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4TMP
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BU of 4tmp by Molmil
Crystal structure of AF9 YEATS bound to H3K9ac peptide
分子名称: 1,2-ETHANEDIOL, ALA-ARG-THR-LYS-GLN-THR-ALA-ARG-ALY-SER-THR, Protein AF-9
著者Li, H, Li, Y, Wang, H, Ren, Y.
登録日2014-06-02
公開日2014-11-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献AF9 YEATS Domain Links Histone Acetylation to DOT1L-Mediated H3K79 Methylation.
Cell, 159, 2014
5D7E
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BU of 5d7e by Molmil
Crystal structure of Taf14 YEATS domain in complex with H3K9ac
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, H3K9ac, ...
著者Andrews, F.H, Shanle, E.K, Strahl, B.D, Kutateladze, T.G.
登録日2015-08-13
公開日2015-09-23
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Association of Taf14 with acetylated histone H3 directs gene transcription and the DNA damage response.
Genes Dev., 29, 2015
8DKB
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BU of 8dkb by Molmil
Crystal Structure of human YEATS4 in complex with Pfizer small molecule compound 3b
分子名称: N-ethyl-1-{(3S,4S)-1-[(1-hydroxycyclohexyl)methyl]-3-methylpiperidin-4-yl}-2-methyl-1H-benzimidazole-5-carboxamide, YEATS domain-containing protein 4
著者Dias, J.M, Byrnes, L.J, Varghese, A.H.
登録日2022-07-05
公開日2023-01-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Discovery of High-Affinity Small-Molecule Binders of the Epigenetic Reader YEATS4.
J.Med.Chem., 66, 2023
7VKH
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BU of 7vkh by Molmil
Crystal structure of AF9 YEATS domain in complex with hit 2
分子名称: GLYCEROL, Protein AF-9, ~{N}-(3-azanyl-4-chloranyl-phenyl)-2-methoxy-ethanamide
著者Liu, Y, Ruan, K.
登録日2021-09-30
公開日2022-10-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Fragment-Based Discovery of AF9 YEATS Domain Inhibitors.
Int J Mol Sci, 23, 2022
6HPZ
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BU of 6hpz by Molmil
Crystal structure of ENL (MLLT1) in complex with acetyllysine
分子名称: 1,2-ETHANEDIOL, N(6)-ACETYLLYSINE, Protein ENL
著者Heidenreich, D, Chaikuad, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
登録日2018-09-22
公開日2018-11-28
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-Based Approach toward Identification of Inhibitory Fragments for Eleven-Nineteen-Leukemia Protein (ENL).
J.Med.Chem., 61, 2018
3FK3
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BU of 3fk3 by Molmil
Structure of the Yeats Domain, Yaf9
分子名称: Protein AF-9 homolog
著者Wang, A.Y, Schulze, J.M, Skordalakes, E, Berger, J.M, Rine, J, Kobor, M.S.
登録日2008-12-15
公開日2009-10-27
最終更新日2021-03-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Asf1-like structure of the conserved Yaf9 YEATS domain and role in H2A.Z deposition and acetylation
Proc.Natl.Acad.Sci.USA, 106, 2009
5R68
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BU of 5r68 by Molmil
XChem group deposition -- Crystal Structure of human YEATS4 in complex with FM000199e
分子名称: (1-methylbenzotriazol-5-yl)methanol, 1,2-ETHANEDIOL, YEATS domain-containing protein 4
著者Raux, B, Krojer, T, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Huber, K.V.M.
登録日2020-02-29
公開日2020-12-30
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献XChem group deposition
To Be Published
5R69
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BU of 5r69 by Molmil
XChem group deposition -- Crystal Structure of human YEATS4 in complex with XS038644e
分子名称: 1,2-ETHANEDIOL, YEATS domain-containing protein 4, ~{N}-(5-oxidanylidene-7,8-dihydro-6~{H}-naphthalen-2-yl)ethanamide
著者Raux, B, Krojer, T, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Huber, K.V.M.
登録日2020-02-29
公開日2020-12-30
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献XChem group deposition
To Be Published
3QRL
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BU of 3qrl by Molmil
Crystal Structure of the Taf14 YEATS domain
分子名称: TRIETHYLENE GLYCOL, Transcription initiation factor TFIID subunit 14
著者Simpson, P.J, Warren, A.J.
登録日2011-02-18
公開日2012-02-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of the Taf14 YEATS domain
To be Published
3RLS
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BU of 3rls by Molmil
Crystal structure of yeast AF-9 homolog protein Yaf9
分子名称: Protein AF-9 homolog
著者Chen, S.D, Wu, L.J, Liu, Y.F.
登録日2011-04-20
公開日2011-05-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of yeast AF-9 homolog protein yaf9
To be Published
2L7E
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BU of 2l7e by Molmil
The structure of a domain from yeast
分子名称: Transcription initiation factor TFIID subunit 14
著者Zhang, W, Zhang, J, Tu, X.
登録日2010-12-08
公開日2011-03-23
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献solution structure of Taf14 YEATS domain
To be Published
7F5M
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BU of 7f5m by Molmil
Crystal structure of Sas5 YEATS domain in complex with H3K27bz peptide
分子名称: GLYCEROL, LYS-GLN-LEU-ALA-SER-LYS-ALA-ALA-ARG-LBZ-SER-ALA-PRO-SER-THR-GLY-GLY-VAL-LYS-TYR, Something about silencing protein 5
著者Wang, D, Yan, F, Chen, Y.
登録日2021-06-22
公開日2022-03-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Global profiling of regulatory elements in the histone benzoylation pathway.
Nat Commun, 13, 2022
7F4A
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BU of 7f4a by Molmil
Crystal structure of Taf14 YEATS domain in complex with H3K9bz peptide
分子名称: Histone H3, Transcription initiation factor TFIID subunit 14
著者Wang, D, Yan, F, Yong, C.
登録日2021-06-18
公開日2022-03-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Global profiling of regulatory elements in the histone benzoylation pathway.
Nat Commun, 13, 2022
2NDF
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BU of 2ndf by Molmil
Solution NMR structures of AF9 yeats domain in complex with histon H3 acetylation at K18
分子名称: Histone H3 peptide, Protein AF-9
著者Zeng, L, Zhou, M.
登録日2016-05-19
公開日2016-09-07
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Structural Insights into Histone Crotonyl-Lysine Recognition by the AF9 YEATS Domain.
Structure, 24, 2016
2NDG
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BU of 2ndg by Molmil
Solution NMR structures of AF9 yeats domain in complex with histone H3 crotonylation at K18
分子名称: Histone H3 peptide, Protein AF-9
著者Zeng, L, Zhou, M.
登録日2016-05-19
公開日2016-09-07
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Structural Insights into Histone Crotonyl-Lysine Recognition by the AF9 YEATS Domain.
Structure, 24, 2016
7JFY
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BU of 7jfy by Molmil
GAS41 YEATS domain in complex with 5
分子名称: 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, N-(5-{3-[(2S)-1,3-thiazolidin-2-yl]azetidine-1-carbonyl}thiophen-2-yl)-L-prolinamide, ...
著者Linhares, B.M, Listunov, D, Winkler, A, Grembecka, J, Cierpicki, T.
登録日2020-07-17
公開日2021-07-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.100557 Å)
主引用文献GAS41 YEATS domain in complex with 5
To Be Published
5VNA
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BU of 5vna by Molmil
Crystal structure of human YEATS domain
分子名称: 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, SULFATE ION, ...
著者Cho, H.J, Cierpicki, T.
登録日2017-04-29
公開日2018-09-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献GAS41 Recognizes Diacetylated Histone H3 through a Bivalent Binding Mode.
ACS Chem. Biol., 13, 2018
5VNB
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BU of 5vnb by Molmil
YEATS in complex with histone H3
分子名称: 1,2-ETHANEDIOL, H3K23acK27ac peptide, SULFATE ION, ...
著者Cho, H.J, Cierpicki, T.
登録日2017-04-29
公開日2018-09-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献GAS41 Recognizes Diacetylated Histone H3 through a Bivalent Binding Mode.
ACS Chem. Biol., 13, 2018
5WYI
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BU of 5wyi by Molmil
The Yaf9 YEATS domain Recognizing H3K122suc Peptide
分子名称: (2S)-2-azanyl-6-[(4-hydroxy-4-oxo-butanoyl)amino]hexanoic acid, ILE-MET-PRO-LYS-ASP-ILE-GLN-LEU, SUCCINIC ACID, ...
著者Wang, Y, Hao, Q.
登録日2017-01-13
公開日2018-01-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Yaf9 YEATS domain Recognizing H3K122suc Peptide
To Be Published
7VKG
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BU of 7vkg by Molmil
Crystal structure of AF9 YEATS domain in complex with Compound 10
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Protein AF-9, ...
著者Liu, Y, Ruan, K.
登録日2021-09-29
公開日2022-10-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Fragment-Based Discovery of AF9 YEATS Domain Inhibitors.
Int J Mol Sci, 23, 2022
5XNV
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BU of 5xnv by Molmil
Crystal structure of YEATS2 YEATS bound to H3K27ac peptide
分子名称: ALA-ALA-ARG-ALY-SER-ALA-PRO-ALA, AMMONIUM ION, CHLORIDE ION, ...
著者Li, H.T, Guan, H.P, Zhao, D.
登録日2017-05-24
公開日2017-11-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.696 Å)
主引用文献YEATS2 links histone acetylation to tumorigenesis of non-small cell lung cancer.
Nat Commun, 8, 2017
5XTZ
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BU of 5xtz by Molmil
Crystal structure of GAS41 YEATS bound to H3K27ac peptide
分子名称: ACETATE ION, THR-LYS-ALA-ALA-ARG-ALY-SER-ALA-PRO-ALA, YEATS domain-containing protein 4
著者Li, H.T, Zhao, D.
登録日2017-06-21
公開日2018-06-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.105 Å)
主引用文献Gas41 links histone acetylation to H2A.Z deposition and maintenance of embryonic stem cell identity.
Cell Discov, 4, 2018
5Y8V
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BU of 5y8v by Molmil
Crystal structure of GAS41
分子名称: MAGNESIUM ION, YEATS domain-containing protein 4
著者Wang, Y, Hao, Q.
登録日2017-08-21
公開日2018-04-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Identification of the YEATS domain of GAS41 as a pH-dependent reader of histone succinylation
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5HJB
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BU of 5hjb by Molmil
AF9 YEATS in complex with histone H3 Crotonylation at K9
分子名称: Protein AF-9, peptide of Histone H3.1
著者Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T.
登録日2016-01-12
公開日2016-04-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain
Mol.Cell, 62, 2016
5HJD
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BU of 5hjd by Molmil
AF9 YEATS in complex with histone H3 Crotonylation at K18
分子名称: COPPER (II) ION, Protein AF-9, SULFATE ION, ...
著者Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T.
登録日2016-01-13
公開日2016-04-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.806 Å)
主引用文献Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain.
Mol.Cell, 62, 2016

 

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