PDB: 27 件ウェブページステータス検索Chemie searchBIRD

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5U9W	Structure of CNTnw N149L in the intermediate 3 state 分子名称: 2-{[(4-O-alpha-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]methyl}-2-octyldecyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, Nucleoside permease 著者 Hirschi, M, Johnson, Z.L, Lee, S.-Y. 登録日 2016-12-18 公開日 2017-04-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.555 Å) 主引用文献 Visualizing multistep elevator-like transitions of a nucleoside transporter. Nature, 545, 2017
3TIJ	Crystal structure of a concentrative nucleoside transporter from Vibrio cholerae 分子名称: DECYL-BETA-D-MALTOPYRANOSIDE, NupC family protein, SODIUM ION, ... 著者 Johnson, Z.L, Cheong, C.-G, Lee, S.-Y. 登録日 2011-08-20 公開日 2012-03-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.436 Å) 主引用文献 Crystal structure of a concentrative nucleoside transporter from Vibrio cholerae at 2.4A Nature, 483, 2012
6KSW	Cryo-EM structure of the human concentrative nucleoside transporter CNT3 分子名称: Solute carrier family 28 member 3 著者 Zhou, Y.X, Liao, L.H, Li, J.L, Xiao, Q.J, Sun, L.F, Deng, D. 登録日 2019-08-26 公開日 2020-08-26 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Cryo-EM structure of the human concentrative nucleoside transporter CNT3. Plos Biol., 18, 2020
5L27	Structure of CNTnw N149L in the intermediate 1 state 分子名称: 2-{[(4-O-alpha-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]methyl}-2-octyldecyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, Nucleoside permease 著者 Hirschi, M, Johnson, Z.L, Lee, S.-Y. 登録日 2016-07-31 公開日 2017-04-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (4.1 Å) 主引用文献 Visualizing multistep elevator-like transitions of a nucleoside transporter. Nature, 545, 2017
5L2B	Structure of CNTnw N149S, E332A in an outward-facing state 分子名称: 2-{[(4-O-alpha-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]methyl}-2-octyldecyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, Nucleoside permease 著者 Hirschi, M, Johnson, Z.L, Lee, S.-Y. 登録日 2016-07-31 公開日 2017-04-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Visualizing multistep elevator-like transitions of a nucleoside transporter. Nature, 545, 2017
5L2A	Structure of CNTnw N149S,F366A in an outward-facing state 分子名称: 2-{[(4-O-alpha-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]methyl}-2-octyldecyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, Nucleoside permease 著者 Hirschi, M, Johnson, Z.L, Lee, S.-Y. 登録日 2016-07-31 公開日 2017-04-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Visualizing multistep elevator-like transitions of a nucleoside transporter. Nature, 545, 2017
5L26	Structure of CNTnw in an inward-facing substrate-bound state 分子名称: 2-{[(4-O-alpha-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]methyl}-2-octyldecyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, Nucleoside permease, SODIUM ION, ... 著者 Hirschi, M, Johnson, Z.L, Lee, S.-Y. 登録日 2016-07-31 公開日 2017-04-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Visualizing multistep elevator-like transitions of a nucleoside transporter. Nature, 545, 2017
5L24	Structure of CNTnw N149L in the intermediate 2 state 分子名称: 2-{[(4-O-alpha-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]methyl}-2-octyldecyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, Nucleoside permease 著者 Hirschi, M, Johnson, Z.L, Lee, S.-Y. 登録日 2016-07-31 公開日 2017-04-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (4.1 Å) 主引用文献 Visualizing multistep elevator-like transitions of a nucleoside transporter. Nature, 545, 2017
4PB2	Structure of vcCNT-7C8C bound to 5-fluorouridine 分子名称: 5-FLUOROURIDINE, DECYL-BETA-D-MALTOPYRANOSIDE, NupC family protein, ... 著者 Johnson, Z.L, Lee, S.-Y. 登録日 2014-04-11 公開日 2014-08-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.302 Å) 主引用文献 Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters. Elife, 3, 2014
4PD7	Structure of vcCNT bound to zebularine 分子名称: DECYL-BETA-D-MALTOPYRANOSIDE, NupC family protein, SODIUM ION, ... 著者 Johnson, Z.L, Lee, S.-Y. 登録日 2014-04-17 公開日 2014-08-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.909 Å) 主引用文献 Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters. Elife, 3, 2014
4PD6	Crystal structure of vcCNT-7C8C bound to uridine 分子名称: DECYL-BETA-D-MALTOPYRANOSIDE, NupC family protein, SODIUM ION, ... 著者 Johnson, Z.L, Lee, S.-Y. 登録日 2014-04-17 公開日 2014-08-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters. Elife, 3, 2014
4PD8	Structure of vcCNT-7C8C bound to pyrrolo-cytidine 分子名称: 6-methyl-3-(beta-D-ribofuranosyl)-3,7-dihydro-2H-pyrrolo[2,3-d]pyrimidin-2-one, DECYL-BETA-D-MALTOPYRANOSIDE, NupC family protein, ... 著者 Johnson, Z.L, Lee, S.-Y. 登録日 2014-04-17 公開日 2014-08-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters. Elife, 3, 2014
4PD5	Crystal structure of vcCNT-7C8C bound to gemcitabine 分子名称: DECYL-BETA-D-MALTOPYRANOSIDE, GEMCITABINE, NupC family protein, ... 著者 Johnson, Z.L, Lee, S.-Y. 登録日 2014-04-17 公開日 2014-08-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.906 Å) 主引用文献 Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters. Elife, 3, 2014
4PDA	Structure of vcCNT-7C8C bound to cytidine 分子名称: 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE, DECYL-BETA-D-MALTOPYRANOSIDE, NupC family protein, ... 著者 Johnson, Z.L, Lee, S.-Y. 登録日 2014-04-17 公開日 2014-08-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.608 Å) 主引用文献 Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters. Elife, 3, 2014
4PB1	Structure of vcCNT-7C8C bound to ribavirin 分子名称: 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide, DECYL-BETA-D-MALTOPYRANOSIDE, NupC family protein, ... 著者 Johnson, Z.L, Lee, S.-Y. 登録日 2014-04-11 公開日 2014-08-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.803 Å) 主引用文献 Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters. Elife, 3, 2014
4PD9	Structure of vcCNT-7C8C bound to adenosine 分子名称: ADENOSINE, DECYL-BETA-D-MALTOPYRANOSIDE, NupC family protein, ... 著者 Johnson, Z.L, Lee, S.-Y. 登録日 2014-04-17 公開日 2014-08-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.096 Å) 主引用文献 Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters. Elife, 3, 2014
8TZ9	Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 2, INT2-INT2-INT2 conformation 分子名称: N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter 著者 Wright, N.J, Lee, S.-Y. 登録日 2023-08-26 公開日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.67 Å) 主引用文献 Antiviral drug recognition and elevator-type transport motions of CNT3. Nat.Chem.Biol., 2024
8TZ2	Cryo-EM structure of bovine concentrative nucleoside transporter 3 in MSP2N2 nanodiscs, apo state 分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, SODIUM ION, Sodium/nucleoside cotransporter 著者 Wright, N.J, Lee, S.-Y. 登録日 2023-08-26 公開日 2024-03-13 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Antiviral drug recognition and elevator-type transport motions of CNT3. Nat.Chem.Biol., 2024
8TZD	Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 1, INT1-INT1-OFS conformation (3DVA analysis) 分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter 著者 Wright, N.J, Lee, S.-Y. 登録日 2023-08-26 公開日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Antiviral drug recognition and elevator-type transport motions of CNT3. Nat.Chem.Biol., 2024
8TZ6	Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with PSI-6206 分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2'-deoxy-2'-fluoro-2'-methyluridine, SODIUM ION, ... 著者 Wright, N.J, Lee, S.-Y. 登録日 2023-08-26 公開日 2024-03-13 実験手法 ELECTRON MICROSCOPY (2.69 Å) 主引用文献 Antiviral drug recognition and elevator-type transport motions of CNT3. Nat.Chem.Biol., 2024
8TZ3	Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with GS-441524, consensus reconstruction 分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, SODIUM ION, Sodium/nucleoside cotransporter 著者 Wright, N.J, Lee, S.-Y. 登録日 2023-08-26 公開日 2024-03-13 実験手法 ELECTRON MICROSCOPY (2.31 Å) 主引用文献 Antiviral drug recognition and elevator-type transport motions of CNT3. Nat.Chem.Biol., 2024
8TZ7	Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 1, INT1-INT1-INT1 conformation 分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter 著者 Wright, N.J, Lee, S.-Y. 登録日 2023-08-26 公開日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Antiviral drug recognition and elevator-type transport motions of CNT3. Nat.Chem.Biol., 2024
8TZ5	Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with N-hydroxycytidine 分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, N-hydroxycytidine, SODIUM ION, ... 著者 Wright, N.J, Lee, S.-Y. 登録日 2023-08-26 公開日 2024-03-13 実験手法 ELECTRON MICROSCOPY (2.74 Å) 主引用文献 Antiviral drug recognition and elevator-type transport motions of CNT3. Nat.Chem.Biol., 2024
8TZA	Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 2, INT2-INT1-INT1 conformation 分子名称: N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter 著者 Wright, N.J, Lee, S.-Y. 登録日 2023-08-26 公開日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.43 Å) 主引用文献 Antiviral drug recognition and elevator-type transport motions of CNT3. Nat.Chem.Biol., 2024
8TZ8	Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 1, INT1-INT1-INT3 conformation 分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter 著者 Wright, N.J, Lee, S.-Y. 登録日 2023-08-26 公開日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.19 Å) 主引用文献 Antiviral drug recognition and elevator-type transport motions of CNT3. Nat.Chem.Biol., 2024

 

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