao, Y.Q, Liu, C, Li, D. Deposit date: 2023-08-13 Release date: 2024-08-14 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: The cryo-EM structure of type1 amyloid beta 42 fibril. To Be Published
8KF1	The cryo-EM structure of AV-45 bound type1 amyloid beta 42 fibril. Descriptor: 4-[2-[6-[2-[2-(2-fluoranylethoxy)ethoxy]ethoxy]pyridin-3-yl]ethyl]-~{N}-methyl-aniline, P3(40) Authors: Zhao, Q.Y, Tao, Y.Q, Liu, C, Li, D. Deposit date: 2023-08-15 Release date: 2024-08-21 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: The cryo-EM structure of AV-45 bound type1 amyloid beta 42 fibril. To Be Published